Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Aldosterone-regulated sodium reabsorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
2 Aldosterone-regulated sodium reabsorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
3 Aldosterone-regulated sodium reabsorption 💬
[1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
4 Aldosterone-regulated sodium reabsorption 💬
[1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
5 Aldosterone-regulated sodium reabsorption 💬
[1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
6 Aldosterone-regulated sodium reabsorption 💬
[1] NR3C2 💬 D10528 💬 Aldosterone [1] 222 💬
7 Aldosterone-regulated sodium reabsorption 💬
[1] NR3C2 💬 D01115 💬 Eplerenone [4] 75, 113, 210, 215 💬
8 Aldosterone-regulated sodium reabsorption 💬
[1] NR3C2 💬 D07967 💬 Fludrocortisone [3]  6 , 17, 81 💬
9 Aldosterone-regulated sodium reabsorption 💬
[1] NR3C2 💬 D00443 💬 Spironolactone [8] 46, 58, 67, 86, 113, 210, 218, 225 💬
10 Aldosterone-regulated sodium reabsorption 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
11 Aldosterone-regulated sodium reabsorption 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
12 Aldosterone-regulated sodium reabsorption 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
13 Aldosterone-regulated sodium reabsorption 💬
[1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
14 Aldosterone-regulated sodium reabsorption 💬
[3] SCNN1A, SCNN1B, SCNN1G 💬 D07447 💬 Amiloride [4] 13, 67, 225, 299 💬