Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Autophagy - animal 💬
[1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 Autophagy - animal 💬
[1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
3 Autophagy - animal 💬
[1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
4 Autophagy - animal 💬
[1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
5 Autophagy - animal 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
6 Autophagy - animal 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
7 Autophagy - animal 💬
[2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
8 Autophagy - animal 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
9 Autophagy - animal 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
10 Autophagy - animal 💬
[1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
11 Autophagy - animal 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
12 Autophagy - animal 💬
[1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
13 Autophagy - animal 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
14 Autophagy - animal 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
15 Autophagy - animal 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
16 Autophagy - animal 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
17 Autophagy - animal 💬
[2] PRKCD, PRKCQ 💬 D09671 💬 Sotrastaurin [1] 97 💬
18 Autophagy - animal 💬
[1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬