Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Cell adhesion molecules 💬
[1] CD22 💬 D04036 💬 Epratuzumab [1] 49 💬
2 Cell adhesion molecules 💬
[1] CD274 💬 D10773 💬 Atezolizumab [1] 85 💬
3 Cell adhesion molecules 💬
[1] CD274 💬 D10808 💬 Durvalumab [1] 85 💬
4 Cell adhesion molecules 💬
[1] CD4 💬 D06356 💬 Zanolimumab [1] 46 💬
5 Cell adhesion molecules 💬
[1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
6 Cell adhesion molecules 💬
[1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
7 Cell adhesion molecules 💬
[1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
8 Cell adhesion molecules 💬
[1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
9 Cell adhesion molecules 💬
[1] CD58 💬 D02800 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
10 Cell adhesion molecules 💬
[1] CD6 💬 D12426 💬 Itolizumab [1] 49 💬
11 Cell adhesion molecules 💬
[2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
12 Cell adhesion molecules 💬
[2] CD80, CD86 💬 D03222 💬 Belatacept [1] 46 💬
13 Cell adhesion molecules 💬
[1] CTLA4 💬 D04603 💬 Ipilimumab [1] 159 💬
14 Cell adhesion molecules 💬
[1] CTLA4 💬 D06657 💬 Tremelimumab [1] 96 💬
15 Cell adhesion molecules 💬
[1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
16 Cell adhesion molecules 💬
[1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
17 Cell adhesion molecules 💬
[2] ITGA4, ITGB7 💬 D10540 💬 Abrilumab [2] 96, 97 💬
18 Cell adhesion molecules 💬
[2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
19 Cell adhesion molecules 💬
[1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
20 Cell adhesion molecules 💬
[1] ITGB7 💬 D09901 💬 Etrolizumab [2] 96, 97 💬
21 Cell adhesion molecules 💬
[1] PDCD1 💬 D10316 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
22 Cell adhesion molecules 💬
[1] PDCD1 💬 D10574 💬 Pembrolizumab [2] 25, 285 💬