Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD22 [1] CD22 💬 |
D04036 D04036 💬 |
Epratuzumab | 049 [1] 49 💬 |
2 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD274 [1] CD274 💬 |
D10773 D10773 💬 |
Atezolizumab | 085 [1] 85 💬 |
3 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD274 [1] CD274 💬 |
D10808 D10808 💬 |
Durvalumab | 085 [1] 85 💬 |
4 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD4 [1] CD4 💬 |
D06356 D06356 💬 |
Zanolimumab | 046 [1] 46 💬 |
5 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
6 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
7 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
8 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
9 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD58 [1] CD58 💬 |
D02800 D02800 💬 |
Alefacept | 037 [6] 37, 60, 65, 164, 284, 285 💬 |
10 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD6 [1] CD6 💬 |
D12426 D12426 💬 |
Itolizumab | 049 [1] 49 💬 |
11 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
12 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
13 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 [1] 159 💬 |
14 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
15 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 [1] 13 💬 |
16 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
17 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
18 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
19 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
20 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
21 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
PDCD1 [1] PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
22 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
PDCD1 [1] PDCD1 💬 |
D10574 D10574 💬 |
Pembrolizumab | 025 [2] 25, 285 💬 |