Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Drug metabolism - other enzymes 💬
[1] GUSB 💬 D11004 💬 Vestronidase alfa [1] 19 💬
2 Drug metabolism - other enzymes 💬
[1] HPRT1 💬 D00161 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
3 Drug metabolism - other enzymes 💬
[1] HPRT1 💬 D04931 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
4 Drug metabolism - other enzymes 💬
[1] HPRT1 💬 D08603 💬 Tioguanine [2] 13, 37 💬
5 Drug metabolism - other enzymes 💬
[2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
6 Drug metabolism - other enzymes 💬
[2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
7 Drug metabolism - other enzymes 💬
[2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
8 Drug metabolism - other enzymes 💬
[1] MPO 💬 D11684 💬 Verdiperstat [3]  2 , 17, 127 💬
9 Drug metabolism - other enzymes 💬
[1] RRM1 💬 D01370 💬 Cladribine [3] 11, 13, 94 💬
10 Drug metabolism - other enzymes 💬
[1] RRM1 💬 D03546 💬 Clofarabine [5] 19, 20, 60, 234, 326 💬
11 Drug metabolism - other enzymes 💬
[1] RRM1 💬 D07966 💬 Fludarabine [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
12 Drug metabolism - other enzymes 💬
[1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
13 Drug metabolism - other enzymes 💬
[1] XDH 💬 D00224 💬 Allopurinol [7]  6 , 46, 57, 60, 66, 96, 97 💬
14 Drug metabolism - other enzymes 💬
[1] XDH 💬 D01206 💬 Febuxostat [3]  2 ,  6 , 13 💬