Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Fc gamma R-mediated phagocytosis 💬
[1] MAP2K1 💬 D10604 💬 Binimetinib [1] 34 💬
2 Fc gamma R-mediated phagocytosis 💬
[1] MAP2K1 💬 D10405 💬 Cobimetinib [1] 280 💬
3 Fc gamma R-mediated phagocytosis 💬
[1] MAP2K1 💬 D11675 💬 Mirdametinib [1] 34 💬
4 Fc gamma R-mediated phagocytosis 💬
[1] MAP2K1 💬 D09666 💬 Selumetinib [1] 34 💬
5 Fc gamma R-mediated phagocytosis 💬
[1] MAP2K1 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
6 Fc gamma R-mediated phagocytosis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
7 Fc gamma R-mediated phagocytosis 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
8 Fc gamma R-mediated phagocytosis 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
9 Fc gamma R-mediated phagocytosis 💬
[1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
10 Fc gamma R-mediated phagocytosis 💬
[2] PRKCD, PRKCE 💬 D09671 💬 Sotrastaurin [1] 97 💬
11 Fc gamma R-mediated phagocytosis 💬
[1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
12 Fc gamma R-mediated phagocytosis 💬
[1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬