Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Pancreatic cancer 💬
[1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Pancreatic cancer 💬
[2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
3 Pancreatic cancer 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
4 Pancreatic cancer 💬
[2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
5 Pancreatic cancer 💬
[1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
6 Pancreatic cancer 💬
[1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
7 Pancreatic cancer 💬
[1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
8 Pancreatic cancer 💬
[1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
9 Pancreatic cancer 💬
[2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
10 Pancreatic cancer 💬
[2] EGFR, ERBB2 💬 D08950 💬 Neratinib [1] 34 💬
11 Pancreatic cancer 💬
[2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
12 Pancreatic cancer 💬
[1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
13 Pancreatic cancer 💬
[1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
14 Pancreatic cancer 💬
[1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
15 Pancreatic cancer 💬
[1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
16 Pancreatic cancer 💬
[1] JAK1 💬 D10653 💬 Peficitinib [1] 46 💬
17 Pancreatic cancer 💬
[1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
18 Pancreatic cancer 💬
[1] JAK1 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
19 Pancreatic cancer 💬
[1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
20 Pancreatic cancer 💬
[1] MAP2K1 💬 D10604 💬 Binimetinib [1] 34 💬
21 Pancreatic cancer 💬
[1] MAP2K1 💬 D10405 💬 Cobimetinib [1] 280 💬
22 Pancreatic cancer 💬
[1] MAP2K1 💬 D11675 💬 Mirdametinib [1] 34 💬
23 Pancreatic cancer 💬
[1] MAP2K1 💬 D09666 💬 Selumetinib [1] 34 💬
24 Pancreatic cancer 💬
[1] MAP2K1 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
25 Pancreatic cancer 💬
[1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
26 Pancreatic cancer 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
27 Pancreatic cancer 💬
[1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
28 Pancreatic cancer 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
29 Pancreatic cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
30 Pancreatic cancer 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
31 Pancreatic cancer 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
32 Pancreatic cancer 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
33 Pancreatic cancer 💬
[3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬
34 Pancreatic cancer 💬
[1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
35 Pancreatic cancer 💬
[1] VEGFA 💬 D06409 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
36 Pancreatic cancer 💬
[1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬