Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Salivary secretion 💬
 [1] ADRA1A 💬 D07124 💬 Alfuzosin [1] 13 💬
2 Salivary secretion 💬
 [1] ADRA1A 💬 D01965 💬 Silodosin [2]  6 , 13 💬
3 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
4 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D08207 💬 Methylergometrine [1] 280 💬
5 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D08220 💬 Midodrine [3]  6 , 17, 58 💬
6 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
7 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine [1] 22 💬
8 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D08560 💬 Tamsulosin [1] 13 💬
9 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D08569 💬 Terazosin [1]  6  💬
10 Salivary secretion 💬
 [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
11 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [4] 57, 86, 113, 210 💬
12 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D02349 💬 Dipivefrin [1]  6  💬
13 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
14 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00124 💬 Ephedrine [1] 11 💬
15 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
16 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine [2] 22, 296 💬
17 Salivary secretion 💬
 [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D08449 💬 Pseudoephedrine [1] 17 💬
18 Salivary secretion 💬
 [1] ADRB1 💬 D00235 💬 Atenolol [1] 167 💬
19 Salivary secretion 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [4] 58, 67, 86, 113 💬
20 Salivary secretion 💬
 [1] ADRB1 💬 D07660 💬 Celiprolol [1] 168 💬
21 Salivary secretion 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [4] 57, 58, 86, 215 💬
22 Salivary secretion 💬
 [1] ADRB1 💬 D07916 💬 Esmolol [1] 58 💬
23 Salivary secretion 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
24 Salivary secretion 💬
 [1] ADRB1 💬 D05127 💬 Nebivolol [4] 17, 85, 113, 167 💬
25 Salivary secretion 💬
 [2] ADRB1, ADRB2 💬 D00432 💬 Nadolol [1]  6  💬
26 Salivary secretion 💬
 [2] ADRB1, ADRB2 💬 D00378 💬 Timolol [2] 157, 227 💬
27 Salivary secretion 💬
 [2] ADRB1, ADRB2 💬 D08600 💬 Timolol [2] 157, 227 💬
28 Salivary secretion 💬
 [3] ADRB1, ADRB2, ADRB3 💬 D08443 💬 Propranolol [6]  6 , 158, 167, 227, 278, 296 💬
29 Salivary secretion 💬
 [1] ADRB2 💬 D07713 💬 Clenbuterol [5]  1 ,  2 ,  6 , 13, 256 💬
30 Salivary secretion 💬
 [1] ADRB2 💬 D07990 💬 Formoterol [3] 85, 228, 299 💬
31 Salivary secretion 💬
 [1] ADRB2 💬 D08092 💬 Isoxsuprine [1] 13 💬
32 Salivary secretion 💬
 [1] ADRB2 💬 D08124 💬 Levosalbutamol [1] 49 💬
33 Salivary secretion 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
34 Salivary secretion 💬
 [1] ADRB2 💬 D05792 💬 Salmeterol [1] 299 💬
35 Salivary secretion 💬
 [1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
36 Salivary secretion 💬
 [1] ADRB2 💬 D02151 💬 Tulobuterol [1]  6  💬
37 Salivary secretion 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
38 Salivary secretion 💬
 [2] AMY2A, AMY2B 💬 D00216 💬 Acarbose [1] 298 💬
39 Salivary secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
40 Salivary secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
41 Salivary secretion 💬
 [1] CD38 💬 D10777 💬 Daratumumab [5] 13, 28, 48, 49, 63 💬
42 Salivary secretion 💬
 [1] CD38 💬 D11050 💬 Isatuximab [3] 28, 61, 283 💬
43 Salivary secretion 💬
 [1] CD38 💬 D11945 💬 Mezagitamab [2] 63, 66 💬
44 Salivary secretion 💬
 [1] CHRM3 💬 D00113 💬 Atropine [2]  2 , 299 💬
45 Salivary secretion 💬
 [1] CHRM3 💬 D11383 💬 Blarcamesine [1] 156 💬
46 Salivary secretion 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
47 Salivary secretion 💬
 [1] CHRM3 💬 D00270 💬 Chlorpromazine [1] 254 💬
48 Salivary secretion 💬
 [1] CHRM3 💬 D03654 💬 Darifenacin [2]  6 , 13 💬
49 Salivary secretion 💬
 [1] CHRM3 💬 D07226 💬 Fesoterodine [1]  6  💬
50 Salivary secretion 💬
 [1] CHRM3 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
51 Salivary secretion 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
52 Salivary secretion 💬
 [1] CHRM3 💬 D08441 💬 Propiverine [1] 226 💬
53 Salivary secretion 💬
 [1] CHRM3 💬 D00138 💬 Scopolamine [1]  2  💬
54 Salivary secretion 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
55 Salivary secretion 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
56 Salivary secretion 💬
 [1] CHRM3 💬 D08638 💬 Trihexyphenidyl [2]  5 ,  6  💬
57 Salivary secretion 💬
 [1] CHRM3 💬 D00397 💬 Tropicamide [1]  6  💬
58 Salivary secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite [1] 58 💬
59 Salivary secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
60 Salivary secretion 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
61 Salivary secretion 💬
 [1] SLC12A2 💬 D00247 💬 Bumetanide [2]  6 , 158 💬
62 Salivary secretion 💬
 [1] SLC12A2 💬 D00331 💬 Furosemide [2]  6 , 86 💬