Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Pyrimidine metabolism 💬
[1] DHODH 💬 D00749 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
2 Pyrimidine metabolism 💬
[1] DHODH 💬 D10172 💬 Teriflunomide [3] 13, 25, 26 💬
3 Pyrimidine metabolism 💬
[1] RRM1 💬 D01370 💬 Cladribine [3] 11, 13, 94 💬
4 Pyrimidine metabolism 💬
[1] RRM1 💬 D03546 💬 Clofarabine [5] 19, 20, 60, 234, 326 💬
5 Pyrimidine metabolism 💬
[1] RRM1 💬 D07966 💬 Fludarabine [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
6 Pyrimidine metabolism 💬
[1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
7 Pyrimidine metabolism 💬
[1] TYMS 💬 D01244 💬 Tegafur [1] 46 💬