Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Oocyte meiosis 💬
[1] AR 💬 D03338 💬 Calusterone [1]  2  💬
2 Oocyte meiosis 💬
[1] AR 💬 D00586 💬 Flutamide [1] 81 💬
3 Oocyte meiosis 💬
[1] AR 💬 D08250 💬 Nandrolone [2] 60, 85 💬
4 Oocyte meiosis 💬
[1] AR 💬 D00955 💬 Nandrolone decanoate [2] 60, 85 💬
5 Oocyte meiosis 💬
[1] AR 💬 D00462 💬 Oxandrolone [2] 211, 285 💬
6 Oocyte meiosis 💬
[1] AR 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
7 Oocyte meiosis 💬
[1] AR 💬 D00444 💬 Stanozolol [1] 60 💬
8 Oocyte meiosis 💬
[1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
9 Oocyte meiosis 💬
[1] AR 💬 D08573 💬 Testosterone decanoate [1] 113 💬
10 Oocyte meiosis 💬
[1] AR 💬 D00958 💬 Testosterone enanthate [1] 113 💬
11 Oocyte meiosis 💬
[1] AR 💬 D08574 💬 Testosterone phenylpropionate [1] 113 💬
12 Oocyte meiosis 💬
[1] AR 💬 D00959 💬 Testosterone propionate [1] 113 💬
13 Oocyte meiosis 💬
[1] AR 💬 D06087 💬 Testosterone undecanoate [2] 13, 60 💬
14 Oocyte meiosis 💬
[2] AR, PGR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
15 Oocyte meiosis 💬
[1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
16 Oocyte meiosis 💬
[1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
17 Oocyte meiosis 💬
[1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
18 Oocyte meiosis 💬
[1] MAP2K1 💬 D10604 💬 Binimetinib [1] 34 💬
19 Oocyte meiosis 💬
[1] MAP2K1 💬 D10405 💬 Cobimetinib [1] 280 💬
20 Oocyte meiosis 💬
[1] MAP2K1 💬 D11675 💬 Mirdametinib [1] 34 💬
21 Oocyte meiosis 💬
[1] MAP2K1 💬 D09666 💬 Selumetinib [1] 34 💬
22 Oocyte meiosis 💬
[1] MAP2K1 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
23 Oocyte meiosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
24 Oocyte meiosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
25 Oocyte meiosis 💬
[1] PGR 💬 D02367 💬 Desogestrel [1] 230 💬
26 Oocyte meiosis 💬
[1] PGR 💬 D01217 💬 Dydrogesterone [1] 13 💬
27 Oocyte meiosis 💬
[1] PGR 💬 D00950 💬 Levonorgestrel [1] 13 💬
28 Oocyte meiosis 💬
[1] PGR 💬 D00951 💬 Medroxyprogesterone acetate [8] 13, 35, 46, 49, 50, 51, 60, 107 💬
29 Oocyte meiosis 💬
[1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
30 Oocyte meiosis 💬
[1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
31 Oocyte meiosis 💬
[1] PGR 💬 D07222 💬 Nomegestrol [1] 13 💬
32 Oocyte meiosis 💬
[1] PGR 💬 D08281 💬 Nomegestrol acetate [1] 13 💬
33 Oocyte meiosis 💬
[1] PGR 💬 D00182 💬 Norethisterone [4] 13, 46, 49, 299 💬
34 Oocyte meiosis 💬
[1] PGR 💬 D05209 💬 Norgestimate [1] 299 💬
35 Oocyte meiosis 💬
[1] PGR 💬 D00066 💬 Progesterone [2] 76, 299 💬
36 Oocyte meiosis 💬
[1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
37 Oocyte meiosis 💬
[1] PLK1 💬 D10154 💬 Rigosertib [1] 36 💬
38 Oocyte meiosis 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
39 Oocyte meiosis 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
40 Oocyte meiosis 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
41 Oocyte meiosis 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
42 Oocyte meiosis 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬