Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
2 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
3 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
4 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
5 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
6 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
7 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
8 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
9 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
10 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
11 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
12 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
13 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
14 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG [1] PPARG 💬 |
D12242 D12242 💬 |
Bocidelpar | 113 [1] 113 💬 |
15 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 [1] 20 💬 |
16 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
17 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
18 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 [2] 93, 94 💬 |
19 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
20 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |