Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
2 Apelin signaling pathway 💬
 [1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
3 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00522 💬 Candesartan [2] 58, 67 💬
4 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00626 💬 Candesartan cilexetil [1] 67 💬
5 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00523 💬 Irbesartan [4] 66, 167, 168, 222 💬
6 Apelin signaling pathway 💬
 [1] AGTR1 💬 D08146 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
7 Apelin signaling pathway 💬
 [1] AGTR1 💬 D11776 💬 Sparsentan [3] 66, 218, 222 💬
8 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00627 💬 Telmisartan [2] 66, 67 💬
9 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
10 Apelin signaling pathway 💬
 [1] CCN2 💬 D10969 💬 Pamrevlumab [2] 85, 113 💬
11 Apelin signaling pathway 💬
 [2] HDAC4, HDAC5 💬 D06320 💬 Vorinostat [2] 75, 96 💬
12 Apelin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
13 Apelin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
14 Apelin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
15 Apelin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
16 Apelin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
17 Apelin signaling pathway 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
18 Apelin signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
19 Apelin signaling pathway 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
20 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00227 💬 Aminophylline [1] 63 💬
21 Apelin signaling pathway 💬
 [1] PDE3B 💬 D07546 💬 Bucladesine [1] 246 💬
22 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00528 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
23 Apelin signaling pathway 💬
 [1] PDE3B 💬 D01453 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
24 Apelin signaling pathway 💬
 [1] PDE3B 💬 D01896 💬 Cilostazol [3] 46, 51, 70 💬
25 Apelin signaling pathway 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
26 Apelin signaling pathway 💬
 [1] PDE3B 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
27 Apelin signaling pathway 💬
 [1] PDE3B 💬 D04720 💬 Levosimendan [1]  2  💬
28 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
29 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00371 💬 Theophylline [2] 236, 299 💬
30 Apelin signaling pathway 💬
 [1] PDE3B 💬 D06103 💬 Theophylline [2] 236, 299 💬
31 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
32 Apelin signaling pathway 💬
 [1] PRKCE 💬 D09671 💬 Sotrastaurin [1] 97 💬
33 Apelin signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬