Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Insulin signaling pathway 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Insulin signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
3 Insulin signaling pathway 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
4 Insulin signaling pathway 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
5 Insulin signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
6 Insulin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
7 Insulin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
8 Insulin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
9 Insulin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
10 Insulin signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
11 Insulin signaling pathway 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
12 Insulin signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
13 Insulin signaling pathway 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
14 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00227 💬 Aminophylline [1] 63 💬
15 Insulin signaling pathway 💬
 [1] PDE3B 💬 D07546 💬 Bucladesine [1] 246 💬
16 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00528 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
17 Insulin signaling pathway 💬
 [1] PDE3B 💬 D01453 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
18 Insulin signaling pathway 💬
 [1] PDE3B 💬 D01896 💬 Cilostazol [3] 46, 51, 70 💬
19 Insulin signaling pathway 💬
 [1] PDE3B 💬 D07961 💬 Flavoxate [1] 226 💬
20 Insulin signaling pathway 💬
 [1] PDE3B 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
21 Insulin signaling pathway 💬
 [1] PDE3B 💬 D04720 💬 Levosimendan [1]  2  💬
22 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
23 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00371 💬 Theophylline [2] 236, 299 💬
24 Insulin signaling pathway 💬
 [1] PDE3B 💬 D06103 💬 Theophylline [2] 236, 299 💬
25 Insulin signaling pathway 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
26 Insulin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
27 Insulin signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
28 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬