Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Proximal tubule bicarbonate reclamation 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
2 Proximal tubule bicarbonate reclamation 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
3 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
4 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 D00518 💬 Diclofenamide [1] 114 💬
5 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 D07871 💬 Dorzolamide [1] 90 💬
6 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬