Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D08903 💬 Dexlansoprazole [1] 98 💬
2 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
3 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D00355 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
4 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
5 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D05353 💬 Pantoprazole [2] 13, 65 💬
6 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D08463 💬 Rabeprazole [2]  2 , 51 💬
7 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D11784 💬 Vonoprazan [2] 63, 98 💬
8 Collecting duct acid secretion 💬
[1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
9 Collecting duct acid secretion 💬
[1] CA2 💬 D00518 💬 Diclofenamide [1] 114 💬
10 Collecting duct acid secretion 💬
[1] CA2 💬 D07871 💬 Dorzolamide [1] 90 💬
11 Collecting duct acid secretion 💬
[1] CA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬