Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Huntington disease 💬
 [1] CACNA1B 💬 D01173 💬 Cilnidipine [1] 67 💬
2 Huntington disease 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
3 Huntington disease 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D08964 💬 Perampanel [3]  2 ,  6 , 144 💬
4 Huntington disease 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D02696 💬 Talampanel [2]  2 ,  6  💬
5 Huntington disease 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
6 Huntington disease 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
7 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D07058 💬 Acamprosate [2]  6 , 206 💬
8 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
9 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
10 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D07283 💬 Esketamine [3]  2 ,  4 , 70 💬
11 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
12 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D09917 💬 Latrepirdine [1]  8  💬
13 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
14 Huntington disease 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [2] 75, 96 💬
15 Huntington disease 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
16 Huntington disease 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
17 Huntington disease 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
18 Huntington disease 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
19 Huntington disease 💬
 [1] PPARG 💬 D12242 💬 Bocidelpar [1] 113 💬
20 Huntington disease 💬
 [1] PPARG 💬 D11603 💬 Leriglitazone [1] 20 💬
21 Huntington disease 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
22 Huntington disease 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
23 Huntington disease 💬
 [1] PPARG 💬 D11256 💬 Seladelpar [2] 93, 94 💬
24 Huntington disease 💬
 [1] PSMB5 💬 D03150 💬 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
25 Huntington disease 💬
 [1] PSMB5 💬 D08880 💬 Carfilzomib [1] 28 💬
26 Huntington disease 💬
 [1] PSMB5 💬 D10130 💬 Ixazomib [5] 13, 16, 28, 51, 61 💬
27 Huntington disease 💬
 [1] SOD1 💬 D11811 💬 Tofersen [1]  2  💬
28 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D11595 💬 Belantamab mafodotin [1] 28 💬
29 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D09587 💬 Brentuximab vedotin [2] 49, 51 💬
30 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
31 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00491 💬 Paclitaxel [2] 46, 85 💬
32 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08675 💬 Vinblastine [2] 34, 65 💬
33 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08679 💬 Vincristine [4] 26, 34, 65, 331 💬