Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Measles 💬
[1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 Measles 💬
[1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
3 Measles 💬
[3] CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab [1] 46 💬
4 Measles 💬
[3] CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab [2] 96, 97 💬
5 Measles 💬
[1] CD3E 💬 D11463 💬 Mosunetuzumab [1] 49 💬
6 Measles 💬
[2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
7 Measles 💬
[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
8 Measles 💬
[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
9 Measles 💬
[2] IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab [3] 46, 49, 53 💬
10 Measles 💬
[2] IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
11 Measles 💬
[2] IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
12 Measles 💬
[2] IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
13 Measles 💬
[2] IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
14 Measles 💬
[2] IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b [1] 13 💬
15 Measles 💬
[2] IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
16 Measles 💬
[2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
17 Measles 💬
[1] IL1A 💬 D11253 💬 Bermekimab [1] 51 💬
18 Measles 💬
[2] IL1A, IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
19 Measles 💬
[3] IL1A, IL1B, IL6 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
20 Measles 💬
[1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
21 Measles 💬
[1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
22 Measles 💬
[1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
23 Measles 💬
[1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
24 Measles 💬
[3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
25 Measles 💬
[1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
26 Measles 💬
[1] IL6 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
27 Measles 💬
[1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
28 Measles 💬
[1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
29 Measles 💬
[1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
30 Measles 💬
[1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
31 Measles 💬
[1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
32 Measles 💬
[1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
33 Measles 💬
[1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
34 Measles 💬
[1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
35 Measles 💬
[2] JAK1, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
36 Measles 💬
[3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
37 Measles 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
38 Measles 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
39 Measles 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
40 Measles 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
41 Measles 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
42 Measles 💬
[1] TLR7 💬 D02500 💬 Imiquimod [2] 34, 51 💬
43 Measles 💬
[1] TLR9 💬 D12275 💬 Cobitolimod [1] 97 💬
44 Measles 💬
[1] TYK2 💬 D11817 💬 Deucravacitinib [3] 49, 96, 97 💬