Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Glioma 💬	[1] BRAF 💬	D10064 💬	Dabrafenib	[1] 34 💬
2	Glioma 💬	[3] BRAF, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
3	Glioma 💬	[2] CDK4, CDK6 💬	D10688 💬	Abemaciclib	[1] 34 💬
4	Glioma 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[2] 51, 86 💬
5	Glioma 💬	[1] EGFR 💬	D07907 💬	Erlotinib	[1] 94 💬
6	Glioma 💬	[1] EGFR 💬	D01977 💬	Gefitinib	[1] 75 💬
7	Glioma 💬	[1] EGFR 💬	D11251 💬	Icotinib	[1] 34 💬
8	Glioma 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
9	Glioma 💬	[1] EGFR 💬	D08950 💬	Neratinib	[1] 34 💬
10	Glioma 💬	[1] EGFR 💬	D11772 💬	Tesevatinib	[1] 67 💬
11	Glioma 💬	[1] IGF1R 💬	D09925 💬	Linsitinib	[1] 232 💬
12	Glioma 💬	[1] IGF1R 💬	D03297 💬	Mecasermin	[6] 65, 78, 96, 168, 265, 299 💬
13	Glioma 💬	[1] IGF1R 💬	D09680 💬	Teprotumumab	[1] 51 💬
14	Glioma 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
15	Glioma 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
16	Glioma 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
17	Glioma 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
18	Glioma 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
19	Glioma 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
20	Glioma 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
21	Glioma 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[1] 13 💬
22	Glioma 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
23	Glioma 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
24	Glioma 💬	[2] PDGFRA, PDGFRB 💬	D10481 💬	Nintedanib	[5] 51, 85, 89, 227, 228 💬
25	Glioma 💬	[2] PDGFRA, PDGFRB 💬	D08552 💬	Sunitinib	[2] 28, 34 💬
26	Glioma 💬	[1] PDGFRB 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
27	Glioma 💬	[1] PDGFRB 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
28	Glioma 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
29	Glioma 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
30	Glioma 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
31	Glioma 💬	[1] PRKCB 💬	D11935 💬	Enzastaurin	[1] 168 💬