Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Non-small cell lung cancer 💬
 [1] ALK 💬 D10866 💬 Brigatinib [1] 34 💬
2 Non-small cell lung cancer 💬
 [1] ALK 💬 D09731 💬 Crizotinib [1] 34 💬
3 Non-small cell lung cancer 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
4 Non-small cell lung cancer 💬
 [3] BRAF, RAF1, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
5 Non-small cell lung cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
6 Non-small cell lung cancer 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
7 Non-small cell lung cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
8 Non-small cell lung cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
9 Non-small cell lung cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
10 Non-small cell lung cancer 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
11 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
12 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 D08950 💬 Neratinib [1] 34 💬
13 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
14 Non-small cell lung cancer 💬
 [1] JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
15 Non-small cell lung cancer 💬
 [1] JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
16 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
17 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
18 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
19 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
20 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
21 Non-small cell lung cancer 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
22 Non-small cell lung cancer 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
23 Non-small cell lung cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
24 Non-small cell lung cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
25 Non-small cell lung cancer 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
26 Non-small cell lung cancer 💬
 [1] RARB 💬 D04162 💬 Fenretinide [1] 299 💬
27 Non-small cell lung cancer 💬
 [1] RARB 💬 D00348 💬 Isotretinoin [4] 36, 39, 159, 160 💬
28 Non-small cell lung cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
29 Non-small cell lung cancer 💬
 [1] RARB 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
30 Non-small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin [1] 37 💬
31 Non-small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin [1] 49 💬
32 Non-small cell lung cancer 💬
 [1] RET 💬 D08552 💬 Sunitinib [2] 28, 34 💬
33 Non-small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬