Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 [2] 46, 61 💬 |
2 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 [3] 46, 49, 53 💬 |
3 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D12467 D12467 💬 |
Evobrutinib | 013 [3] 13, 46, 49 💬 |
4 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 [1] 13 💬 |
5 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 [3] 28, 60, 61 💬 |
6 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 [4] 13, 49, 61, 63 💬 |
7 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D12285 D12285 💬 |
Remibrutinib | 013 [2] 13, 53 💬 |
8 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 013 [5] 13, 63, 222, 300, 331 💬 |
9 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
10 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD19 [1] CD19 💬 |
D11496 D11496 💬 |
Obexelimab | 300 [1] 300 💬 |
11 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3D [2] CD3D, CD3E 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
12 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3D [2] CD3D, CD3E 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
13 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
14 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD4 [1] CD4 💬 |
D06356 D06356 💬 |
Zanolimumab | 046 [1] 46 💬 |
15 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
16 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
17 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
18 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
19 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
IL2RG [1] IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
20 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
JAK3 [1] JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
21 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
JAK3 [1] JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
22 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
LCK [1] LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
23 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
LCK [1] LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
24 | Primary immunodeficiency 💬 Related to 11 target genes, 23 drugs (DrugBank) and 26 diseases in DDrare |
TNFRSF13C [1] TNFRSF13C 💬 |
D12151 D12151 💬 |
Ianalumab | 035 [7] 35, 46, 49, 53, 61, 63, 95 💬 |