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e.g. Sirolimus, Adalimumab

ABCDEFGH I JKLMNOPQRSTUVWXYZother

101 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  2,2-bis(4-hydroxy-3-tert-butylphenyl)propane - -  -  -  [4] 19, 86, 276, 299 💬
 2  Abatacept [36] Abatacept; Abatacept (aba); Abatacept (aba) + methotrexate (mtx), double-blind (db); Abatacept (bms-188667); Abatacept (ctla4-ig); Abatacept (iv); Abatacept (sc); Abatacept + csdmard; Abatacept + methotrexate; Abatacept + vaccines; Abatacept active treatment; Abatacept delayed-onset treatment; Abatacept injection; Abatacept placebo; Abatacept prefilled syringe; Abatacept sc; Abatacept subcutaneous; Abatacept, rituximab or tocilizumab; Adalimuab, etanercept, tocilizumab, or abatacept; Bdmard withdrawal (etanercept, adalimumab, infliximab, certolizumab, golimumab, tozilizumab, abatacept); Bms 188667 (abatacept); Decrease tocilizumab, abatacept; Device: abatacept combination product (acp); Double-blind abatacept; Drug: abatacept; Etanercepet, rituximab, abatacept, tocilizumab, sarilumab; Intravenous (iv) abatacept; Iv abatacept; Open-label abatacept; Orencia (abatacept); Orencia abatacept; Orencia® (abatacept); Subcutaneous (sc) abatacept; Subcutaneous abatacept; Subcutaneous(sc) abatacept; Tocilizumab, abatacept;  [1] D03203 💬 [2] CD80, CD86 💬 [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis  [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
 3  Acetylcysteine [12] Acetylcysteine; Acetylcysteine effervescent tablets; Acetylcysteine sodium; Fluimucil (acetylcysteine); Glatiramer acetate, n-acetylcysteine; Jaktinib dihydrochloride monohydrate 50mg bid and mimic tablets of jakitinib hydrochloride 75mg bid and acetylcysteine effervescent tablets; Jaktinib dihydrochloride monohydrate 75mg bid and mimic tablets of jakitinib hydrochloride 50mg bid and acetylcysteine effervescent tablets; N acetylcysteine; N-acetylcysteine; N-acetylcysteine (nac); N-acetylcysteine capsule; N-acetylcysteine, (nac);  [1] D00221 💬  -  -  [17]  6 , 13, 19, 20, 34, 49, 51, 58, 85, 90, 94, 111, 164, 193, 233, 298, 299 💬
 4  Adalimumab [76] Adalimumab; Adalimumab (40 mg); Adalimumab (ada); Adalimumab (d2e7); Adalimumab (humira); Adalimumab (humira®); Adalimumab (up to 9 months exposure); Adalimumab - gp2017; Adalimumab - us licensed humira; Adalimumab 40 mg; Adalimumab 40 mg eow or ew; Adalimumab 40 mg sc every other week; Adalimumab 40 mg subcutaneous (sc) every other week (eow); Adalimumab 40mg q2w; Adalimumab 80 mg; Adalimumab and infliximab; Adalimumab humira; Adalimumab injection; Adalimumab injection [humira]; Adalimumab pfs and pen; Adalimumab prn; Adalimumab with methotrexate; Adalimumab, current formulation; Adalimumab, etanercept, golimumab or infliximab; Adalimumab, new formulation; Adalimumab, plus prednisone; Adalimumab, solution for injection 40 mg/ (0.8 ml) pre-filled syringe; Adalimumab-eu; Adalimumab-pfizer; Amgevita (adalimumab biosimilar ); Anti-tnf therapy (etanercept or adalimumab); Anti-tnf:adalimumab (subcutaneus); Application of adalimumab; Azathioprine or adalimumab and infliximab; Bdmard withdrawal (etanercept, adalimumab, infliximab, certolizumab, golimumab, tozilizumab, abatacept); Biosimilar product to adalimumab; Ct-p17 sc ai (adalimumab); Db adalimumab 40 mg eow; Db adalimumab 40 mg ew; Device: adalimumab delivered in current autoinjector; Device: adalimumab delivered in current syringe; Device: adalimumab delivered in physiolis autoinjector; Device: adalimumab delivered in physiolis syringe; Diagnostic test: adalimumab serum trough concentration; Diagnostic test: adalimumab trough concentration; Double-blind adalimumab; Etanercept or adalimumab; Fitc-adalimumab; Gp2017 (adalimumab biosimilar); Humira (adalimumab original); Humira (adalimumab); Humira (adalimumab) 40 mg in 0.4 ml s.c. injection; Humira (adalimumab) 40 mg s.c. injection; Humira (adalimumab) 40mg in 0.4 ml s.c. injection; Humira (adalimumab) 40mg in 0.4ml s.c.injection; Humira 40mg solution for injection in pre-filled syringe (adalimumab); Humira ® (adalimumab) 40mg/0.8ml pre-filled syringe; Humira® (adalimumab); Infliximab and adalimumab; Infliximab or adalimumab or golimumab or vedolizumab or ustekinumab; Infliximab, adalimumab, certolizumab pegol; Infliximab, etanercept, adalimumab; Methotrexate,adalimumab; New formulation adalimumab; Ol adalimumab 40 mg; Open-label adalimumab; Open-labeladalimumabrescue; Other: adalimumab; Other: adalimumab treatment; Other: lengthening adalimumab dosing interval; Other: measurement of drug (adalimumab/infliximab); Sb5 (proposed biosimilar to adalimumab); Start adalimumab in monotherapy; Tnf blockers (infliximab, adalimumab, etanercept); Treatment with adalimumab; Tumor necrosis factor inhibitor (etanercept, infliximab, adalimumab, and golimumab);  [1] D02597 💬 [1] TNF 💬 [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
 5  Adrabetadex [1] Adrabetadex;  -  -  -  [1] 19 💬
 6  Afegostat [2] Afegostat; Afegostat tartrate;  [1] D09576 💬  -  -  [1] 19 💬
 7  Agalsidase alfa [3] Agalsidase alfa; Replagal (agalsidase alfa); Replagal agalsidase alfa;  [1] D02784 💬 [1] GLA 💬 [6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism  [1] 19 💬
 8  Agalsidase beta [4] Agalsidase beta; Agalsidase beta (gz419828); Agalsidase beta (recombinant form); Fabrazyme (agalsidase beta);  [1] D03228 💬 [1] GLA 💬 [6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism  [1] 19 💬
 9  Alemtuzumab [20] Alemtuzumab; Alemtuzumab (already received by alemtuzumab cohort between 1991 and 1994; Alemtuzumab (already received by alemtuzumab cohort between 1991 and 1994); Alemtuzumab (campath ); Alemtuzumab (campath); Alemtuzumab (gz402673); Alemtuzumab 0.2 mg; Alemtuzumab 0.3 mg; Alemtuzumab 12 mg; Alemtuzumab 24 mg; Alemtuzumab and rituximab; Alemtuzumab gz402673; Alemtuzumab immunotherapy; Alemtuzumab injection; Alemtuzumab injection [lemtrada]; Alemtuzumab, rituximab; Campath-1h (alemtuzumab); Filgrastim, alemtuzumab; Transplant conditioning with mobilization and alemtuzumab; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [1] D02802 💬  -  -  [21] 13, 15, 19, 20, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
 10  Alendronic acid [1] Alendronic acid;  [2] D00939
D07119 💬		 [1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis  [7] 19, 41, 46, 50, 271, 274, 299 💬
 11  Alglucerase - [1] D02810 💬 [1] GBA 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism  [1] 19 💬
 12  Ambroxol [2] Ambroxol; Ambroxol hydrochloride;  [1] D07442 💬  -  -  [2]  6 , 19 💬
 13  Amoxicillin [8] Amoxicillin; Amoxicillin and clavulanic acid; Amoxicillin and tetracycline; Amoxicillin hydrate; Amoxicillin, metronidazole and tetracycline; Clartihromycin, amoxicillin, and omeprazole; Lansoprazole, amoxicillin, clarithromycin; Takecab tablets + amoxicillin + clarithromycin (first-line eradication) takecab tablets + amoxicillin + metronidazole (second-line eradication);  [3] D00229
D02925
D07452 💬		  -  -  [9]  6 , 19, 46, 63, 84, 96, 97, 222, 299 💬
 14  Anakinra [8] Anakinra; Anakinra (kineret®); Anakinra (r-methuil-1ra); Anakinra / kineret; Anakinra and peg stnf-r1; Kineret® (anakinra); Kineret® or anakinra; Response to anakinra associated with methotrexate;  [1] D02934 💬 [2] IL1R1, IL1R2 💬 [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer  [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 15  Angiotensin II [2] Angiotensin ii; Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin);  [2] D00150
D02014 💬		 [2] AGTR1, AGTR2 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [7] 17, 19, 46, 66, 86, 222, 224 💬
 16  Arimoclomol [4] Arimoclomol; Arimoclomol (hard gelatine capsule); Arimoclomol (hpmc capsule); Arimoclomol citrate;  [1] D11374 💬  -  -  [3]  2 , 15, 19 💬
 17  Ataluren [9] Ataluren; Ataluren (ptc124®); Ataluren 1000 mg; Ataluren 1000mg; Ataluren 125 mg; Ataluren 125mg; Ataluren 250 mg; Ataluren 250mg; Ivacaftor/ataluren;  [1] D09323 💬  -  -  [6] 19, 113, 140, 246, 299, 329 💬
 18  Azathioprine [38] Azathioprine; Azathioprine (aza); Azathioprine (aza) caps; Azathioprine (aza) or 6-mercaptopurine (6-mp); Azathioprine (imuran) 50 mg overencapsulated tablet; Azathioprine - ratiopharm 50 mg; Azathioprine / 6 mercaptopurine; Azathioprine 25 mg; Azathioprine and allopurinol; Azathioprine in case of endoscopic recurrence; Azathioprine individualised dose; Azathioprine or 6-mercaptopurine; Azathioprine or adalimumab and infliximab; Azathioprine or mesalazine; Azathioprine or methotrexate; Azathioprine or mycophenolate mofetil; Azathioprine weight-based dose; Azathioprine+enteral nutrition; Azathioprine/prednisone; Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine; Continuation of azathioprine; Corticosteroid and azathioprine; Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids; Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Cyclophosphamide-prednisone-azathioprine; Early immunosuppressants (azathioprine, methotrexate); Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate); Infliximab and azathioprine combination at week 0; Infliximab and azathioprine combination at week 14; Infliximab with azathioprine (iifx + aza); Infliximab+azathioprine; Infliximab, azathioprine; Overencapsulated azathioprine (imuran) 50 mg tablet; Prednisone - azathioprine; Products containing azathioprine or 6-mercaptopurine; Rituximab (rtx) and azathioprine (aza); Steroids plus azathioprine; Symptomatic treatment, steroids, immunosuppressive agents( azathioprine, tacrolimus, mycophenolate mofetil);  [2] D00238
D03033 💬		  -  -  [20]  6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬
 19  Barium [4] Barium; Diagnostic test: barium esophagram; Procedure: speech and modified barium swallow study; Radiation: esophageal barium xray;  -  -  -  [2] 19, 98 💬
 20  Betadex [1] Adrabetadex;  [1] D02401 💬  -  -  [1] 19 💬
 21  Busulfan [15] Busulfan; Busulfan iv; Busulfan test dose; Busulfan, cyclophosphamide, antithymocyte globulin; Busulfan, cyclophosphamide, atg; Busulfan, cyclophosphamide, atg, gcsf; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Busulfan, fludarabine and atg; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Busulfan, fludarabine, atg, tli; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Busulfano; Campath, busulfan, clofarabine; Fludarabine, busulfan, thymoglobulin; Fludarabine/busulfan;  [1] D00248 💬  -  -  [13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
 22  Calcium [34] Amorphous calcium carbonate; Ascal(r) / carbasalate calcium; Atorvastatin calcium; Calcitriol & calcium; Calcium; Calcium and cholecalciferol; Calcium and vitamin d combination; Calcium carbonate; Calcium carbonate and alphacalcidol; Calcium carbonate d; Calcium channel blockers; Calcium citrate; Calcium citrate with vitamin d2; Calcium gluconate; Calcium lactate; Calcium levofolinate; Calcium rosuvastatin; Calcium, dietary; Carbasalate calcium; Crestor tablets (calcium rosuvastatin) film-coated tablets; Crystalline calcium supplements; Ethylhydrogenfumarat, calciumsalz; Ibandronate+alfacalcidol+calcium; Low molecular weight heparin calcium injection; Other: calcium stable isotope; Other: determination of calcium intake by a dietician interview; Other: empiric use of calcium carbonate and calcitriol; Other: pth based calcium carbonate and calcitriol repletion; Other: serum calcium concentrations results; Rosuvastatin calcium; Rosuvastatin calcium 40mg; Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin); Vidofludimus calcium; Vidofludimus calcium dihydrate;  -  -  -  [27]  6 , 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
 23  Calcium carbonate [6] Amorphous calcium carbonate; Calcium carbonate; Calcium carbonate and alphacalcidol; Calcium carbonate d; Other: empiric use of calcium carbonate and calcitriol; Other: pth based calcium carbonate and calcitriol repletion;  [2] D00932
D10802 💬		  -  -  [8] 13, 19, 46, 53, 75, 96, 235, 299 💬
 24  Capsaicin [5] Capsaicin; Capsaicin challenge; Capsaicin vapor; Other: challenge agent: capsaicin; Qutenza (8% capsaicin);  [1] D00250 💬 [1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction  [5]  2 ,  6 , 19, 86, 226 💬
 25  Carbonate ion - -  -  -  [12]  2 , 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
 26  Cerliponase alfa [1] Cerliponase alfa;  [1] D10813 💬 [1] TPP1 💬 [1] Lysosome  [1] 19 💬
 27  Cholecalciferol [11] 5000 iu of cholecalciferol; Calcium and cholecalciferol; Cholecalciferol; Cholecalciferol (vitamin d3); Cholecalciferol (vitamind3); Cholecalciferol 10,000 iu; Cholecalciferol 400 iu; Cholecalciferol and c. xanthorrhiza; Cholecalciferol concentrate; Cholecalciferol concentrate (water-dispersible form); Cholecalciferol, vitamin d3;  [1] D00188 💬 [1] VDR 💬 [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
 28  Cholesterol [10] 3h-cholesterol bound to albumin; Cholesterol; Cholesterol supplementation; Crystalline cholesterol oil-based suspension; Egg substitute, without cholesterol; Egg yolk preparation with cholesterol; Lysosomal acid lipase, esterase cholesterol (human gene lipa), lysosomal acid lipase (human gene lipa); Lysosomal acid lipase, esterase, cholesterol (human gene lipa), lysosomal acid lipase (human gene lipa); Recombinant human lysosomal acid lipase (rhlal), esterase, cholesterol (human gene lipa); Recombinant human lysosomal acid lipase (rhlal), esterase, cholesterol (human gene lipa), lysosomal acid lipase (human gene lipa);  [1] D00040 💬  -  -  [6] 19, 90, 160, 259, 261, 310 💬
 29  Clofarabine [3] Campath, busulfan, clofarabine; Clofarabine; Radiation: fluorine f 18 clofarabine;  [1] D03546 💬 [3] POLA1, POLA2, RRM1 💬 [6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
 30  Cyclophosphamide [55] Busulfan, cyclophosphamide, antithymocyte globulin; Busulfan, cyclophosphamide, atg; Busulfan, cyclophosphamide, atg, gcsf; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Campath, fludarabine, cyclophosphamide; Cyclophosphamide; Cyclophosphamide (cy); Cyclophosphamide (cy) (plan 1); Cyclophosphamide (cy) (plan 2); Cyclophosphamide (cytoxan); Cyclophosphamide (drug); Cyclophosphamide + pred; Cyclophosphamide 100mg; Cyclophosphamide 150mg; Cyclophosphamide 30; Cyclophosphamide 40; Cyclophosphamide 50mg; Cyclophosphamide 50mg oral tablet; Cyclophosphamide and atg; Cyclophosphamide and fludarabine; Cyclophosphamide and steroids; Cyclophosphamide dose level 1; Cyclophosphamide dose level 2; Cyclophosphamide dose level 3; Cyclophosphamide dose level 4; Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids; Cyclophosphamide injection 1g; Cyclophosphamide monohydrate; Cyclophosphamide post transplant; Cyclophosphamide(ctx); Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Cyclophosphamide, bortezomib, and dexamethasone (cybord); Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Cyclophosphamide, fludarabine; Cyclophosphamide, fludarabine , thymoglobulin; Cyclophosphamide, fludarabine, rabbit atg; Cyclophosphamide, fludarabine, thymoglobulin; Cyclophosphamide,campath ih and tbi; Cyclophosphamide,cyclosporine a; Cyclophosphamide-prednisone-azathioprine; Cyclophosphamide/glatiramer acetate; Fludarabine, cyclophosphamide; Haploidentical hsct using tbi free regimen, ''atg'' with ''post transplant cyclophosphamide''; High-dose cyclophosphamide; Iv cyclophosphamide; Lenalidomide, dexamethasone and cyclophosphamide; Prednisone and cyclophosphamide; Prednisone plus cyclophosphamide; Prednisone, cyclophosphamide; Prednisone, methylprednisolone,cyclophosphamides; Procedure: cyclophosphamide; Rituximab and cyclophosphamide iv; Thalidomide, cyclophosphamide and prednisone;  [2] D00287
D07760 💬		  -  -  [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
 31  Cyclosporine [26] Atg+cyclosporine; Atg+rapamune+cyclosporine; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Cyclophosphamide,cyclosporine a; Cyclosporine; Cyclosporine (gengraf ); Cyclosporine (usan); Cyclosporine 5 mg/kg bid days 0-14; Cyclosporine a; Cyclosporine a (csa); Cyclosporine a dry powder inhalation (drug); Cyclosporine combine with mycophenolate mofetil; Cyclosporine inhalation solution; Cyclosporine inhalation solution (cis); Cyclosporine oral product; Cyclosporine pill; Cyclosporine vs infliximab; Cyclosporine-a; Device: cyclosporine a; Liposomal aerosol cyclosporine; Liposomal cyclosporine a; Liposomal cyclosporine a 10 mg; Liposomal cyclosporine a 5 mg; Oral cyclosporine; Rabbit atg, cyclosporine, levamisole; Twice-daily dosage with 0.5% cyclosporine-a eyedrops;  [1] D00184 💬 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
 32  Cysteamine [13] Cystagon (cysteamine bitartrate) immediate-release capsules; Cystagon® (cysteamine bitartrate); Cysteamine; Cysteamine (mercaptamine) viscous solution; Cysteamine bitartrate; Cysteamine bitartrate (cystagon); Cysteamine bitartrate (inn: mercaptamine bitartrate; Cysteamine bitartrate (inn: mercaptamine bitartrate ); Cysteamine bitartrate (inn: mercaptamine bitartrate); Cysteamine bitartrate delayed-release capsules; Cysteamine bitartrate delayed-release capsules (rp103); Cysteamine hydrochloride; Other: cysteamine bitartrate;  [2] D03634
D03635 💬		  -  -  [4]  8 , 19, 21, 299 💬
 33  Cysteine [17] Acetylcysteine; Acetylcysteine effervescent tablets; Cysteine; Cysteine hydrochloride; Glatiramer acetate, n-acetylcysteine; Intravenous and oral n-acetyl cysteine; Jaktinib dihydrochloride monohydrate 50mg bid and mimic tablets of jakitinib hydrochloride 75mg bid and acetylcysteine effervescent tablets; Jaktinib dihydrochloride monohydrate 75mg bid and mimic tablets of jakitinib hydrochloride 50mg bid and acetylcysteine effervescent tablets; N acetyl cysteine; N acetylcysteine; N-acetyl cysteine; N-acetyl cysteine (nac); N-acetyl-cysteine; N-acetylcysteine; N-acetylcysteine (nac); N-acetylcysteine capsule; N-acetylcysteine, (nac);  [2] D00026
D02326 💬		  -  -  [11]  6 , 13, 19, 34, 84, 85, 88, 90, 254, 296, 310 💬
 34  Eliglustat [3] Eliglustat; Eliglustat gz385660; Eliglustat tartrate;  [1] D09893 💬 [1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism  [1] 19 💬
 35  Elosulfase alfa [3] Elosulfase alfa; Elosulfase alfa 1 mg/ml intravenous solution [vimizim]; Vimizim® (elosulfase alfa);  [1] D10333 💬 [1] GALNS 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways  [1] 19 💬
 36  ELX-02 [1] Elx-02;  -  -  -  [2] 19, 299 💬
 37  Enalapril [4] Enalapril; Enalapril and other angiotensin converting enzyme inhibitors; Enalapril maleate; Enalapril valsartan methylprednisone;  [2] D00621
D07892 💬		 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system  [7] 19, 46, 66, 113, 210, 222, 223 💬
 38  Fludarabine [24] Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Busulfan, fludarabine and atg; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Busulfan, fludarabine, atg, tli; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Campath, fludarabine, cyclophosphamide; Cyclophosphamide and fludarabine; Cyclophosphamide, fludarabine; Cyclophosphamide, fludarabine , thymoglobulin; Cyclophosphamide, fludarabine, rabbit atg; Cyclophosphamide, fludarabine, thymoglobulin; Fludarabine; Fludarabine (flu); Fludarabine monophosphate; Fludarabine phosphate; Fludarabine phosphate 30 mg; Fludarabine phosphate 40 mg; Fludarabine, busulfan, thymoglobulin; Fludarabine, cyclophosphamide; Fludarabine, melphalan, thiotepa; Fludarabine/ melphalan; Fludarabine/busulfan; Sq fludarabine; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [2] D01907
D07966 💬		 [1] RRM1 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
 39  Fluorescein [2] Fluorescein; Other: fluorescein angiography;  [2] D01261
D02024 💬		  -  -  [2] 19, 97 💬
 40  Gabapentin [9] Gabapentin; Gabapentin prescriptions; Gabapentina; Gabapentina kern pharma; Gabapentine; Gabapentine 300mg; Multi-modal pain management [acetaminophen + gabapentin]; Multi-modal pain management [valium + gabapentin]; Transdermal fentanyl matrix, gabapentin;  [1] D00332 💬 [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬 [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [5]  6 , 13, 19, 70, 298 💬
 41  Galsulfase [2] Galsulfase; Naglazyme (galsulfase);  [1] D06565 💬 [1] ARSB 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways  [1] 19 💬
 42  Gamolenic acid - [1] D07213 💬  -  -  [3] 13, 19, 46 💬
 43  Gelatin [8] Arimoclomol (hard gelatine capsule); Bio-enhanced curcumin soft gelatin capsule; Gelatin; Gelatine; Neoral soft gelatin capsules; Tafamidis meglumine 20 mg soft gelatin capsules; Tafamidis meglumine 20mg soft gelatin capsule (clinical trial image); Tafamidis meglumine 20mg soft gelatin capsule (commerical image);  [2] D00115
D06892 💬		  -  -  [6] 19, 28, 78, 97, 269, 299 💬
 44  Genistein [5] Genistein; Genistein (unconjugated isoflavones 100); Genistein aglycone; Genisteine plus 150 mg cpl formaat 1 18,7 x 6,4 mm 438 mg; Unconjugated isoflavones 100 (pti g-4660, 87% genistein);  [1] D11680 💬  -  -  [2] 19, 299 💬
 45  Hydroxypropyl betadex - -  -  -  [1] 19 💬
 46  Hydroxyurea [1] Hydroxyurea;  [1] D00341 💬 [1] RRM2 💬 [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway  [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 47  Idursulfase [11] Idursulfase; Idursulfase (i2s); Idursulfase (i2s)-it; Idursulfase beta; Idursulfase it (1 mg); Idursulfase it (10 mg); Idursulfase it (30 mg); Idursulfase(12s)-it; Idursulfase(i2s)-it; Idursulfase-it; Jr-141 or idursulfase;  [1] D04499 💬 [1] IDS 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways  [1] 19 💬
 48  Idursulfase beta [1] Idursulfase beta;  [1] D11025 💬 [1] IDS 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways  [1] 19 💬
 49  Imidacloprid - -  -  -  [5] 19, 20, 125, 234, 326 💬
 50  Imiglucerase [4] Cerezyme (imiglucerase for injection); Cerezyme® / imiglucerase; Imiglucerase; Imiglucerase gz437843;  [2] D02810
D03020 💬		 [1] GBA 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism  [1] 19 💬
 51  Insulin-like growth factor II - -  -  -  [1] 19 💬
 52  Iohexol [2] Iohexol; Iohexol inj 300 milligrams per milliliter (mg/ml);  [1] D01817 💬  -  -  [2] 19, 67 💬
 53  L-Lysine [6] L-lysine; L-lysine n acetylcysteinate; L-lysine n-acetylcysteinate; L-lysine- n-acetylcysteinate; L-lysine-n-acetyl-l-cysteinate; L-lysine-n-acetylcysteinate;  [1] D02304 💬  -  -  [5] 13, 19, 97, 228, 299 💬
 54  Laronidase [4] Aldurazyme (laronidase); Irt laronidase; Laronidase; Laronidase ert;  [1] D04670 💬 [1] IDUA 💬 [3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways  [2] 19, 256 💬
 55  Ledipasvir [2] Ledipasvir; Ledipasvir/sofosbuvir;  [1] D10442 💬  -  -  [2] 19, 254 💬
 56  Lenograstim [3] Granocyte - 34 million iu (lenograstim rhug-csf); Granocyte lenograstim; Lenograstim;  [1] D03247 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [7]  2 , 13, 16, 18, 19, 57, 65 💬
 57  Leucine [8] Administration of stable isotope-labelled leucine-; Diagnostic test: serum leucine-rich alpha-2 glycoprotein (lrg) levels; Essential amino acid intake + leucine vs total aa supplement; L-leucine; Leucine; N acetyl l leucine; N-acetyl-l-leucine; Other: 13c6 leucine;  [1] D00030 💬  -  -  [10]  5 ,  6 ,  7 , 19, 96, 97, 127, 283, 284, 299 💬
 58  Leucovorin [2] Leucovorin; Methotrexate, leucovorin and bms-986142;  [3] D01211
D07986
D07987 💬		  -  -  [2] 19, 46 💬
 59  Levothyroxine [2] Levothyroxine; Other: levothyroxine;  [2] D01010
D08125 💬		 [2] THRA, THRB 💬 [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway  [4] 19, 49, 78, 222 💬
 60  Lisinopril [4] Coenzyme q10 and lisinopril; Lisinopril; Lisinopril pills; Lisinopril, losartan, and atorvastatin;  [2] D00362
D08131 💬		 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system  [7] 19, 46, 49, 66, 67, 113, 222 💬
 61  Lithium carbonate [1] Lithium carbonate;  [1] D00801 💬  -  -  [6]  2 , 13, 17, 18, 19, 127 💬
 62  Losartan [12] Lisinopril, losartan, and atorvastatin; Losartan; Losartan and atenolol or propranolol; Losartan and nebivolol; Losartan and other angiotensin receptor blockers; Losartan bluefish 50 mg; Losartan hexal; Losartan potasico; Losartan potassium; Losartan tablets & qingremoshen granule; Other: losartan; Sildenafil and losartan;  [2] D00357
D08146 💬		 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
 63  Lucerastat [1] Lucerastat;  [1] D11439 💬 [1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism  [1] 19 💬
 64  Melphalan [10] Carmustine, etoposide, cytarabine, and melphalan (beam); Fludarabine, melphalan, thiotepa; Fludarabine/ melphalan; Melphalan; Melphalan fulfenamide hydrochloride; Melphalan hydrochloride; Melphalan, thalidomide and dexamethasone; Melphalan-flufenamide (melflufen); Propylene glycol-free melphalan hydrochloride; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [1] D00369 💬  -  -  [15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
 65  Methamidophos - -  -  -  [18]  2 , 11, 13, 19, 46, 49, 58, 65, 70, 85, 86, 98, 113, 118, 129, 298, 299, 300 💬
 66  Methotrexate [113] Abatacept (aba) + methotrexate (mtx), double-blind (db); Abatacept + methotrexate; Adalimumab with methotrexate; Azathioprine or methotrexate; Bms-582949 and methotrexate; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Certolizumab pegol + methotrexate (mtx); Clobetasol propionate + methotrexate; Combination product: methotrexate; Cp-690,550 + methotrexate; Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids; Cyclosporin, methotrexate (gvhd prophylaxis); Dmards (methotrexate; Early immunosuppressants (azathioprine, methotrexate); Etanercept + methotrexate; Etanercept , methotrexate; Etanercept, methotrexate and depomedrone; Etanercept, methotrexate, prednisolone; Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate); Infliximab + methotrexate (mtx); Infliximab, methylprednisolone, methotrexate; Intrathecal methotrexate; Methotrexate; Methotrexate 'lederle' 2,5mg tablets; Methotrexate 'lederle' 2.5mg tablets; Methotrexate 'lederle' tablets; Methotrexate (metoject® prefilled pen); Methotrexate (mtx); Methotrexate (stable dose); Methotrexate (tapering dose); Methotrexate + biologic administration; Methotrexate + infliximab; Methotrexate + methylprednisolone; Methotrexate + salazopyrine + hydroxychloroquine administration; Methotrexate - amneal; Methotrexate - dava; Methotrexate - delay; Methotrexate - etanercept - prednisolone arm; Methotrexate - immediate; Methotrexate 10 mg; Methotrexate 10 mg tablets; Methotrexate 2.5 mg; Methotrexate 2.5 mg tablets; Methotrexate 2.5mg tablets; Methotrexate 2.5mg tablets bp; Methotrexate 25 mg; Methotrexate 50mg/ml solution for injection, pre-filled syringe; Methotrexate ``lederle`` 2.5mg tablets; Methotrexate and folic acid; Methotrexate as methotrexate disodium; Methotrexate bellon; Methotrexate bellon 25mg/ml; Methotrexate capsules; Methotrexate disodium; Methotrexate ebewe; Methotrexate hospira 2,5 mg tablety; Methotrexate hospira 2.5 mg tablety; Methotrexate injection; Methotrexate lachema 5inj. sol; Methotrexate lederle 2.5 mg tablets; Methotrexate pfizer 2,5 mg tabletter; Methotrexate placebo; Methotrexate plus enbrel or enbrel alone; Methotrexate plus erb-041 for 12 weeks; Methotrexate plus sulfasalazine; Methotrexate pre-filled pen; Methotrexate prefilled pen; Methotrexate prefilled syringe; Methotrexate sodium; Methotrexate sodium 2.5mg tablets; Methotrexate sodium tablets 2.5 mg; Methotrexate sodium tablets 2.5mg; Methotrexate tablets; Methotrexate tablets 2.5 mg; Methotrexate treatment; Methotrexate wyeth 2,5mg; Methotrexate wyeth 2,5mg tbl.; Methotrexate ® 2.5mg tablets; Methotrexate(mtx); Methotrexate(mtx) administration is at the discretion of the rheumatologist and no tradename is fixed by the protocol; Methotrexate(mtx) administration is at the discretion of the rheumatologist and no tradename is fixed by the protocol.; Methotrexate(necessary); Methotrexate*100cpr 2,5mg; Methotrexate*10mg/1,33ml 4s; Methotrexate*15mg/2ml 4sir; Methotrexate*2,5mg 25cpr; Methotrexate*20mg/2,66ml 4s; Methotrexate*25cpr 2,5mg; Methotrexate*7,5mg/ml 4sir.; Methotrexate, leucovorin and bms-986142; Methotrexate,adalimumab; Methotrexate-lachema; Methotrexate-sulfasalazine-hydroxychloroquine; Methotrexate® 2.5 mg tablets; Mp-435(dose1) + methotrexate; Mycophenolate mofetil,methotrexate; Oral methotrexate; Other: methotrexate therapy; Phase 1: methotrexate; Response to anakinra associated with methotrexate; Response to infliximab associated with methotrexate; Stable weekly dose of methotrexate; Tacrolimus with methotrexate; Tak-715 and methotrexate; Tak-783 and methotrexate; Tasocitinib plus methotrexate; Tocilizumab + methotrexate(mtx); Tocilizumab plus methotrexate; Tocilizumab+methotrexate(mtx); Tofacitinib with methotrexate; Tofacitinib without methotrexate; Treatment with systemic therapy (methotrexate); Urine samples taken to measure methotrexate and its major metabolite 7-oh-methotrexate level;  [2] D00142
D02115 💬		 [2] DHFR, DHFR2 💬 [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate  [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
 67  Methylprednisolone [35] Administration of rituximab and methylprednisolone; Corticosteroid treatment (methylprednisolone or prednisolone); Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Infliximab, methylprednisolone, methotrexate; Interferon-beta-1a (avonex) plus methylprednisolone; Intravenous (i.v.) methylprednisolone 1000 mg, total 9; Intravenous methylprednisolone; Iv methylprednisolone; Iv methylprednisolone (steroids); Megadose oral methylprednisolone; Methotrexate + methylprednisolone; Methylprednisolone; Methylprednisolone (drug); Methylprednisolone (mp); Methylprednisolone (mp) or prednisone (pred); Methylprednisolone (or other glucocorticoid); Methylprednisolone (solu-medrol); Methylprednisolone 1250 mg/24h x3 days; Methylprednisolone acetate; Methylprednisolone bolus iv 15 mg/kg/d for 3 days.; Methylprednisolone hemisuccinate; Methylprednisolone iv; Methylprednisolone mylan générique; Methylprednisolone or budesonide; Methylprednisolone or prednisolone; Methylprednisolone po; Methylprednisolone pulse; Methylprednisolone sodium hemisuccinate; Methylprednisolone sodium succinate; Methylprednisolone(intravenously in the 1st-2nd-3rd month ); Methylprednisolone(intravenously in the 1st-3rd-5th month); Oral 5-asa+/-topical 5-asa+iv corticosteroids / po methylprednisolone; Oral methylprednisolone 625 mg/24h x3 days; Prednisone (and methylprednisolone); Prednisone, methylprednisolone,cyclophosphamides;  [6] D00407
D00751
D00979
D05000
D05001
D05002 💬		 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
 68  Migalastat [12] A (migalastat); B (migalastat); C (migalastat); D (migalastat); E (migalastat); Iv migalastat hcl; Migalastat; Migalastat hcl; Migalastat hcl 150 mg; Migalastat hydrochloride; Migalastat hydrocloride; Oral migalastat hcl;  [1] D10359 💬  -  -  [1] 19 💬
 69  Miglustat [4] Miglustat; Miglustat (at2221); Miglustat (zavesca); Zavesca (miglustat);  [1] D05032 💬 [1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism  [3] 19, 256, 299 💬
 70  Mycophenolate mofetil [19] Azathioprine or mycophenolate mofetil; Cellcept (mycophenolate mofetil); Cyclosporine combine with mycophenolate mofetil; Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate); Mycophenolate mofetil; Mycophenolate mofetil (cellcept); Mycophenolate mofetil (mmf); Mycophenolate mofetil (mmf) 3 g/day; Mycophenolate mofetil 2 g/day; Mycophenolate mofetil [cellcept]; Mycophenolate mofetil orally 1000 mg twice a day (bid); Mycophenolate mofetil plus lower dose of prednisone; Mycophenolate mofetil(mmf); Mycophenolate mofetil, low dose steroid; Mycophenolate mofetil,methotrexate; Prednisolone and mycophenolate mofetil; Prednisone and mycophenolate mofetil; Prednisone, ciclosporin and mycophenolate mofetil; Symptomatic treatment, steroids, immunosuppressive agents( azathioprine, tacrolimus, mycophenolate mofetil);  [3] D00752
D05094
D05095 💬		 [2] IMPDH1, IMPDH2 💬 [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
 71  Mycophenolic acid [2] Mycophenolic acid; Mycophenolic acid mofetil;  [1] D05096 💬 [2] IMPDH1, IMPDH2 💬 [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
 72  Odiparcil [1] Odiparcil;  -  -  -  [1] 19 💬
 73  Olenasufligene relduparvovec [1] Olenasufligene relduparvovec;  -  -  -  [1] 19 💬
 74  Olipudase alfa [2] Olipudase alfa; Olipudase alfa (rhasm);  [1] D10820 💬 [1] SMPD1 💬 [5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway  [1] 19 💬
 75  Oxygen [39] Behavioral: respiratory and exercise therapy with supplemental oxygen; Combination product: hyperbaric oxygen therapy-; Continuous oxygen; Device: auto-titrating oxygen system; Device: capacity of muscular oxygen extraction; Device: high flow nasal oxygen cannula; Device: hyperbaric oxygen; Device: intermittent exposure to oxygen via oro-nasal mask; Device: nocturnal oxygen , nocturnal bi-level positive pressure ventilation; Device: oxygen; Device: oxygen saturation; Device: standard oxygen therapy/ra; Diagnostic test: maximum oxygen uptake; Helium / oxygen mixed gas inhalation therapy; Medical air vs oxygen; Medical grade oxygen; Nitric oxide plus oxygen; Other: 60% oxygen; Other: air - oxygen; Other: hyperbaric oxygen; Other: hyperbaric oxygen therapy; Other: muscle oxygenation; Other: optional blood-oxygen-level dependent functionalmri; Other: oxygen; Other: oxygen (2liter/min); Other: oxygen (4liter/min); Other: oxygen - air; Other: oxygen supplementation; Oxygen; Oxygen 40 %; Oxygen supplementation; Oxygen, liquid; Perfluorinated gas/oxygen mixture; Procedure: hyperbaric oxygen; Procedure: hyperbaric oxygen therapy; Procedure: long term oxygen therapy; Procedure: oxygen flow at the optic nerve head measurement; Procedure: supplemental oxygen via a mask; Standard analgesia use [oxygen];  [1] D00003 💬  -  -  [18]  6 , 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 294, 299, 330 💬
 76  Paricalcitol [1] Paricalcitol;  [1] D00930 💬 [1] VDR 💬 [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [3] 19, 66, 218 💬
 77  Pegunigalsidase alfa [2] Pegunigalsidase alfa; Prx-102 (pegunigalsidase alfa);  [1] D11685 💬  -  -  [1] 19 💬
 78  Pentosan polysulfate [3] Pentosan polysulfate; Pentosan polysulfate sodium; Pentosan polysulfate sodium 100 mg;  [1] D05428 💬  -  -  [3] 19, 26, 226 💬
 79  Plerixafor [3] Plerixafor; Plerixafor for conditioning before hsct.; Plerixafor mobilization of autologous cd117 stem cells;  [1] D08971 💬 [1] CXCR4 💬 [12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor  [6] 19, 20, 51, 65, 285, 299 💬
 80  Prednisone [73] 0 mg prednisone; 5 mg prednisone; 5-aminosalicylic acid(5-asa) and/or prednisone; Adalimumab, plus prednisone; Azathioprine/prednisone; Chinese herb prescription granule plus prednisone; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Corticosteroids (prednisone or prednisolone); Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Cyclophosphamide-prednisone-azathioprine; Enalapril valsartan methylprednisone; Glucocorticoid (prednisone or prednisolone); Granulocyte-colony stimulating factor (g-csf) and prednisone; Hormone (prednisone); Hydroxychloroquine + prednisone; Ir prednisone; Leflunomide 20 mg+prednisone 0.5mg/kg/d; Methylprednisolone (mp) or prednisone (pred); Methylprednisone; Mr prednisone; Mycophenolate mofetil plus lower dose of prednisone; Oral prednisone; Oral prednisone 5mg; Other: prednisone; Over encapsulated prednisone; Prednisolone/prednisone; Prednisone; Prednisone (and methylprednisolone); Prednisone + inhibace/cozaar; Prednisone - azathioprine; Prednisone 0,5 mg/kg orally on alternate days; Prednisone 1 mg; Prednisone 15 mg; Prednisone 2 mg; Prednisone 3 mg; Prednisone 4 mg; Prednisone 5 mg; Prednisone 5 mg tablets; Prednisone 7.5 mg; Prednisone acetate; Prednisone acetate tablets; Prednisone alone; Prednisone and belimumab; Prednisone and cyclophosphamide; Prednisone and mycophenolate mofetil; Prednisone and ustekinumab treatment; Prednisone arrow 20mg; Prednisone arrow 5 mg; Prednisone capsules; Prednisone discontinuation; Prednisone in full dose; Prednisone or prednisolone; Prednisone plus cyclophosphamide; Prednisone tablets usp, 1 mg; Prednisone tablets usp, 2.5 mg; Prednisone tablets usp, 5 mg; Prednisone tablets, usp; Prednisone therapy and pharmacokinetic; Prednisone treatment; Prednisone, ciclosporin and mycophenolate mofetil; Prednisone, cyclophosphamide; Prednisone, fk506, mmf; Prednisone, low dose rituximab; Prednisone, methylprednisolone,cyclophosphamides; Prednisone/prednisolone; Procedure: thymectomy plus prednisone; Rayos (delayed-release prednisone); Sotatercept with prednisone boost; Tacrolimus combined with prednisone; Thalidomide, cyclophosphamide and prednisone; Treatment systemic therapy (prednisone); Treatment with systemic therapy (prednisone); Ursodeoxycholic acid+low dose glucocorticoid(prednisone);  [1] D00473 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
 81  Pyrimethamine [2] Fansidar (pyrimethamine and sulfadoxine); Pyrimethamine;  [1] D00488 💬  -  -  [10]  2 ,  4 ,  6 , 19, 46, 51, 65, 96, 97, 265 💬
 82  Quinapril - [2] D00459
D03752 💬		 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system  [1] 19 💬
 83  Rimiducid [1] Rimiducid;  [1] D11195 💬 [1] CASP9 💬 [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway  [6] 19, 60, 65, 284, 285, 326 💬
 84  Rituximab [67] Abatacept, rituximab or tocilizumab; Abp 798 - biosimilar to rituximab; Abp 798 biosimilar to rituximab; Administration of rituximab and methylprednisolone; Alemtuzumab and rituximab; Alemtuzumab, rituximab; Bendamustine, rituximab; Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine; Combined plasma exchange (pex), rituximab, and corticosteroids; Dexamethasone and rituximab; Double-blind rituximab; Dr. reddy’s rituximab (drl_ri) 100mg; Dr. reddy’s rituximab (drl_ri) 500mg; Eltrombopag combining rituximab; Etanercepet, rituximab, abatacept, tocilizumab, sarilumab; Experimental (non immunosuppressive symptomatic treatment (nist) and rituximab); Gp2013 - a proposed biosimilar rituximab; Idec-c2b8 (rituximab); Immunosuppressive treatment (eg, rituximab); Individualized dose of rituximab; Intravenous rituximab; Mabthera (rituximab); Mabthera or biosimilar rituximab product; Mabthera® (rituximab); Originator rituximab - rituxan ® or mabthera ®; Prednisone, low dose rituximab; Rhtpo in combination with rituximab; Rituxan (inn: rituximab), brand name in the united states; Rituxan (inn: rituximab), brand name in the us; Rituxan (rituximab); Rituxan® (rituximab); Rituximab; Rituximab (anti-cd20); Rituximab (arm a); Rituximab (arm b); Rituximab (eu); Rituximab (genetical recombination); Rituximab (mabthera® or rituxan®).; Rituximab (mabthera®); Rituximab (rituxan); Rituximab (rtx) and azathioprine (aza); Rituximab (us); Rituximab - mabthera; Rituximab 1g iv; Rituximab [mabthera/rituxan]; Rituximab [mabthera]; Rituximab and cyclophosphamide iv; Rituximab combined with omalizumab; Rituximab infusion; Rituximab it; Rituximab iv; Rituximab konsentrat til infusjonsvaeske oppløsning 10 mg/ml; Rituximab mabthera; Rituximab or rituximab hyaluronidase human; Rituximab, mabthera; Rituximab, mtx, folic acid; Rituximab, observational study amon patients with active ra; Rituximab-eu+ rituximab-pfizer x 2 courses; Rituximab-pfizer; Rituximab-pfizer (pf-05280586) x 3 courses; Rituximab-us + rituximab-pfizer x 2 courses; Rituximab/ mabthera; Sait101 (proposed rituximab biosimilar); Sait101 (rituximab biosimilar); Standard dose of rituximab; The standard steroid treatment, plasma exchange and rituximab; [rituximab];  [1] D02994 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage  [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
 85  Sebelipase alfa [5] Sebelipase alfa; Sebelipase alfa (sbc-102); Sebelipase alfa 0.35 mg/kg; Sebelipase alfa 1 mg/kg; Sebelipase alfa 3 mg/kg;  [1] D10377 💬 [1] LIPA 💬 [3] Cholesterol metabolism, Lysosome, Steroid biosynthesis  [1] 19 💬
 86  Sirolimus [22] Rapamycin, sirolimus; Sirolimus; Sirolimus (formerly known as rapamycin); Sirolimus (study drug)+ace inhibitor + statin; Sirolimus 0,1% crème; Sirolimus 0.2%; Sirolimus 0.4%; Sirolimus 1mg/ml; Sirolimus 2 mg; Sirolimus 2%; Sirolimus and hydroxychloroquine 200 mg; Sirolimus and hydroxychloroquine 400 mg; Sirolimus ointment; Sirolimus oral liquid product 1mg/ml; Sirolimus oral product; Sirolimus, 2%; Skincerity plus sirolimus/rapamycin; Skinercity plus sirolimus/rapamycin; Tavt-18 (sirolimus); Temsirolimus; Temsirolimus tablets; Topical 0.1% sirolimus;  [1] D00753 💬 [1] MTOR 💬 [50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway  [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
 87  SOBI-003 [1] Sobi003;  -  -  -  [1] 19 💬
 88  Sofosbuvir [2] Ledipasvir/sofosbuvir; Sofosbuvir;  [1] D10366 💬  -  -  [2] 19, 254 💬
 89  Somatotropin [3] Recombinant human somatotropin; Somatotropin; Somatotropine;  [1] D02691 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
 90  Taliglucerase alfa [2] Taliglucerase alfa; Taliglucerase alfa - recombinant human glucocerebrosidase;  [1] D09675 💬 [1] GBA 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism  [1] 19 💬
 91  Thiotepa [5] Fludarabine, melphalan, thiotepa; Thiotepa; Thiotepa--escalated dose; Thiotepa--single daily dose; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [1] D00583 💬  -  -  [11] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284 💬
 92  Treosulfan [3] Ovastat 1000 (treosulfan injection); Ovastat 5000 (treosulfan injection); Treosulfan;  [1] D07253 💬  -  -  [3] 13, 19, 65 💬
 93  Tropicamide [5] 0 mg tropicamide; 0.3 mg tropicamide; 1 mg tropicamide; 3 mg tropicamide; Tropicamide;  [1] D00397 💬 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 [13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway  [2]  6 , 19 💬
 94  Velaglucerase alfa [4] Ga-gcb (velaglucerase alfa); Gene activated human glucocerebrosidase, velaglucerase alfa; Velaglucerase alfa; Velaglucerase alfa (vpriv);  [1] D09029 💬 [1] GBA 💬 [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism  [1] 19 💬
 95  Velmanase alfa [2] Velmanase alfa; Velmanase alfa (e.g. lamazym);  [1] D11024 💬 [1] MAN2B1 💬 [2] Lysosome, Other glycan degradation  [1] 19 💬
 96  Venglustat [5] Venglustat; Venglustat (gz/sar402671); Venglustat gz/sar402671; Venglustat gz402671; Venglustat malate;  [1] D11633 💬 [1] UGCG 💬 [2] Metabolic pathways, Sphingolipid metabolism  [3]  6 , 19, 67 💬
 97  Vestronidase alfa - [1] D11004 💬 [1] GUSB 💬 [8] Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism  [1] 19 💬
 98  Vitamin D [36] 10000iu vitamin d; 19 nor vitamin d; 25-hydroxyvitamin d3; 25oh-vitamin d; 5000iu vitamin d; Alendronate versus alfacalcidol (1-alpha oh vitamin d); Calcium and vitamin d combination; Cholecalciferol (vitamin d3); Cholecalciferol, vitamin d3; D6-25-hydroxyvitamin d3; Diagnostic test: vitamin d measurement; Ergocalciferol (vitamin d2); High-dose vitamin d (2000 iu per day); High-dose vitamin d3; Low dose arm receiving neutral oil and 400 iu/g of vitamin d every second day; Other: baseline serum vitamin d level at or above 50 nmol/l; Other: baseline serum vitamin d level below 50 nmol/l; Standard-dose vitamin d (400iu per day); Supplementation with vitamin d2/d3; Verum arm receiving vitamin d oil; Vitamin d; Vitamin d 100ug; Vitamin d 10ug; Vitamin d 25(oh)d; Vitamin d drops; Vitamin d in arm b; Vitamin d oil; Vitamin d powder; Vitamin d2; Vitamin d3; Vitamin d3 3000 ui daily; Vitamin d3 400 iu; Vitamin d3 4000 ui daily; Vitamin d3 6000 iu; Vitamin d3 800 ui/day then 800 ui/day; Vitamin d3: 3000 or 4000 ui/day then 2,000 ui/day;  -  -  -  [21] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 274, 298, 299 💬
 99  Vorinostat [1] Vorinostat;  [1] D06320 💬 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 [17] Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis  [3] 19, 75, 96 💬
 100  Warfarin [6] S-warfarin; The generic name is warfarin and many producers will be involved; Warfarin; Warfarin 10 mg; Warfarin sodium; Warfarin+ vitamin k;  [3] D00564
D01280
D08682 💬		 [2] NQO1, VKORC1 💬 [6] Biosynthesis of cofactors, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis  [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬
 101  Water [31] 15 o water; 15-o labeled water; 5% glucose water solution; Behavioral: diet and water adjustment; Behavioral: water tracking; Cholecalciferol concentrate (water-dispersible form); Device: manual toothbrush and water flosser (philips sonicare airfloss); Device: sonic toothbrush (philips sonicare) and water flosser (philips sonicare airfloss); Dextrose, 5% in water; High water intake; Lactose in water; Other: ad libitum water intake; Other: dead sea solar and water treatment; Other: dextrose water 5%; Other: exercise followed cold water immersion; Other: harkány medicinal water; Other: high water intake; Other: potable water; Other: water; Other: water prescription; Pl 12185/0002 & pl 12185/0005(water for injection); Procedure: water exercises; Pseudoephedrine + 480 ml water; Pseudoephedrine + 50 ml water; Sterile water; Sterile water for injection; Sterilised water for injections; Water; Water for injection; Water for injections; Water for injections, ep;  [1] D00001 💬  -  -  [22]  2 ,  5 ,  6 , 13, 17, 19, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299 💬