750 mg metformin and 7.5 g l-citrulline daily p.o. (DrugBank: Citrulline, L-Citrulline, Metformin)
21 diseasesID | Disease name (Link within this page) | Number of trials |
---|---|---|
2 | Amyotrophic lateral sclerosis | 0 |
6 | Parkinson disease | 0 |
13 | Multiple sclerosis/Neuromyelitis optica | 0 |
46 | Malignant rheumatoid arthritis | 0 |
49 | Systemic lupus erythematosus | 0 |
60 | Aplastic anemia | 0 |
67 | Polycystic kidney disease | 0 |
75 | Cushing disease | 0 |
77 | Growth hormone secreting pituitary adenoma | 0 |
81 | Congenital adrenal hyperplasia | 0 |
86 | Pulmonary arterial hypertension | 0 |
113 | Muscular dystrophy | 1 |
127 | Frontotemporal lobar degeneration | 0 |
158 | Tuberous sclerosis | 0 |
206 | Fragile X syndrome | 0 |
225 | Congenital nephrogenic diabetes insipidus | 0 |
233 | Wolfram syndrome | 0 |
265 | Lipodystrophy | 0 |
285 | Fanconi anemia | 0 |
299 | Cystic fibrosis | 0 |
301 | Macular dystrophy | 0 |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT01995032 (ClinicalTrials.gov) | October 2013 | 20/11/2013 | L-citrulline and Metformin in Duchenne's Muscular Dystrophy | A Double Blind Randomised Placebo Controlled Efficacy and Safety Study of L-citrulline and Metformin in Ambulant Children Aged Between 7 and 10 Years With Duchenne's Muscular Dystrophy | Duchenne's Muscular Dystrophy (DMD) | Drug: 750 mg metformin and 7.5 g L-citrulline daily p.o.;Drug: Placebo | University Hospital, Basel, Switzerland | NULL | Completed | 78 Months | 10 Years | All | 47 | Phase 3 | Switzerland |