DDrare: Database of Drug Development for Rare Diseases

Naltrexone-hcl (DrugBank: Naltrexone)

13 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	0
10	Charcot-Marie-Tooth disease	0
13	Multiple sclerosis/Neuromyelitis optica	0
40	Takayasu arteritis	0
41	Giant cell arteritis	0
42	Polyarteritis nodosa	0
43	Microscopic polyangiitis	0
44	Wegener granulomatosis	0
45	Eosinophilic granulomatosis with Polyangiitis	0
46	Malignant rheumatoid arthritis	0
96	Crohn disease	1
97	Ulcerative colitis	0
226	Interstitial cystitis with Hunners ulcer	0

6. Parkinson disease [ 2,123 clinical trials, 2,046 drugs, (DrugBank: 324 drugs), 183 drug target genes, 198 drug target pathways]

Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,123 trial found

10. Charcot-Marie-Tooth disease [ 31 clinical trials, 38 drugs, (DrugBank: 9 drugs), 11 drug target genes, 14 drug target pathways]

Searched query = "Charcot-Marie-Tooth disease", "CMT"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 31 trial found

13. Multiple sclerosis/Neuromyelitis optica [ 3,050 clinical trials, 2,147 drugs, (DrugBank: 348 drugs), 244 drug target genes, 228 drug target pathways]

Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 3,050 trial found

40. Takayasu arteritis [ 22 clinical trials, 46 drugs, (DrugBank: 20 drugs), 22 drug target genes, 111 drug target pathways]

Searched query = "Takayasu arteritis", "Aortitis syndrome", "Pulseless disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 22 trial found

41. Giant cell arteritis [ 108 clinical trials, 111 drugs, (DrugBank: 32 drugs), 33 drug target genes, 121 drug target pathways]

Searched query = "Giant cell arteritis", "Temporal arteritis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 108 trial found

42. Polyarteritis nodosa [ 14 clinical trials, 27 drugs, (DrugBank: 16 drugs), 26 drug target genes, 102 drug target pathways]

Searched query = "Polyarteritis nodosa", "PAN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 14 trial found

43. Microscopic polyangiitis [ 85 clinical trials, 80 drugs, (DrugBank: 19 drugs), 13 drug target genes, 85 drug target pathways]

Searched query = "Microscopic polyangiitis", "MPA"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 85 trial found

44. Wegener granulomatosis [ 84 clinical trials, 88 drugs, (DrugBank: 22 drugs), 13 drug target genes, 37 drug target pathways]

Searched query = "Wegener granulomatosis", "Multiple vasculitis granulomatous disease", "Granulomatosis with polyangiitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 84 trial found

45. Eosinophilic granulomatosis with Polyangiitis [ 27 clinical trials, 41 drugs, (DrugBank: 18 drugs), 18 drug target genes, 98 drug target pathways]

Searched query = "Eosinophilic granulomatosis with Polyangiitis", "EGPA", "Eosinophilic multiple vasculitis granulomatous disease", "Allergic granulomatous angiitis", "Churg-Strauss syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 27 trial found

46. Malignant rheumatoid arthritis [ 4,183 clinical trials, 2,538 drugs, (DrugBank: 401 drugs), 183 drug target genes, 219 drug target pathways]

Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 4,183 trial found

96. Crohn disease [ 2,209 clinical trials, 1,276 drugs, (DrugBank: 240 drugs), 166 drug target genes, 210 drug target pathways]

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 2,209 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00663117 (ClinicalTrials.gov)	September 2006	18/4/2008	The Effects of Naltrexone on Active Crohn's Disease	The Effects of Naltrexone in Active Crohn's Disease	Inflammation;Crohn's Disease	Drug: Naltrexone-HCl;Drug: Placebo	Milton S. Hershey Medical Center	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);The Broad Foundation	Completed	18 Years	75 Years	All	40	Phase 2	United States

97. Ulcerative colitis [ 2,269 clinical trials, 1,331 drugs, (DrugBank: 241 drugs), 114 drug target genes, 181 drug target pathways]

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,269 trial found

226. Interstitial cystitis with Hunners ulcer [ 133 clinical trials, 151 drugs, (DrugBank: 46 drugs), 48 drug target genes, 137 drug target pathways]

Searched query = "Interstitial cystitis with Hunners ulcer", "Interstitial cystitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 133 trial found