Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Bosentan
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2Bosentan (Tracleer)1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
3Bosentan 125 mg
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
4Bosentan 62.5 mg
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
5Bosentan administration
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
6Bosentan and Sildenafil
(Tracleer (TN))		2件: Bosentan (Tracleer),
Sildenafil		3件: Bosentan (Tracleer (TN)),
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
7Bosentan group
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
8BOSENTAN MONOHIDRATO
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
9Bosentan monohydrat
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
10BOSENTAN MONOHYDRATE
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 51, 84, 86, 88 💬
11BOSENTAN MYLAN
(Tracleer (TN))		1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 41 💬
12Bosentan, Ambrisentan
(Tracleer (TN))		2件: Ambrisentan,
Bosentan (Tracleer)		3件: Bosentan (Tracleer (TN)),
Ambrisentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
13Duo-Therapy with Sildenafil + Bosentan
(Tracleer (TN))		2件: Bosentan (Tracleer),
Sildenafil		3件: Bosentan (Tracleer (TN)),
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
14ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Tracleer (TN))		4件: Bosentan (Tracleer),
Macitentan,
Sildenafil,
Tadalafil		5件: Bosentan (Tracleer (TN)),
Tadalafil ,
Bosentan ,
Sildenafil ,
Macitentan 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
15Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi4件: Epoprostenol,
Iloprost,
Macitentan,
Selexipag		4件: Epoprostenol ,
Iloprost ,
Selexipag ,
Macitentan 💬 		3件: EDNRA,
EDNRB,
PTGIR 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
16Sildenafil 20mg and Bosentan 62.5mg
(Tracleer (TN))		2件: Bosentan (Tracleer),
Sildenafil		3件: Bosentan (Tracleer (TN)),
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 86 💬
17Sildenafil singly or in association with Bosentan
(Tracleer (TN))		2件: Bosentan (Tracleer),
Sildenafil		3件: Bosentan (Tracleer (TN)),
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
18Tracleer1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 13, 51, 84, 85, 86, 88, 210, 211 💬
19TRACLEER 125MG 56CPR RIV.1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 88 💬
20TRACLEER 62,5 mg comprimidos recubiertos con película1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
21TRACLEER 62,5MG 56CPR RIV.1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
22TRACLEER*125MG 56CPR RIV.1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 86 💬
23TRACLEER*56CPR RIV 125MG1件: Bosentan (Tracleer)2件: Bosentan (Tracleer (TN)),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 86, 88 💬
24Tracleer®----1件: 86 💬