Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Platelet activation 💬
1件: BTK 💬 D10893 💬 Acalabrutinib 2件: 46, 61 💬
2 Platelet activation 💬
1件: BTK 💬 D11478 💬 Branebrutinib 3件: 46, 49, 53 💬
3 Platelet activation 💬
1件: BTK 💬 D11457 💬 Fenebrutinib 1件: 13 💬
4 Platelet activation 💬
1件: BTK 💬 D10223 💬 Ibrutinib 3件: 28, 60, 61 💬
5 Platelet activation 💬
1件: BTK 💬 D12160 💬 Orelabrutinib 3件: 13, 61, 63 💬
6 Platelet activation 💬
1件: BTK 💬 D11422 💬 Zanubrutinib 2件: 300, 331 💬
7 Platelet activation 💬
1件: F2 💬 D09707 💬 Dabigatran 4件: 51, 85, 91, 124 💬
8 Platelet activation 💬
1件: F2 💬 D07144 💬 Dabigatran etexilate 1件: 51 💬
9 Platelet activation 💬
1件: F2 💬 D06410 💬 Thrombomodulin Alfa 1件: 85 💬
10 Platelet activation 💬
2件: FYN, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
11 Platelet activation 💬
2件: FYN, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
12 Platelet activation 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite 1件: 58 💬
13 Platelet activation 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
14 Platelet activation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
15 Platelet activation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
16 Platelet activation 💬
1件: P2RY12 💬 D00769 💬 Clopidogrel 2件: 49, 86 💬
17 Platelet activation 💬
1件: P2RY12 💬 D07729 💬 Clopidogrel 2件: 49, 86 💬
18 Platelet activation 💬
1件: P2RY12 💬 D10823 💬 Clopidogrel 2件: 49, 86 💬
19 Platelet activation 💬
1件: P2RY12 💬 D10824 💬 Clopidogrel 2件: 49, 86 💬
20 Platelet activation 💬
1件: P2RY12 💬 D09017 💬 Ticagrelor 3件: 36, 46, 85 💬
21 Platelet activation 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
22 Platelet activation 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
23 Platelet activation 💬
1件: PTGIR 💬 D02720 💬 Beraprost 1件: 86 💬
24 Platelet activation 💬
1件: PTGIR 💬 D00106 💬 Epoprostenol 1件: 86 💬
25 Platelet activation 💬
1件: PTGIR 💬 D01337 💬 Epoprostenol 1件: 86 💬
26 Platelet activation 💬
1件: PTGIR 💬 D01385 💬 Ibudilast 2件:  2 , 13 💬
27 Platelet activation 💬
1件: PTGIR 💬 D02721 💬 Iloprost 4件: 51, 84, 85, 86 💬
28 Platelet activation 💬
1件: PTGIR 💬 D10725 💬 Ralinepag 1件: 86 💬
29 Platelet activation 💬
1件: PTGIR 💬 D09994 💬 Selexipag 6件: 47, 51, 70, 84, 86, 88 💬
30 Platelet activation 💬
1件: PTGIR 💬 D06213 💬 Treprostinil 6件: 51, 84, 85, 86, 88, 210 💬
31 Platelet activation 💬
1件: PTGS1 💬 D01545 💬 Aceclofenac 1件: 46 💬
32 Platelet activation 💬
1件: PTGS1 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
33 Platelet activation 💬
1件: PTGS1 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
34 Platelet activation 💬
1件: PTGS1 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
35 Platelet activation 💬
1件: PTGS1 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
36 Platelet activation 💬
1件: PTGS1 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
37 Platelet activation 💬
1件: PTGS1 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
38 Platelet activation 💬
1件: PTGS1 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
39 Platelet activation 💬
1件: PTGS1 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
40 Platelet activation 💬
1件: PTGS1 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
41 Platelet activation 💬
1件: PTGS1 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
42 Platelet activation 💬
1件: PTGS1 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
43 Platelet activation 💬
1件: PTGS1 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
44 Platelet activation 💬
1件: PTGS1 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
45 Platelet activation 💬
1件: PTGS1 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
46 Platelet activation 💬
1件: PTGS1 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
47 Platelet activation 💬
1件: PTGS1 💬 D00132 💬 Ketoprofen 1件: 46 💬
48 Platelet activation 💬
1件: PTGS1 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
49 Platelet activation 💬
1件: PTGS1 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
50 Platelet activation 💬
1件: PTGS1 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
51 Platelet activation 💬
1件: PTGS1 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
52 Platelet activation 💬
1件: PTGS1 💬 D00428 💬 Salsalate 1件:  5  💬
53 Platelet activation 💬
1件: PTGS1 💬 D00120 💬 Sulindac 1件: 206 💬
54 Platelet activation 💬
1件: PTGS1 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
55 Platelet activation 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
56 Platelet activation 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
57 Platelet activation 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
58 Platelet activation 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
59 Platelet activation 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
60 Platelet activation 💬
1件: TBXA2R 💬 D01896 💬 Cilostazol 3件: 51, 70, 124 💬
61 Platelet activation 💬
1件: TBXA2R 💬 D04500 💬 Ifetroban 3件: 51, 86, 113 💬
62 Platelet activation 💬
1件: TBXA2R 💬 D01128 💬 Ramatroban 1件: 13 💬
63 Platelet activation 💬
1件: VWF 💬 D11160 💬 Caplacizumab 1件: 64 💬