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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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17 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Alanine, aspartate and glutamate metabolism 
 4 genes, 1 drug (DrugBank) and 14 diseases shown 
 4件: ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 2  Aldosterone synthesis and secretion 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 3  beta-Alanine metabolism 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: ABAT, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 4  Butanoate metabolism 
 4 genes, 1 drug (DrugBank) and 14 diseases shown 
 4件: ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 5  Calcium signaling pathway 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 6  Circadian entrainment 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 7  Cortisol synthesis and secretion 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 8  Cushing syndrome 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 9  GABAergic synapse 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: ABAT, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 10  GnRH secretion 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 11  MAPK signaling pathway 
 3 genes, 1 drug (DrugBank) and 14 diseases shown 
 3件: CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 12  Metabolic pathways 
 4 genes, 1 drug (DrugBank) and 14 diseases shown 
 4件: ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 13  Propanoate metabolism 
 1 gene, 1 drug (DrugBank) and 14 diseases shown 
 1件: ABAT   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 14  Taurine and hypotaurine metabolism 
 2 genes, 1 drug (DrugBank) and 14 diseases shown 
 2件: GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 15  Type I diabetes mellitus 
 2 genes, 1 drug (DrugBank) and 14 diseases shown 
 2件: GAD1, GAD2   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 16  Type II diabetes mellitus 
 1 gene, 1 drug (DrugBank) and 14 diseases shown 
 1件: CACNA1G   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 17  Valine, leucine and isoleucine degradation 
 1 gene, 1 drug (DrugBank) and 14 diseases shown 
 1件: ABAT   D00399   Valproic Acid   14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 

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