Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Yersinia infection 💬
5件: CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 Yersinia infection 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
3 Yersinia infection 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
4 Yersinia infection 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
5 Yersinia infection 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
6 Yersinia infection 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
7 Yersinia infection 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
8 Yersinia infection 💬
1件: ITGA4 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
9 Yersinia infection 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
10 Yersinia infection 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
11 Yersinia infection 💬
1件: ITGA4 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
12 Yersinia infection 💬
2件: LCK, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
13 Yersinia infection 💬
2件: LCK, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
14 Yersinia infection 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
15 Yersinia infection 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
16 Yersinia infection 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
17 Yersinia infection 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
18 Yersinia infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
19 Yersinia infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
20 Yersinia infection 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
21 Yersinia infection 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
22 Yersinia infection 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
23 Yersinia infection 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
24 Yersinia infection 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
25 Yersinia infection 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
26 Yersinia infection 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
27 Yersinia infection 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
28 Yersinia infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
29 Yersinia infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
30 Yersinia infection 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
31 Yersinia infection 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
32 Yersinia infection 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
33 Yersinia infection 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
34 Yersinia infection 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
35 Yersinia infection 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
36 Yersinia infection 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬