Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adherens junction 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
2 Bladder cancer 💬
1件: FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
3 Breast cancer 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
4 Calcium signaling pathway 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
5 Central carbon metabolism in cancer 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
6 cGMP-PKG signaling pathway 💬
1件: NPR2 💬 D11190 💬 Vosoritide 1件: 276 💬
7 Cytokine-cytokine receptor interaction 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
8 EGFR tyrosine kinase inhibitor resistance 💬
2件: FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
9 Endocytosis 💬
2件: FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
10 Gastric cancer 💬
1件: FGFR2 💬 D11589 💬 Infigratinib 1件: 276 💬
11 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
12 JAK-STAT signaling pathway 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
13 MAPK signaling pathway 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
14 Melanoma 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
15 Metabolic pathways 💬
1件: NPR2 💬 D11190 💬 Vosoritide 1件: 276 💬
16 MicroRNAs in cancer 💬
1件: FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
17 Neuroactive ligand-receptor interaction 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
18 Oxytocin signaling pathway 💬
1件: NPR2 💬 D11190 💬 Vosoritide 1件: 276 💬
19 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
20 Pathways in cancer 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
21 PI3K-Akt signaling pathway 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
22 PI3K-Akt signaling pathway 💬
1件: GHR 💬 D02691 💬 Somatotropin 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
23 Prostate cancer 💬
2件: FGFR1, FGFR2 💬 D11589 💬 Infigratinib 1件: 276 💬
24 Proteoglycans in cancer 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
25 Purine metabolism 💬
1件: NPR2 💬 D11190 💬 Vosoritide 1件: 276 💬
26 Rap1 signaling pathway 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
27 Ras signaling pathway 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
28 Regulation of actin cytoskeleton 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
29 Signaling pathways regulating pluripotency of stem cells 💬
3件: FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib 1件: 276 💬
30 Thermogenesis 💬
1件: FGFR1 💬 D11589 💬 Infigratinib 1件: 276 💬
31 Vascular smooth muscle contraction 💬
1件: NPR2 💬 D11190 💬 Vosoritide 1件: 276 💬