Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Biosynthesis of cofactors 💬
1件: ALAS1 💬 D11702 💬 Givosiran 1件: 254 💬
2 Biosynthesis of cofactors 💬
2件: ALAS1, ALAS2 💬 D10003 💬 Hemin 1件: 254 💬
3 Biosynthesis of cofactors 💬
1件: ALPL 💬 D10595 💬 Asfotase alfa 1件: 172 💬
4 Biosynthesis of cofactors 💬
2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
5 Biosynthesis of cofactors 💬
2件: DHFR, DHFR2 💬 D02115 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
6 Biosynthesis of cofactors 💬
1件: DHODH 💬 D00749 💬 Leflunomide 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
7 Biosynthesis of cofactors 💬
1件: DHODH 💬 D10172 💬 Teriflunomide 3件: 13, 25, 26 💬
8 Biosynthesis of cofactors 💬
1件: GUSB 💬 D11004 💬 Vestronidase alfa 1件: 19 💬
9 Biosynthesis of cofactors 💬
1件: HPD 💬 D05177 💬 Nitisinone 3件:  6 , 164, 241 💬
10 Biosynthesis of cofactors 💬
2件: NQO1, VKORC1 💬 D00564 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
11 Biosynthesis of cofactors 💬
2件: NQO1, VKORC1 💬 D01280 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
12 Biosynthesis of cofactors 💬
2件: NQO1, VKORC1 💬 D08682 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
13 Biosynthesis of cofactors 💬
1件: VKORC1 💬 D08354 💬 Phenindione 1件: 65 💬