Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Salivary secretion 💬
1件: ADRA1A 💬 D01692 💬 Alfuzosin 1件: 13 💬
2 Salivary secretion 💬
1件: ADRA1A 💬 D07124 💬 Alfuzosin 1件: 13 💬
3 Salivary secretion 💬
1件: ADRA1A 💬 D01965 💬 Silodosin 2件:  6 , 13 💬
4 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin 2件: 57, 67 💬
5 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin 2件: 57, 67 💬
6 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D02268 💬 Ergoloid mesylate 2件:  6 , 206 💬
7 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D08064 💬 Ifenprodil 1件: 85 💬
8 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D00680 💬 Methylergometrine 3件: 118, 280, 288 💬
9 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D08207 💬 Methylergometrine 3件: 118, 280, 288 💬
10 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D01307 💬 Midodrine 3件:  6 , 17, 58 💬
11 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D08220 💬 Midodrine 3件:  6 , 17, 58 💬
12 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine 2件:  2 ,  8  💬
13 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D06623 💬 Olanzapine 2件:  2 ,  8  💬
14 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D00511 💬 Phenylephrine 1件: 22 💬
15 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
16 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D00610 💬 Terazosin 1件:  6  💬
17 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 D08569 💬 Terazosin 1件:  6  💬
18 Salivary secretion 💬
4件: ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
19 Salivary secretion 💬
4件: ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
20 Salivary secretion 💬
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol 5件:  6 , 57, 86, 113, 210 💬
21 Salivary secretion 💬
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol 5件:  6 , 57, 86, 113, 210 💬
22 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D02349 💬 Dipivefrin 1件:  6  💬
23 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
24 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00124 💬 Ephedrine 1件: 11 💬
25 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00095 💬 Epinephrine 3件: 46, 70, 96 💬
26 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00996 💬 Epinephrine 3件: 46, 70, 96 💬
27 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D02149 💬 Epinephrine 3件: 46, 70, 96 💬
28 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 1件: 22 💬
29 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D05206 💬 Norepinephrine 1件: 22 💬
30 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00485 💬 Pseudoephedrine 1件: 17 💬
31 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D05648 💬 Pseudoephedrine 1件: 17 💬
32 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D05649 💬 Pseudoephedrine 1件: 17 💬
33 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D08449 💬 Pseudoephedrine 1件: 17 💬
34 Salivary secretion 💬
1件: ADRB1 💬 D00235 💬 Atenolol 1件: 167 💬
35 Salivary secretion 💬
1件: ADRB1 💬 D00634 💬 Bisoprolol 3件: 67, 86, 113 💬
36 Salivary secretion 💬
1件: ADRB1 💬 D02342 💬 Bisoprolol 3件: 67, 86, 113 💬
37 Salivary secretion 💬
1件: ADRB1 💬 D07660 💬 Celiprolol 1件: 168 💬
38 Salivary secretion 💬
1件: ADRB1 💬 D00632 💬 Dobutamine 3件: 57, 58, 215 💬
39 Salivary secretion 💬
1件: ADRB1 💬 D03879 💬 Dobutamine 3件: 57, 58, 215 💬
40 Salivary secretion 💬
1件: ADRB1 💬 D03880 💬 Dobutamine 3件: 57, 58, 215 💬
41 Salivary secretion 💬
1件: ADRB1 💬 D03881 💬 Dobutamine 3件: 57, 58, 215 💬
42 Salivary secretion 💬
1件: ADRB1 💬 D00644 💬 Esmolol 1件: 58 💬
43 Salivary secretion 💬
1件: ADRB1 💬 D07916 💬 Esmolol 1件: 58 💬
44 Salivary secretion 💬
1件: ADRB1 💬 D00601 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
45 Salivary secretion 💬
1件: ADRB1 💬 D02358 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
46 Salivary secretion 💬
1件: ADRB1 💬 D05011 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
47 Salivary secretion 💬
1件: ADRB1 💬 D05127 💬 Nebivolol 4件: 17, 85, 113, 167 💬
48 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 D00432 💬 Nadolol 1件:  6  💬
49 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 D00378 💬 Timolol 2件: 157, 227 💬
50 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 D00603 💬 Timolol 2件: 157, 227 💬
51 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 D08600 💬 Timolol 2件: 157, 227 💬
52 Salivary secretion 💬
3件: ADRB1, ADRB2, ADRB3 💬 D00483 💬 Propranolol 7件:  6 , 158, 167, 215, 227, 278, 296 💬
53 Salivary secretion 💬
3件: ADRB1, ADRB2, ADRB3 💬 D08443 💬 Propranolol 7件:  6 , 158, 167, 215, 227, 278, 296 💬
54 Salivary secretion 💬
1件: ADRB2 💬 D07713 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬
55 Salivary secretion 💬
1件: ADRB2 💬 D01373 💬 Formoterol 3件: 85, 228, 299 💬
56 Salivary secretion 💬
1件: ADRB2 💬 D05277 💬 Formoterol 3件: 85, 228, 299 💬
57 Salivary secretion 💬
1件: ADRB2 💬 D07990 💬 Formoterol 3件: 85, 228, 299 💬
58 Salivary secretion 💬
1件: ADRB2 💬 D08092 💬 Isoxsuprine 1件: 13 💬
59 Salivary secretion 💬
1件: ADRB2 💬 D08124 💬 Levosalbutamol 1件: 49 💬
60 Salivary secretion 💬
1件: ADRB2 💬 D02147 💬 Salbutamol 14件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
61 Salivary secretion 💬
1件: ADRB2 💬 D00687 💬 Salmeterol 1件: 299 💬
62 Salivary secretion 💬
1件: ADRB2 💬 D05792 💬 Salmeterol 1件: 299 💬
63 Salivary secretion 💬
1件: ADRB2 💬 D00688 💬 Terbutaline 1件: 118 💬
64 Salivary secretion 💬
1件: ADRB2 💬 D08570 💬 Terbutaline 1件: 118 💬
65 Salivary secretion 💬
1件: ADRB2 💬 D02151 💬 Tulobuterol 1件:  6  💬
66 Salivary secretion 💬
1件: ADRB3 💬 D09535 💬 Mirabegron 4件:  6 , 13, 53, 226 💬
67 Salivary secretion 💬
2件: AMY2A, AMY2B 💬 D00216 💬 Acarbose 1件: 298 💬
68 Salivary secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin 1件: 299 💬
69 Salivary secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin 3件:  8 , 46, 210 💬
70 Salivary secretion 💬
1件: CD38 💬 D10777 💬 Daratumumab 5件: 16, 28, 49, 63, 222 💬
71 Salivary secretion 💬
1件: CD38 💬 D11050 💬 Isatuximab 2件: 28, 61 💬
72 Salivary secretion 💬
1件: CD38 💬 D11945 💬 Mezagitamab 1件: 66 💬
73 Salivary secretion 💬
1件: CHRM3 💬 D00113 💬 Atropine 2件:  2 , 299 💬
74 Salivary secretion 💬
1件: CHRM3 💬 D01077 💬 Atropine 2件:  2 , 299 💬
75 Salivary secretion 💬
1件: CHRM3 💬 D02069 💬 Atropine 2件:  2 , 299 💬
76 Salivary secretion 💬
1件: CHRM3 💬 D03011 💬 Atropine 2件:  2 , 299 💬
77 Salivary secretion 💬
1件: CHRM3 💬 D03814 💬 Atropine 2件:  2 , 299 💬
78 Salivary secretion 💬
1件: CHRM3 💬 D01000 💬 Bethanechol 1件: 98 💬
79 Salivary secretion 💬
1件: CHRM3 💬 D11383 💬 Blarcamesine 1件: 156 💬
80 Salivary secretion 💬
1件: CHRM3 💬 D00661 💬 Cevimeline 1件: 53 💬
81 Salivary secretion 💬
1件: CHRM3 💬 D07667 💬 Cevimeline 1件: 53 💬
82 Salivary secretion 💬
1件: CHRM3 💬 D00270 💬 Chlorpromazine 1件: 254 💬
83 Salivary secretion 💬
1件: CHRM3 💬 D00789 💬 Chlorpromazine 1件: 254 💬
84 Salivary secretion 💬
1件: CHRM3 💬 D03274 💬 Chlorpromazine 1件: 254 💬
85 Salivary secretion 💬
1件: CHRM3 💬 D04034 💬 Chlorpromazine 1件: 254 💬
86 Salivary secretion 💬
1件: CHRM3 💬 D01699 💬 Darifenacin 2件:  6 , 13 💬
87 Salivary secretion 💬
1件: CHRM3 💬 D03654 💬 Darifenacin 2件:  6 , 13 💬
88 Salivary secretion 💬
1件: CHRM3 💬 D07226 💬 Fesoterodine 1件:  6  💬
89 Salivary secretion 💬
1件: CHRM3 💬 D02212 💬 Ipratropium 2件:  6 , 86 💬
90 Salivary secretion 💬
1件: CHRM3 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
91 Salivary secretion 💬
1件: CHRM3 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
92 Salivary secretion 💬
1件: CHRM3 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
93 Salivary secretion 💬
1件: CHRM3 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
94 Salivary secretion 💬
1件: CHRM3 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
95 Salivary secretion 💬
1件: CHRM3 💬 D00481 💬 Propantheline 1件: 26 💬
96 Salivary secretion 💬
1件: CHRM3 💬 D08441 💬 Propiverine 1件: 226 💬
97 Salivary secretion 💬
1件: CHRM3 💬 D00765 💬 Rocuronium 1件: 296 💬
98 Salivary secretion 💬
1件: CHRM3 💬 D00138 💬 Scopolamine 1件:  2  💬
99 Salivary secretion 💬
1件: CHRM3 💬 D01269 💬 Solifenacin 3件:  6 , 13, 53 💬
100 Salivary secretion 💬
1件: CHRM3 💬 D08522 💬 Solifenacin 3件:  6 , 13, 53 💬
101 Salivary secretion 💬
1件: CHRM3 💬 D00646 💬 Tolterodine 2件: 17, 53 💬
102 Salivary secretion 💬
1件: CHRM3 💬 D01148 💬 Tolterodine 2件: 17, 53 💬
103 Salivary secretion 💬
1件: CHRM3 💬 D00787 💬 Trihexyphenidyl 2件:  5 ,  6  💬
104 Salivary secretion 💬
1件: CHRM3 💬 D08638 💬 Trihexyphenidyl 2件:  5 ,  6  💬
105 Salivary secretion 💬
1件: CHRM3 💬 D00397 💬 Tropicamide 3件:  6 , 13, 19 💬
106 Salivary secretion 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite 1件: 58 💬
107 Salivary secretion 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
108 Salivary secretion 💬
1件: SLC12A2 💬 D00247 💬 Bumetanide 2件:  6 , 158 💬
109 Salivary secretion 💬
1件: SLC12A2 💬 D00331 💬 Furosemide 1件:  6  💬