Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 TGF-beta signaling pathway 💬
1件: ACVR2A 💬 D09670 💬 Sotatercept 2件: 86, 284 💬
2 TGF-beta signaling pathway 💬
2件: ACVR2A, ACVR2B 💬 D10620 💬 Bimagrumab 1件: 15 💬
3 TGF-beta signaling pathway 💬
1件: BMPR2 💬 D03779 💬 Dibotermin alfa 1件: 34 💬
4 TGF-beta signaling pathway 💬
1件: IFNG 💬 D11120 💬 Emapalumab 2件: 49, 107 💬
5 TGF-beta signaling pathway 💬
1件: IFNG 💬 D04242 💬 Fontolizumab 1件: 46 💬
6 TGF-beta signaling pathway 💬
1件: RGMA 💬 D11355 💬 Elezanumab 1件: 13 💬
7 TGF-beta signaling pathway 💬
1件: ROCK1 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
8 TGF-beta signaling pathway 💬
1件: SMAD7 💬 D10956 💬 Mongersen 2件: 96, 97 💬
9 TGF-beta signaling pathway 💬
3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
10 TGF-beta signaling pathway 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
11 TGF-beta signaling pathway 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
12 TGF-beta signaling pathway 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
13 TGF-beta signaling pathway 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
14 TGF-beta signaling pathway 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
15 TGF-beta signaling pathway 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
16 TGF-beta signaling pathway 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
17 TGF-beta signaling pathway 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
18 TGF-beta signaling pathway 💬
1件: TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
19 TGF-beta signaling pathway 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
20 TGF-beta signaling pathway 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬