Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Taste transduction 💬
1件: CACNA1C 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 Taste transduction 💬
1件: CACNA1C 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
3 Taste transduction 💬
1件: CACNA1C 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
4 Taste transduction 💬
1件: CACNA1C 💬 D01173 💬 Cilnidipine 1件: 67 💬
5 Taste transduction 💬
1件: CACNA1C 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
6 Taste transduction 💬
1件: CACNA1C 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
7 Taste transduction 💬
1件: CACNA1C 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
8 Taste transduction 💬
1件: CACNA1C 💬 D00349 💬 Isradipine 1件:  6  💬
9 Taste transduction 💬
1件: CACNA1C 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
10 Taste transduction 💬
1件: CACNA1C 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
11 Taste transduction 💬
1件: CACNA1C 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
12 Taste transduction 💬
1件: CACNA1C 💬 D01908 💬 Nilvadipine 1件: 90 💬
13 Taste transduction 💬
1件: CACNA1C 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
14 Taste transduction 💬
1件: CACNA1C 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
15 Taste transduction 💬
1件: CACNA1C 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
16 Taste transduction 💬
1件: CACNA1C 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
17 Taste transduction 💬
2件: CACNA1C, CHRM3 💬 D08441 💬 Propiverine 1件: 226 💬
18 Taste transduction 💬
10件: CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
19 Taste transduction 💬
1件: CHRM3 💬 D00113 💬 Atropine 2件:  2 , 299 💬
20 Taste transduction 💬
1件: CHRM3 💬 D01077 💬 Atropine 2件:  2 , 299 💬
21 Taste transduction 💬
1件: CHRM3 💬 D02069 💬 Atropine 2件:  2 , 299 💬
22 Taste transduction 💬
1件: CHRM3 💬 D03011 💬 Atropine 2件:  2 , 299 💬
23 Taste transduction 💬
1件: CHRM3 💬 D03814 💬 Atropine 2件:  2 , 299 💬
24 Taste transduction 💬
1件: CHRM3 💬 D01000 💬 Bethanechol 1件: 98 💬
25 Taste transduction 💬
1件: CHRM3 💬 D11383 💬 Blarcamesine 1件: 156 💬
26 Taste transduction 💬
1件: CHRM3 💬 D00661 💬 Cevimeline 1件: 53 💬
27 Taste transduction 💬
1件: CHRM3 💬 D07667 💬 Cevimeline 1件: 53 💬
28 Taste transduction 💬
1件: CHRM3 💬 D00270 💬 Chlorpromazine 1件: 254 💬
29 Taste transduction 💬
1件: CHRM3 💬 D00789 💬 Chlorpromazine 1件: 254 💬
30 Taste transduction 💬
1件: CHRM3 💬 D03274 💬 Chlorpromazine 1件: 254 💬
31 Taste transduction 💬
1件: CHRM3 💬 D04034 💬 Chlorpromazine 1件: 254 💬
32 Taste transduction 💬
1件: CHRM3 💬 D01699 💬 Darifenacin 2件:  6 , 13 💬
33 Taste transduction 💬
1件: CHRM3 💬 D03654 💬 Darifenacin 2件:  6 , 13 💬
34 Taste transduction 💬
1件: CHRM3 💬 D07226 💬 Fesoterodine 1件:  6  💬
35 Taste transduction 💬
1件: CHRM3 💬 D02212 💬 Ipratropium 2件:  6 , 86 💬
36 Taste transduction 💬
1件: CHRM3 💬 D00465 💬 Oxybutynin 3件:  6 , 13, 53 💬
37 Taste transduction 💬
1件: CHRM3 💬 D00722 💬 Oxybutynin 3件:  6 , 13, 53 💬
38 Taste transduction 💬
1件: CHRM3 💬 D00525 💬 Pilocarpine 3件:  6 , 53, 299 💬
39 Taste transduction 💬
1件: CHRM3 💬 D02200 💬 Pilocarpine 3件:  6 , 53, 299 💬
40 Taste transduction 💬
1件: CHRM3 💬 D05478 💬 Pilocarpine 3件:  6 , 53, 299 💬
41 Taste transduction 💬
1件: CHRM3 💬 D00481 💬 Propantheline 1件: 26 💬
42 Taste transduction 💬
1件: CHRM3 💬 D00765 💬 Rocuronium 1件: 296 💬
43 Taste transduction 💬
1件: CHRM3 💬 D00138 💬 Scopolamine 1件:  2  💬
44 Taste transduction 💬
1件: CHRM3 💬 D01269 💬 Solifenacin 3件:  6 , 13, 53 💬
45 Taste transduction 💬
1件: CHRM3 💬 D08522 💬 Solifenacin 3件:  6 , 13, 53 💬
46 Taste transduction 💬
1件: CHRM3 💬 D00646 💬 Tolterodine 2件: 17, 53 💬
47 Taste transduction 💬
1件: CHRM3 💬 D01148 💬 Tolterodine 2件: 17, 53 💬
48 Taste transduction 💬
1件: CHRM3 💬 D00787 💬 Trihexyphenidyl 2件:  5 ,  6  💬
49 Taste transduction 💬
1件: CHRM3 💬 D08638 💬 Trihexyphenidyl 2件:  5 ,  6  💬
50 Taste transduction 💬
1件: CHRM3 💬 D00397 💬 Tropicamide 3件:  6 , 13, 19 💬
51 Taste transduction 💬
2件: GABBR1, GABBR2 💬 D09791 💬 Arbaclofen 2件: 13, 206 💬
52 Taste transduction 💬
2件: GABBR1, GABBR2 💬 D08861 💬 Arbaclofen Placarbil 1件: 13 💬
53 Taste transduction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
54 Taste transduction 💬
1件: GABRA1 💬 D00548 💬 Etomidate 1件:  6  💬
55 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00225 💬 Alprazolam 2件:  8 , 75 💬
56 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D11149 💬 Brexanolone 1件: 205 💬
57 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00267 💬 Chlordiazepoxide 1件: 46 💬
58 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00693 💬 Chlordiazepoxide 1件: 46 💬
59 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D01253 💬 Clobazam 2件: 140, 144 💬
60 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00280 💬 Clonazepam 1件:  6  💬
61 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D07784 💬 Delorazepam 3件:  6 , 46, 97 💬
62 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00293 💬 Diazepam 3件: 46, 155, 298 💬
63 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D02624 💬 Eszopiclone 3件:  6 , 13, 46 💬
64 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D01514 💬 Etizolam 1件: 46 💬
65 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00697 💬 Flumazenil 5件:  6 , 13, 17, 18, 206 💬
66 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D04282 💬 Gaboxadol 2件: 201, 206 💬
67 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D04300 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
68 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00365 💬 Lorazepam 2件: 36, 231 💬
69 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00550 💬 Midazolam 12件:  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
70 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00696 💬 Midazolam 12件:  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
71 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D05028 💬 Midazolam 12件:  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
72 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00549 💬 Propofol 10件:  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
73 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00706 💬 Zolpidem 3件:  5 ,  6 , 46 💬
74 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D08690 💬 Zolpidem 3件:  5 ,  6 , 46 💬
75 Taste transduction 💬
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D01372 💬 Zopiclone 1件:  6  💬
76 Taste transduction 💬
1件: HTR1A 💬 D01164 💬 Aripiprazole 2件:  6 , 206 💬
77 Taste transduction 💬
1件: HTR1A 💬 D00702 💬 Buspirone 3件:  6 , 51, 179 💬
78 Taste transduction 💬
1件: HTR1A 💬 D07593 💬 Buspirone 3件:  6 , 51, 179 💬
79 Taste transduction 💬
1件: HTR1A 💬 D09997 💬 Cariprazine 1件: 21 💬
80 Taste transduction 💬
1件: HTR1A 💬 D09397 💬 Pardoprunox 1件:  6  💬
81 Taste transduction 💬
6件: HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 D10184 💬 Vortioxetine 1件:  6  💬
82 Taste transduction 💬
2件: HTR1B, HTR1D 💬 D00415 💬 Zolmitriptan 1件:  6  💬
83 Taste transduction 💬
1件: HTR3A 💬 D00274 💬 Cisapride 1件: 13 💬
84 Taste transduction 💬
1件: HTR3A 💬 D02092 💬 Cisapride 1件: 13 💬
85 Taste transduction 💬
5件: HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 D00283 💬 Clozapine 1件:  6  💬
86 Taste transduction 💬
5件: HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 D00456 💬 Ondansetron 4件:  6 , 97, 107, 231 💬
87 Taste transduction 💬
5件: HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 D00678 💬 Ondansetron 4件:  6 , 97, 107, 231 💬
88 Taste transduction 💬
1件: P2RX3 💬 D11349 💬 Gefapixant 2件: 85, 226 💬
89 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D00227 💬 Aminophylline 1件: 63 💬
90 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D05429 💬 Aminophylline 1件: 63 💬
91 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D07546 💬 Bucladesine 1件: 246 💬
92 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D00718 💬 Flavoxate 1件: 226 💬
93 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D07961 💬 Flavoxate 1件: 226 💬
94 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D00371 💬 Theophylline 2件: 236, 299 💬
95 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D01712 💬 Theophylline 2件: 236, 299 💬
96 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D02017 💬 Theophylline 2件: 236, 299 💬
97 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D06103 💬 Theophylline 2件: 236, 299 💬
98 Taste transduction 💬
3件: PDE1A, PDE1B, PDE1C 💬 D06104 💬 Theophylline 2件: 236, 299 💬
99 Taste transduction 💬
1件: PDE1B 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
100 Taste transduction 💬
1件: PDE1B 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
101 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
102 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
103 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D01450 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
104 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D07552 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
105 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00252 💬 Carbamazepine 2件: 13, 231 💬
106 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D03492 💬 Cibenzoline 1件: 58 💬
107 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D11155 💬 Eleclazine 1件: 58 💬
108 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00638 💬 Flecainide 1件:  6  💬
109 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D07962 💬 Flecainide 1件:  6  💬
110 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00354 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
111 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D01287 💬 Levobupivacaine 1件: 46 💬
112 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D08116 💬 Levobupivacaine 1件: 46 💬
113 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00358 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
114 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D02086 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
115 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D08127 💬 Lidocaine 13件:  6 , 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256 💬
116 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00639 💬 Mexiletine 5件:  1 ,  2 , 10, 113, 114 💬
117 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D08215 💬 Mexiletine 5件:  1 ,  2 , 10, 113, 114 💬
118 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00533 💬 Oxcarbazepine 1件: 13 💬
119 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D01768 💬 Oxybuprocaine 1件:  6  💬
120 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D08319 💬 Oxybuprocaine 1件:  6  💬
121 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00512 💬 Phenytoin 1件: 13 💬
122 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D02103 💬 Phenytoin 1件: 13 💬
123 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00642 💬 Quinidine 3件:  2 ,  8 , 13 💬
124 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00643 💬 Quinidine 3件:  2 ,  8 , 13 💬
125 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D02272 💬 Quinidine 3件:  2 ,  8 , 13 💬
126 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D08458 💬 Quinidine 3件:  2 ,  8 , 13 💬
127 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D04048 💬 Ropivacaine 3件: 36, 46, 70 💬
128 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D08490 💬 Ropivacaine 3件: 36, 46, 70 💬
129 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D05775 💬 Rufinamide 1件: 144 💬
130 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 D00538 💬 Zonisamide 1件:  6  💬
131 Taste transduction 💬
2件: SCN3A, SCN9A 💬 D07299 💬 Lacosamide 3件:  2 , 46, 149 💬
132 Taste transduction 💬
3件: SCNN1A, SCNN1B, SCNN1G 💬 D00649 💬 Amiloride 4件: 13, 67, 225, 299 💬
133 Taste transduction 💬
3件: SCNN1A, SCNN1B, SCNN1G 💬 D07447 💬 Amiloride 4件: 13, 67, 225, 299 💬
134 Taste transduction 💬
2件: TAS1R2, TAS1R3 💬 D02381 💬 Aspartame 5件:  6 , 13, 67, 86, 230 💬