Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Calcium signaling pathway 💬
8件: ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
2 Calcium signaling pathway 💬
8件: CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
3 Calcium signaling pathway 💬
3件: HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
4 Calcium signaling pathway 💬
3件: HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone 1件:  2  💬
5 Calcium signaling pathway 💬
2件: HTR2A, HTR2C 💬 Clozapine 💬 Clozapine 1件:  6  💬
6 Calcium signaling pathway 💬
2件: HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
7 Calcium signaling pathway 💬
1件: HTR2C 💬 Agomelatine 💬 Agomelatine 1件:  6  💬
8 Gap junction 💬
4件: DRD2, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
9 Gap junction 💬
4件: DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
10 Gap junction 💬
4件: DRD2, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
11 Gap junction 💬
3件: HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone 1件:  2  💬
12 Gap junction 💬
2件: HTR2A, HTR2C 💬 Clozapine 💬 Clozapine 1件:  6  💬
13 Gap junction 💬
2件: HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
14 Gap junction 💬
1件: HTR2C 💬 Agomelatine 💬 Agomelatine 1件:  6  💬
15 Inflammatory mediator regulation of TRP channels 💬
4件: HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
16 Inflammatory mediator regulation of TRP channels 💬
4件: HRH1, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
17 Inflammatory mediator regulation of TRP channels 💬
3件: HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
18 Inflammatory mediator regulation of TRP channels 💬
3件: HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone 1件:  2  💬
19 Inflammatory mediator regulation of TRP channels 💬
2件: HTR2A, HTR2C 💬 Clozapine 💬 Clozapine 1件:  6  💬
20 Inflammatory mediator regulation of TRP channels 💬
2件: HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
21 Inflammatory mediator regulation of TRP channels 💬
1件: HTR2C 💬 Agomelatine 💬 Agomelatine 1件:  6  💬
22 Neuroactive ligand-receptor interaction 💬
11件: ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
23 Neuroactive ligand-receptor interaction 💬
13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
24 Neuroactive ligand-receptor interaction 💬
6件: ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C 💬 Clozapine 💬 Clozapine 1件:  6  💬
25 Neuroactive ligand-receptor interaction 💬
4件: DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
26 Neuroactive ligand-receptor interaction 💬
3件: HTR1D, HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
27 Neuroactive ligand-receptor interaction 💬
3件: HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone 1件:  2  💬
28 Neuroactive ligand-receptor interaction 💬
3件: HTR2C, MTNR1A, MTNR1B 💬 Agomelatine 💬 Agomelatine 1件:  6  💬
29 Serotonergic synapse 💬
4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
30 Serotonergic synapse 💬
3件: HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
31 Serotonergic synapse 💬
3件: HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
32 Serotonergic synapse 💬
4件: HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
33 Serotonergic synapse 💬
4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬 Trazodone 💬 Trazodone 1件:  2  💬
34 Serotonergic synapse 💬
7件: HTR2A, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Clozapine 💬 Clozapine 1件:  6  💬
35 Serotonergic synapse 💬
1件: HTR2C 💬 Agomelatine 💬 Agomelatine 1件:  6  💬