Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
2 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
3 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
4 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
5 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
6 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
7 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
8 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
9 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
10 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
11 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
12 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
13 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
14 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
15 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
16 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
17 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
18 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
19 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
20 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
21 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
22 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
23 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
24 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
25 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
26 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
27 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
28 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
29 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
30 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
31 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
32 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
33 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
34 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
35 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
36 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|