Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
2 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
3 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
4 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
5 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
6 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
7 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
8 cGMP-PKG signaling pathway 💬
4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
9 cGMP-PKG signaling pathway 💬
4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
10 cGMP-PKG signaling pathway 💬
4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
11 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
12 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
13 cGMP-PKG signaling pathway 💬
3件: PDE2A, PDE3A, PDE3B 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
14 cGMP-PKG signaling pathway 💬
3件: PDE2A, PDE3A, PDE3B 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
15 Metabolic pathways 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
16 Metabolic pathways 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
17 Metabolic pathways 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
18 Metabolic pathways 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
19 Metabolic pathways 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
20 Metabolic pathways 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
21 Metabolic pathways 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
22 Morphine addiction 💬
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
23 Morphine addiction 💬
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
24 Morphine addiction 💬
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
25 Morphine addiction 💬
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
26 Morphine addiction 💬
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
27 Morphine addiction 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
28 Morphine addiction 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
29 Olfactory transduction 💬
4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
30 Olfactory transduction 💬
4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
31 Olfactory transduction 💬
4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
32 Olfactory transduction 💬
4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
33 Olfactory transduction 💬
4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
34 Olfactory transduction 💬
2件: PDE1B, PDE2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
35 Olfactory transduction 💬
2件: PDE1B, PDE2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
36 Purine metabolism 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
37 Purine metabolism 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
38 Purine metabolism 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
39 Purine metabolism 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
40 Purine metabolism 💬
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
41 Purine metabolism 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
42 Purine metabolism 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬