Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Salivary secretion 💬
1件: ADRA1A 💬 Alfuzosin 💬 Alfuzosin 1件: 13 💬 💬
2 Salivary secretion 💬
1件: ADRA1A 💬 Silodosin 💬 Silodosin 2件:  6 , 13 💬 💬
3 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin 2件: 57, 67 💬 💬
4 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine 1件: 280 💬 💬
5 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine 3件:  6 , 17, 58 💬 💬
6 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬 💬
7 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine 1件: 22 💬 💬
8 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin 1件: 13 💬 💬
9 Salivary secretion 💬
3件: ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin 1件:  6  💬 💬
10 Salivary secretion 💬
4件: ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬 💬
11 Salivary secretion 💬
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬 💬
12 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin 1件:  6  💬 💬
13 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬 💬
14 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine 1件: 11 💬 💬
15 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine 3件: 46, 70, 96 💬 💬
16 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬 💬
17 Salivary secretion 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine 1件: 17 💬 💬
18 Salivary secretion 💬
1件: ADRB1 💬 Atenolol 💬 Atenolol 1件: 167 💬 💬
19 Salivary secretion 💬
1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬 💬
20 Salivary secretion 💬
1件: ADRB1 💬 Celiprolol 💬 Celiprolol 1件: 168 💬 💬
21 Salivary secretion 💬
1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬 💬
22 Salivary secretion 💬
1件: ADRB1 💬 Esmolol 💬 Esmolol 1件: 58 💬 💬
23 Salivary secretion 💬
1件: ADRB1 💬 Metoprolol 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬 💬
24 Salivary secretion 💬
1件: ADRB1 💬 Nebivolol 💬 Nebivolol 4件: 17, 85, 113, 167 💬 💬
25 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 Nadolol 💬 Nadolol 1件:  6  💬 💬
26 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 Timolol 💬 Timolol 2件: 157, 227 💬 💬
27 Salivary secretion 💬
2件: ADRB1, ADRB2 💬 Timolol 💬 Timolol 2件: 157, 227 💬 💬
28 Salivary secretion 💬
3件: ADRB1, ADRB2, ADRB3 💬 Propranolol 💬 Propranolol 6件:  6 , 158, 167, 227, 278, 296 💬 💬
29 Salivary secretion 💬
1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬 💬
30 Salivary secretion 💬
1件: ADRB2 💬 Formoterol 💬 Formoterol 3件: 85, 228, 299 💬 💬
31 Salivary secretion 💬
1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬 💬
32 Salivary secretion 💬
1件: ADRB2 💬 Levosalbutamol 💬 Levosalbutamol 1件: 49 💬 💬
33 Salivary secretion 💬
1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
34 Salivary secretion 💬
1件: ADRB2 💬 Salmeterol 💬 Salmeterol 1件: 299 💬 💬
35 Salivary secretion 💬
1件: ADRB2 💬 Terbutaline 💬 Terbutaline 1件: 118 💬 💬
36 Salivary secretion 💬
1件: ADRB2 💬 Tulobuterol 💬 Tulobuterol 1件:  6  💬 💬
37 Salivary secretion 💬
1件: ADRB3 💬 Mirabegron 💬 Mirabegron 4件:  6 , 13, 53, 226 💬 💬
38 Salivary secretion 💬
2件: AMY2A, AMY2B 💬 Acarbose 💬 Acarbose 1件: 298 💬 💬
39 Salivary secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin 1件: 299 💬 💬
40 Salivary secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin 3件:  8 , 46, 210 💬 💬
41 Salivary secretion 💬
1件: CD38 💬 Daratumumab 💬 Daratumumab 5件: 13, 28, 48, 49, 63 💬 💬
42 Salivary secretion 💬
1件: CD38 💬 Isatuximab 💬 Isatuximab 3件: 28, 61, 283 💬 💬
43 Salivary secretion 💬
1件: CD38 💬 Mezagitamab 💬 Mezagitamab 2件: 63, 66 💬 💬
44 Salivary secretion 💬
1件: CHRM3 💬 Atropine 💬 Atropine 2件:  2 , 299 💬 💬
45 Salivary secretion 💬
1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
46 Salivary secretion 💬
1件: CHRM3 💬 Cevimeline 💬 Cevimeline 1件: 53 💬 💬
47 Salivary secretion 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬 💬
48 Salivary secretion 💬
1件: CHRM3 💬 Darifenacin 💬 Darifenacin 2件:  6 , 13 💬 💬
49 Salivary secretion 💬
1件: CHRM3 💬 Fesoterodine 💬 Fesoterodine 1件:  6  💬 💬
50 Salivary secretion 💬
1件: CHRM3 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬 💬
51 Salivary secretion 💬
1件: CHRM3 💬 Pilocarpine 💬 Pilocarpine 3件:  6 , 53, 299 💬 💬
52 Salivary secretion 💬
1件: CHRM3 💬 Propiverine 💬 Propiverine 1件: 226 💬 💬
53 Salivary secretion 💬
1件: CHRM3 💬 Scopolamine 💬 Scopolamine 1件:  2  💬 💬
54 Salivary secretion 💬
1件: CHRM3 💬 Solifenacin 💬 Solifenacin 3件:  6 , 13, 53 💬 💬
55 Salivary secretion 💬
1件: CHRM3 💬 Tolterodine 💬 Tolterodine 2件: 17, 53 💬 💬
56 Salivary secretion 💬
1件: CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl 2件:  5 ,  6  💬 💬
57 Salivary secretion 💬
1件: CHRM3 💬 Tropicamide 💬 Tropicamide 1件:  6  💬 💬
58 Salivary secretion 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite 1件: 58 💬 💬
59 Salivary secretion 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬 💬
60 Salivary secretion 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
61 Salivary secretion 💬
1件: SLC12A2 💬 Bumetanide 💬 Bumetanide 2件:  6 , 158 💬 💬
62 Salivary secretion 💬
1件: SLC12A2 💬 Furosemide 💬 Furosemide 2件:  6 , 86 💬 💬