Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Gastric acid secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin 1件: 299 💬
2 Gastric acid secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin 3件:  8 , 46, 210 💬
3 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Dexlansoprazole 💬 Dexlansoprazole 1件: 98 💬
4 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
5 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole 7件: 63, 71, 85, 98, 166, 222, 299 💬
6 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Omeprazole 💬 Omeprazole 14件:  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
7 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Pantoprazole 💬 Pantoprazole 2件: 13, 65 💬
8 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Rabeprazole 💬 Rabeprazole 2件:  2 , 51 💬
9 Gastric acid secretion 💬
2件: ATP4A, ATP4B 💬 Vonoprazan 💬 Vonoprazan 2件: 63, 98 💬
10 Gastric acid secretion 💬
1件: CA2 💬 Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬
11 Gastric acid secretion 💬
1件: CA2 💬 Dichlorphenamide 💬 Diclofenamide 1件: 114 💬
12 Gastric acid secretion 💬
1件: CA2 💬 Dorzolamide 💬 Dorzolamide 1件: 90 💬
13 Gastric acid secretion 💬
1件: CA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
14 Gastric acid secretion 💬
1件: CCKBR 💬 Proglumide 💬 Proglumide 1件: 298 💬
15 Gastric acid secretion 💬
1件: CFTR 💬 Deutivacaftor 💬 Deutivacaftor 1件: 299 💬
16 Gastric acid secretion 💬
1件: CFTR 💬 Elexacaftor 💬 Elexacaftor 1件: 299 💬
17 Gastric acid secretion 💬
1件: CFTR 💬 Galicaftor 💬 Galicaftor 1件: 299 💬
18 Gastric acid secretion 💬
1件: CFTR 💬 Ivacaftor 💬 Ivacaftor 1件: 299 💬
19 Gastric acid secretion 💬
1件: CFTR 💬 Lumacaftor 💬 Lumacaftor 1件: 299 💬
20 Gastric acid secretion 💬
1件: CFTR 💬 Tezacaftor 💬 Tezacaftor 1件: 299 💬
21 Gastric acid secretion 💬
1件: CHRM3 💬 Atropine 💬 Atropine 2件:  2 , 299 💬
22 Gastric acid secretion 💬
1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬
23 Gastric acid secretion 💬
1件: CHRM3 💬 Cevimeline 💬 Cevimeline 1件: 53 💬
24 Gastric acid secretion 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
25 Gastric acid secretion 💬
1件: CHRM3 💬 Darifenacin 💬 Darifenacin 2件:  6 , 13 💬
26 Gastric acid secretion 💬
1件: CHRM3 💬 Fesoterodine 💬 Fesoterodine 1件:  6  💬
27 Gastric acid secretion 💬
1件: CHRM3 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬
28 Gastric acid secretion 💬
1件: CHRM3 💬 Pilocarpine 💬 Pilocarpine 3件:  6 , 53, 299 💬
29 Gastric acid secretion 💬
1件: CHRM3 💬 Propiverine 💬 Propiverine 1件: 226 💬
30 Gastric acid secretion 💬
1件: CHRM3 💬 Scopolamine 💬 Scopolamine 1件:  2  💬
31 Gastric acid secretion 💬
1件: CHRM3 💬 Solifenacin 💬 Solifenacin 3件:  6 , 13, 53 💬
32 Gastric acid secretion 💬
1件: CHRM3 💬 Tolterodine 💬 Tolterodine 2件: 17, 53 💬
33 Gastric acid secretion 💬
1件: CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl 2件:  5 ,  6  💬
34 Gastric acid secretion 💬
1件: CHRM3 💬 Tropicamide 💬 Tropicamide 1件:  6  💬
35 Gastric acid secretion 💬
1件: HRH2 💬 Cimetidine 💬 Cimetidine 2件:  2 , 254 💬
36 Gastric acid secretion 💬
1件: HRH2 💬 Famotidine 💬 Famotidine 6件:  6 , 46, 61, 86, 98, 107 💬
37 Gastric acid secretion 💬
1件: HRH2 💬 Ranitidine 💬 Ranitidine 2件: 13, 65 💬
38 Gastric acid secretion 💬
1件: KCNQ1 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬
39 Gastric acid secretion 💬
1件: KCNQ1 💬 Ezogabine 💬 Ezogabine 2件:  2 , 144 💬
40 Gastric acid secretion 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
41 Gastric acid secretion 💬
1件: SSTR2 💬 Octreotide 💬 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227 💬
42 Gastric acid secretion 💬
1件: SSTR2 💬 Pasireotide 💬 Pasireotide 3件: 67, 74, 75 💬
43 Gastric acid secretion 💬
1件: SSTR2 💬 Somatostatin 💬 Somatostatin 2件: 67, 78 💬