Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Cocaine addiction 💬
1件: DDC 💬 Benserazide 💬 Benserazide 1件:  6  💬
2 Cocaine addiction 💬
1件: DDC 💬 Carbidopa 💬 Carbidopa 7件:  6 , 13, 17, 90, 140, 164, 201 💬
3 Cocaine addiction 💬
1件: DRD1 💬 Tavapadon 💬 Tavapadon 1件:  6  💬
4 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Apomorphine 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
5 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Dexpramipexole 💬 Dexpramipexole 1件:  2  💬
6 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Dopamine 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
7 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Flupentixol 💬 Flupentixol 1件: 97 💬
8 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Foslevodopa 💬 Foslevodopa 1件:  6  💬
9 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Levodopa 💬 Levodopa 6件:  6 , 17, 90, 140, 164, 201 💬
10 Cocaine addiction 💬
2件: DRD1, DRD2 💬 Pergolide 💬 Pergolide 1件:  6  💬
11 Cocaine addiction 💬
1件: DRD2 💬 Aripiprazole 💬 Aripiprazole 2件:  6 , 206 💬
12 Cocaine addiction 💬
1件: DRD2 💬 Bromocriptine 💬 Bromocriptine 2件:  6 , 74 💬
13 Cocaine addiction 💬
1件: DRD2 💬 Buspirone 💬 Buspirone 2件:  6 , 51 💬
14 Cocaine addiction 💬
1件: DRD2 💬 Cabergoline 💬 Cabergoline 3件:  6 , 74, 75 💬
15 Cocaine addiction 💬
1件: DRD2 💬 Cariprazine 💬 Cariprazine 1件: 21 💬
16 Cocaine addiction 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
17 Cocaine addiction 💬
1件: DRD2 💬 Domperidone 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
18 Cocaine addiction 💬
1件: DRD2 💬 Domperidone maleate 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
19 Cocaine addiction 💬
1件: DRD2 💬 Haloperidol 💬 Haloperidol 1件:  8  💬
20 Cocaine addiction 💬
1件: DRD2 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
21 Cocaine addiction 💬
1件: DRD2 💬 Lisuride 💬 Lisuride 2件:  6 , 86 💬
22 Cocaine addiction 💬
1件: DRD2 💬 Melperone 💬 Melperone 1件:  6  💬
23 Cocaine addiction 💬
1件: DRD2 💬 Metoclopramide 💬 Metoclopramide 2件: 46, 51 💬
24 Cocaine addiction 💬
1件: DRD2 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
25 Cocaine addiction 💬
1件: DRD2 💬 Pardoprunox 💬 Pardoprunox 1件:  6  💬
26 Cocaine addiction 💬
1件: DRD2 💬 Pimozide 💬 Pimozide 1件:  2  💬
27 Cocaine addiction 💬
1件: DRD2 💬 Piribedil 💬 Piribedil 1件:  6  💬
28 Cocaine addiction 💬
1件: DRD2 💬 Pramipexole 💬 Pramipexole 3件:  2 ,  6 , 20 💬
29 Cocaine addiction 💬
1件: DRD2 💬 Pridopidine 💬 Pridopidine 3件:  2 ,  6 ,  8  💬
30 Cocaine addiction 💬
1件: DRD2 💬 Quetiapine 💬 Quetiapine 2件:  6 , 13 💬
31 Cocaine addiction 💬
1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
32 Cocaine addiction 💬
1件: DRD2 💬 Ropinirole 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬
33 Cocaine addiction 💬
1件: DRD2 💬 Rotigotine 💬 Rotigotine 1件:  6  💬
34 Cocaine addiction 💬
1件: DRD2 💬 Sulpiride 💬 Sulpiride 2件:  6 , 70 💬
35 Cocaine addiction 💬
1件: DRD2 💬 Terguride 💬 Terguride 2件: 51, 86 💬
36 Cocaine addiction 💬
1件: DRD2 💬 Tiapride 💬 Tiapride 1件:  8  💬
37 Cocaine addiction 💬
1件: DRD2 💬 Trifluoperazine maleate 💬 Trifluoperazine 2件: 283, 284 💬
38 Cocaine addiction 💬
1件: DRD2 💬 Trifluoperazine 💬 Trifluoperazine 2件: 283, 284 💬
39 Cocaine addiction 💬
1件: GRIA2 💬 Perampanel 💬 Perampanel 3件:  2 ,  6 , 144 💬
40 Cocaine addiction 💬
1件: GRIA2 💬 Talampanel 💬 Talampanel 2件:  2 ,  6  💬
41 Cocaine addiction 💬
1件: GRIA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
42 Cocaine addiction 💬
6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
43 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate 2件:  6 , 206 💬
44 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
45 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
46 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine 3件:  2 ,  4 , 70 💬
47 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
48 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬
49 Cocaine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
50 Cocaine addiction 💬
1件: MAOA 💬 Moclobemide 💬 Moclobemide 1件:  6  💬
51 Cocaine addiction 💬
2件: MAOA, MAOB 💬 Iproniazid 💬 Iproniazid 1件:  6  💬
52 Cocaine addiction 💬
2件: MAOA, MAOB 💬 Phenelzine 💬 Phenelzine 1件:  6  💬
53 Cocaine addiction 💬
3件: MAOA, MAOB, SLC6A3 💬 Phentermine 💬 Phentermine 1件: 97 💬
54 Cocaine addiction 💬
1件: MAOB 💬 Rasagiline 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬
55 Cocaine addiction 💬
1件: MAOB 💬 Rasagiline tartrate 💬 Rasagiline 6件:  2 ,  5 ,  6 , 17, 58, 66 💬
56 Cocaine addiction 💬
1件: MAOB 💬 Safinamide 💬 Safinamide 2件:  6 , 17 💬
57 Cocaine addiction 💬
1件: MAOB 💬 Selegiline 💬 Selegiline 1件:  6  💬
58 Cocaine addiction 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
59 Cocaine addiction 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
60 Cocaine addiction 💬
1件: SLC18A2 💬 Deutetrabenazine 💬 Deutetrabenazine 1件:  8  💬
61 Cocaine addiction 💬
1件: SLC18A2 💬 Tetrabenazine 💬 Tetrabenazine 1件:  8  💬
62 Cocaine addiction 💬
1件: SLC18A2 💬 Valbenazine 💬 Valbenazine 1件:  8  💬
63 Cocaine addiction 💬
1件: SLC6A3 💬 Armodafinil 💬 Armodafinil 3件:  6 , 13, 84 💬
64 Cocaine addiction 💬
1件: SLC6A3 💬 Bupropion 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
65 Cocaine addiction 💬
1件: SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬
66 Cocaine addiction 💬
1件: SLC6A3 💬 Methylphenidate 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬