Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ACTIMMUNE[1] Interferon gamma-1b[1] Interferon gamma-1b 💬[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[1] 326 💬
2Actimmune Registry[1] Interferon gamma-1b[1] Interferon gamma-1b 💬[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[1] 326 💬
3AP1903----[3] 60, 285, 326 💬
4AP1903 A594----[3] 60, 285, 326 💬
5BPX-501----[3] 60, 285, 326 💬
6BPX-501 cells----[3] 60, 285, 326 💬
7BPX-501 T cells----[4] 65, 284, 285, 326 💬
8Busulfan[1] Busulfan[1] Busulfan 💬--[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
9Busulfan, Cyclophosphamide, Thymoglobulin, Fludarabine (Conditioning regimen)[4] Antithymocyte immunoglobulin (rabbit),
Busulfan,
Cyclophosphamide,
Fludarabine		[4] Busulfan ,
Cyclophosphamide ,
Cyclophosphamide ,
Fludarabine 💬		[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[1] 326 💬
10Calcitriol[1] Calcitriol[1] Calcitriol 💬[1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
11CALD HR-D (High-Risk, Regimen C)----[5] 19, 20, 125, 234, 326 💬
12CALD HR-D (High-Risk, Regimen D)----[5] 19, 20, 125, 234, 326 💬
13CALD SR-A (Standard-Risk, Regimen A)----[5] 19, 20, 125, 234, 326 💬
14CALD SR-B (Standard-Risk, Regimen B)----[5] 19, 20, 125, 234, 326 💬
15Campath[1] Alemtuzumab[1] Alemtuzumab 💬[1] CD52 💬-[12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326 💬
16Campath, Busulfan, Clofarabine[2] Busulfan,
Clofarabine		[2] Busulfan ,
Clofarabine 💬		[3] POLA1,
POLA2,
RRM1 💬		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[1] 326 💬
17Campath-1H[1] Alemtuzumab[1] Alemtuzumab 💬[1] CD52 💬-[6] 19, 20, 60, 234, 285, 326 💬
18CD34+ enriched, T Cell Depleted donor stem cell product----[1] 326 💬
19Clofarabine[1] Clofarabine[1] Clofarabine 💬[3] POLA1,
POLA2,
RRM1 💬		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 234, 326 💬
20Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
21Cyclophosphamide 30[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[3] 65, 285, 326 💬
22Cyclophosphamide 40[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[3] 65, 285, 326 💬
23Cyclosporin[1] Cyclosporine[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326 💬
24Cyclosporin, Methotrexate (GVHD prophylaxis)[2] Cyclosporine,
Methotrexate		[2] Methotrexate ,
Cyclosporine 💬		[7] DHFR,
DHFR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[38] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, Axon guidance, B cell receptor signaling pathway, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Folate biosynthesis, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, One carbon pool by folate, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 326 💬
25Fludarabine[1] Fludarabine[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[19] 11, 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
26Fludarabine monophosphate[1] Fludarabine[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 65, 284, 326 💬
27Hematopoetic Stem Cell Transplantation----[5] 19, 65, 120, 160, 326 💬
28IMD----[5] 19, 20, 125, 234, 326 💬
29IMD Preparative Regimen----[5] 19, 20, 125, 234, 326 💬
30Interferon Gamma[1] Interferon Gamma---[8] 18, 65, 85, 107, 228, 299, 301, 326 💬
31INTERFERON GAMMA-1B[2] Interferon Gamma,
Interferon gamma-1b		[1] Interferon gamma-1b 💬[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
32Methotrexate[1] Methotrexate[1] Methotrexate 💬[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
33Osteopetrosis Haploidentical Only Preparative Regimen----[5] 19, 20, 125, 234, 326 💬
34Osteopetrosis Only Preparative Regimen----[5] 19, 20, 125, 234, 326 💬
35RhPTH[1] Parathyroid hormone[1] Parathyroid hormone 💬[2] PTH1R,
PTH2R 💬		[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[3] 70, 235, 326 💬
36Rimiducid[1] Rimiducid[1] Rimiducid 💬[1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326 💬
37Rivogenlecleucel----[4] 19, 60, 285, 326 💬
38Rivogenleucleucel----[3] 60, 285, 326 💬
39Stem Cell Transplantation----[10] 13, 19, 20, 46, 65, 90, 125, 164, 234, 326 💬
40Systemic chemotherapy and antibodies----[2] 62, 326 💬
41Thymoglobulin[1] Antithymocyte immunoglobulin (rabbit)---[7] 36, 51, 60, 65, 96, 285, 326 💬