Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Azathioprine [3] Azathioprine; Azatioprina; Imuran[1] Azathioprine 💬--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
2 Benralizumab [2] Benralizumab; Fasenra[1] Benralizumab 💬[1] IL5RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299 💬
3 Coenzyme M [2] MESNA; UROMITEXAN---[10] 11, 13, 44, 45, 51, 60, 65, 85, 96, 164 💬
4 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
5 Cyclosporine [10] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
6 Filgrastim [7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
7 Human immunoglobulin G [19] Bivigam; CUTAQUIG; CUVITRU; GAMMAGARD LIQUID; Gammaplex; GAMUNEX-C; Hizentra; Human immunoglobulin G; HUMAN NORMAL IMMUNOGLOBULIN; HYQVIA; Immune globulin; Immunoglobulin; IMMUNOGLOBULIN G; IVIg; KIOVIG; Octagam; PANZYGA; Privigen; Vivaglobin---[10] 11, 13, 14, 17, 43, 45, 50, 51, 63, 65 💬
8 Hydroxychloroquine [3] HYDROXYCHLOROQUINE; HYDROXYCHLOROQUINE SULFATE; PLAQUENIL[1] Hydroxychloroquine 💬--[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
9 Infliximab [6] Flixabi; Inflectra; Infliximab; Remicade; REMSIMA; Zessly[1] Infliximab 💬[1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
10 Mepolizumab [2] Mepolizumab; NUCALA[1] Mepolizumab 💬[1] IL5 💬[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[4] 44, 45, 98, 162 💬
11 Methotrexate [6] Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; METOJECT; METOTREXATO; Méthotrexate[1] Methotrexate 💬[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
12 Methylprednisolone [4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
13 Mycophenolate mofetil [3] CELLCEPT; Mycophenolate mofetil; Mycophenolate mofetil TEVA[1] Mycophenolate mofetil 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
14 Mycophenolic acid [5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[1] Mycophenolic acid 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
15 Naltrexone [2] Naltrexone; Naltrexone Hydrochloride[1] Naltrexone 💬[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
16 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
17 Prednisone [3] Prednisona; Prednisone; RAYOS[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
18 Rituximab [6] MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; Truxima[1] Rituximab 💬[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬