Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Arachidonic acid metabolism 💬
[3] PTGES, PTGS1, PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
2 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
4 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
5 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
6 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
7 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
8 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
9 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
10 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
11 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
12 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
13 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
14 Arachidonic acid metabolism 💬
[2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
15 Metabolic pathways 💬
[3] PTGES, PTGS1, PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
16 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
17 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
18 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
19 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
20 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
21 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
22 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
23 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
24 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
25 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
26 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
27 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
28 Metabolic pathways 💬
[2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
29 Platelet activation 💬
[1] PTGS1 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
30 Platelet activation 💬
[1] PTGS1 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
31 Platelet activation 💬
[1] PTGS1 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
32 Platelet activation 💬
[1] PTGS1 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
33 Platelet activation 💬
[1] PTGS1 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
34 Platelet activation 💬
[1] PTGS1 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
35 Platelet activation 💬
[1] PTGS1 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
36 Platelet activation 💬
[1] PTGS1 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
37 Platelet activation 💬
[1] PTGS1 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
38 Platelet activation 💬
[1] PTGS1 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
39 Platelet activation 💬
[1] PTGS1 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
40 Platelet activation 💬
[1] PTGS1 💬 Salsalate 💬 Salsalate [1]  5  💬
41 Platelet activation 💬
[1] PTGS1 💬 Sulindac 💬 Sulindac [1] 206 💬
42 Platelet activation 💬
[1] PTGS1 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
43 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
44 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
45 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
46 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
47 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
48 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
49 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
50 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
51 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
52 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
53 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
54 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
55 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
56 Regulation of lipolysis in adipocytes 💬
[2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
57 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
58 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
59 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
60 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
61 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
62 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
63 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
64 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
65 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
66 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
67 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
68 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
69 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
70 Serotonergic synapse 💬
[2] PTGS1, PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬