Dehydroepiandrosterone ( DrugBank: Dehydroepiandrosterone )


5 diseases
告示番号疾患名(ページ内リンク)臨床試験数
49全身性エリテマトーデス5
53シェーグレン症候群3
83アジソン病1
96クローン病1
113筋ジストロフィー1

49. 全身性エリテマトーデス


臨床試験数 : 946 薬物数 : 722 - (DrugBank : 186) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 198
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00189124
(ClinicalTrials.gov)
September 200313/9/2005Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) PreventionDoes DHEA Improve Endothelial Dysfunction and Other Cardiovascular Risk Factors in Premenopausal Women With Systemic Lupus?Systemic Lupus ErythematosusDrug: Dehydroepiandrosterone (DHEA)University of MichiganArthritis FoundationCompleted18 YearsN/AFemale13Phase 2/Phase 3United States
2NCT00391924
(ClinicalTrials.gov)
May 200024/10/2006Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's SyndromeFatigue and General Well-Being in Patients With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome: Effects of Dehydroepiandrosterone AdministrationLupus Erythematosus, Systemic;Sjogren's SyndromeDrug: DehydroepiandrosteroneUMC UtrechtUniversity Medical Centre Groningen;Dutch Arthritis AssociationCompleted18 YearsN/AFemale120Phase 2Netherlands
3NCT00004662
(ClinicalTrials.gov)
March 199624/2/2000Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Active Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)Northwestern UniversityCompleted18 YearsN/AFemale300Phase 3NULL
4NCT00004665
(ClinicalTrials.gov)
June 199524/2/2000Phase II Study of Long-Term Dehydroepiandrosterone for Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)Northwestern UniversityCompleted18 YearsN/AFemale20Phase 2NULL
5NCT00004795
(ClinicalTrials.gov)
August 199424/2/2000Phase II/III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Mild to Moderate Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)Northwestern UniversityCompleted18 YearsN/AFemale190Phase 2/Phase 3NULL

53. シェーグレン症候群


臨床試験数 : 283 薬物数 : 320 - (DrugBank : 101) / 標的遺伝子数 : 55 - 標的パスウェイ数 : 180
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00543166
(ClinicalTrials.gov)
February 20039/10/2007Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on FatigueSex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on FatigueSjogren's SyndromeDrug: dehydroepiandrosteroneHelsinki UniversityGöteborg University;Uppsala UniversityActive, not recruiting18 Years80 YearsBoth107Phase 4Finland
2NCT00391924
(ClinicalTrials.gov)
May 200024/10/2006Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's SyndromeFatigue and General Well-Being in Patients With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome: Effects of Dehydroepiandrosterone AdministrationLupus Erythematosus, Systemic;Sjogren's SyndromeDrug: DehydroepiandrosteroneUMC UtrechtUniversity Medical Centre Groningen;Dutch Arthritis AssociationCompleted18 YearsN/AFemale120Phase 2Netherlands
3NCT00001598
(ClinicalTrials.gov)
May 19973/11/1999DHEA Treatment for Sjogren's SyndromeDehydroepiandrosterone (DHEA) Treatment for Sjogren's SyndromeLacrimal Apparatus Disease;Salivary Gland Disease;Sjogren's Syndrome;XerostomiaDrug: DehydroepiandrosteroneNational Institute of Dental and Craniofacial Research (NIDCR)NULLCompletedN/AN/AFemale28Phase 2United States

83. アジソン病


臨床試験数 : 20 薬物数 : 43 - (DrugBank : 13) / 標的遺伝子数 : 6 - 標的パスウェイ数 : 18
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00004313
(ClinicalTrials.gov)
August 199518/10/1999Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone Replacement for Primary Adrenal InsufficiencyAddison's DiseaseDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)University of California, Los AngelesCompleted18 YearsN/ABoth40Phase 3NULL

96. クローン病


臨床試験数 : 2,400 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 168 - 標的パスウェイ数 : 214
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00106314
(ClinicalTrials.gov)
January 200522/3/2005An Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Crohn's DiseaseA Randomized, Double-Blind, Multi-Center, Dose Response, Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Moderately Active Crohn's DiseaseCrohn's DiseaseDrug: Dehydroepiandrosterone [DHEA]Inflabloc PharmaceuticalsNULLCompleted18 YearsN/ABoth75Phase 2United States;Canada

113. 筋ジストロフィー


臨床試験数 : 622 薬物数 : 485 - (DrugBank : 99) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 168
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00167609
(ClinicalTrials.gov)
November 200410/9/2005Efficacy and Safety of DHEA for Myotonic DystrophyPhase 3 Study of Oral Dehydroepiandrosterone (DHEA) in Adults With Myotonic DystrophyMyotonic DystrophyDrug: dehydroepiandrosterone 100 and 400 mgUniversity of VersaillesAssociation Française contre les Myopathies (AFM), Paris;AP-HPCompleted18 Years70 YearsBoth75Phase 2/Phase 3France