Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
BRAF 4件: BRAF, FLT3, KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
2 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
3 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
KIT 1件: KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
4 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
5 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
6 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
7 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
10 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
11 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
12 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
13 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
14 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
15 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
16 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
SCN5A 1件: SCN5A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
17 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
SCN5A 1件: SCN5A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
18 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
19 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
20 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
21 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
22 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
23 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 2件: 6 , 86 💬 |
24 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
25 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
26 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
27 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
28 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
29 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
NR3C2 1件: NR3C2 💬 |
D00443 D00443 💬 |
Spironolactone | 046 8件: 46, 58, 67, 86, 113, 210, 218, 225 💬 |
30 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
31 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
32 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
33 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
34 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
35 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
36 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
37 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
38 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
39 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
40 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
41 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
42 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
43 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
44 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
45 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
46 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
47 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
48 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
49 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
50 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
51 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
52 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
53 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
PARP1 2件: PARP1, PARP2 💬 |
D09730 D09730 💬 |
Olaparib | 086 2件: 86, 285 💬 |
54 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
55 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
56 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
57 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
58 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
59 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
60 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
61 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
62 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 41 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
63 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
64 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
65 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
66 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
67 | Base excision repair 💬 Related to 2 target genes, 1 drug (DrugBank) and 2 diseases in DDrare |
PARP1 2件: PARP1, PARP2 💬 |
D09730 D09730 💬 |
Olaparib | 086 2件: 86, 285 💬 |
68 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
69 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
70 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 |
71 | Bladder cancer 💬 Related to 10 target genes, 23 drugs (DrugBank) and 22 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
72 | Bladder cancer 💬 Related to 10 target genes, 23 drugs (DrugBank) and 22 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
73 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
BRAF 4件: BRAF, FLT4, KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
74 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
75 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
76 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
77 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
78 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
79 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
80 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
81 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
82 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
83 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
84 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
85 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
86 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
87 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
88 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
89 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AVPR1A 1件: AVPR1A 💬 |
D07748 D07748 💬 |
Conivaptan | 086 1件: 86 💬 |
90 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
91 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
92 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
93 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 1件: 86 💬 |
94 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
95 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
96 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
97 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
98 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
FLT4 4件: FLT4, KDR, PDGFRB, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
99 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 8件: 11, 13, 49, 51, 70, 86, 222, 256 💬 |
100 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 6件: 6 , 46, 61, 86, 98, 107 💬 |
101 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
102 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
103 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
104 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
105 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 2件: ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
106 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
107 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
108 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
109 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
110 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 2件: 6 , 86 💬 |
111 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
112 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
113 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
114 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
115 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
116 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 1件: 86 💬 |
117 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
118 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
119 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
TAS1R2 2件: TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 4件: 6 , 13, 67, 86 💬 |
120 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
121 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
122 | Cell cycle 💬 Related to 10 target genes, 9 drugs (DrugBank) and 21 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
123 | Cell cycle 💬 Related to 10 target genes, 9 drugs (DrugBank) and 21 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
124 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
125 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1D 1件: CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
126 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
127 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
128 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
129 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
FLT3 5件: FLT3, KIT, PDGFRB, RAF1, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
130 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
131 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
KIT 3件: KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
132 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
133 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
134 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
135 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
136 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
137 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
138 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
139 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
140 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
141 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
142 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 1件: 86 💬 |
143 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
144 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
145 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
146 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
147 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
148 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 |
149 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 2件: 86, 210 💬 |
150 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 3件: 13, 86, 299 💬 |
151 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
152 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
153 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
154 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
155 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
156 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
157 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
158 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
159 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
KEAP1 1件: KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬 |
160 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
161 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 |
162 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
163 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
164 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 2件: ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
165 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB2 1件: ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 12件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
166 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
AR 3件: AR, ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
167 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
168 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
169 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
170 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
171 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
172 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
173 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
174 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
175 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
176 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
177 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
178 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
PDGFRB 2件: PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
179 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
180 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
181 | Chronic myeloid leukemia 💬 Related to 17 target genes, 20 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
182 | Chronic myeloid leukemia 💬 Related to 17 target genes, 20 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
183 | Chronic myeloid leukemia 💬 Related to 17 target genes, 20 drugs (DrugBank) and 29 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
184 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
185 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
186 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
187 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 25 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
188 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 2件: 6 , 86 💬 |
189 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
190 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
191 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
192 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
193 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
194 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
195 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
196 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
197 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
198 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
199 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 3件: 11, 13, 86 💬 |
200 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
201 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
202 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
203 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
204 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
205 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
206 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
207 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
208 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
209 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
210 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
211 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
ACVR2A 1件: ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 2件: 86, 284 💬 |
212 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
213 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 3件: 11, 13, 86 💬 |
214 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
215 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
PRL 1件: PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
216 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
217 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
218 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
219 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
220 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
PARP1 1件: PARP1 💬 |
D09730 D09730 💬 |
Olaparib | 086 2件: 86, 285 💬 |
221 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
PDK2 3件: PDK2, PDK3, PDK4 💬 |
D05857 D05857 💬 |
Sodium dichloroacetate | 086 1件: 86 💬 |
222 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
223 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
224 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
225 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
226 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
227 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
228 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
229 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
230 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 3件: DRD2, DRD3, DRD4 💬 |
D08132 D08132 💬 |
Lisuride | 006 2件: 6 , 86 💬 |
231 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SCN1A 1件: SCN1A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
232 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SCN1A 1件: SCN1A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
233 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
234 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
BRAF 4件: BRAF, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
235 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
236 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 3件: 11, 13, 86 💬 |
237 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
238 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
239 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
240 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
241 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
242 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
243 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
244 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
245 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
246 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
247 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
248 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
249 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
250 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
251 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
252 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
253 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
254 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
255 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
256 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
257 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
258 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
259 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
260 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
261 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
262 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 1件: OPRM1 💬 |
D08233 D08233 💬 |
Morphine | 036 5件: 36, 46, 70, 85, 86 💬 |
263 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
264 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
265 | Fc gamma R-mediated phagocytosis 💬 Related to 9 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
266 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
ACVR2A 1件: ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 2件: 86, 284 💬 |
267 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
268 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
KDR 1件: KDR 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
269 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
KEAP1 1件: KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬 |
270 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
271 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 |
272 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
273 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
274 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
275 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
276 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
277 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
278 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
279 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
280 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
281 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
282 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 4件: 58, 67, 86, 113 💬 |
283 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D00255 D00255 💬 |
Carvedilol | 057 4件: 57, 86, 113, 210 💬 |
284 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
285 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 2件: 6 , 86 💬 |
286 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
287 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
288 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
289 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
290 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
291 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRB 2件: PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
292 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
293 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
294 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 6件: 6 , 46, 61, 86, 98, 107 💬 |
295 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
296 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
297 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
298 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
BRAF 3件: BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
299 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
300 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
301 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
302 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
303 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
304 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
305 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
306 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
ANPEP 1件: ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 1件: 86 💬 |
307 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
308 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
309 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
310 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
311 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
312 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
313 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
314 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
315 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
316 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
317 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
318 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
319 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
320 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
321 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
ANPEP 1件: ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 1件: 86 💬 |
322 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
FLT3 2件: FLT3, KIT 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
323 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
324 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 3件: 11, 13, 86 💬 |
325 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
326 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
327 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
KIT 1件: KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
328 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, |