Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Albendazole [2] Albendazole; Eskazole[1] D00134 --[12] 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
2 Apomorphine [4] APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride[1] D07460 [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7
3 Botulinum toxin type A [8] Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] D00783 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
4 Creatine [1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
5 Davunetide [1] Davunetide[1] D09401 --[3] 5, 7, 127
6 Donepezil [3] ARICEPT; Donepezil; Donepezil Hydrochloride[1] D07869 [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
7 Droxidopa [4] DOPS; Droxidopa; L-DOPS; Northera[1] D01277 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170
8 Emeramide [1] Emeramide---[2] 5, 17
9 Fasudil [1] Fasudil[1] D07941 [2] ROCK1,
ROCK2 💬		[23] Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 2, 5, 7, 51
10 Flortaucipir [1] Flortaucipir[1] D11210 [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127
11 Fludeoxyglucose (18F) [2] 18F-FDG; Fludeoxyglucose---[8] 5, 6, 7, 13, 84, 85, 127, 300
12 Flutemetamol [1] Flutemetamol---[4] 5, 6, 7, 127
13 Flutemetamol (18F) [2] Flutemetamol; Vizamyl---[3] 5, 7, 127
14 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
15 Gosuranemab [1] BMS-986168[1] D11293 [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 5
16 Hydrogen [2] Dihydrogen; Hydrogen---[7] 5, 6, 17, 65, 83, 97, 226
17 Hydroxide ion [2] Example; Hydroxide---[6] 5, 11, 46, 96, 97, 284
18 Ioflupane I-123 [3] DaTSCAN; Ioflupane; Ioflupane I 123---[3] 2, 5, 6
19 Levocarnitine [4] Carnitine; L-Carnitine; Levocarnitine; Xyzal[1] D02176 --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
20 Linoleic acid [1] Linoleic acid---[8] 2, 5, 6, 13, 76, 78, 256, 299
21 Lipoic acid [3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid---[5] 2, 5, 13, 14, 20
22 Lithium citrate [2] Lithium; LITHIUM CITRATE[1] D04749 --[5] 2, 5, 6, 7, 8
23 Masitinib [1] Masitinib[1] D10229 [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96
24 Nicotinamide [3] Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
25 Nitrogen [1] Nitrogen[1] D00083 --[5] 5, 6, 17, 211, 299
26 Raclopride [1] Raclopride---[4] 5, 6, 7, 17
27 Rasagiline [4] AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate[2] D08469 ,
D10829 		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[6] 2, 5, 6, 17, 58, 66
28 Riluzole [2] Rilutek; Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
29 Rivastigmine [3] Exelon; Rivastigmine; Rivastigmine Transdermal System[1] D03822 [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
30 Salsalate [1] Salsalate[1] D00428 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
31 Suvorexant [1] Suvorexant[1] D10082 [2] HCRTR1,
HCRTR2 💬		[1] Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13
32 Tideglusib [1] Tideglusib---[2] 5, 113
33 Tolfenamic acid [1] Tolfenamic Acid[1] D01183 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
34 TPI-287 [1] TPI-287---[2] 5, 7
35 Trihexyphenidyl [1] Trihexyphenidyl[1] D08638 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6
36 Ubidecarenone [3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
37 Valproic acid [3] Valproate; VALPROATE SODIUM; Valproic acid[1] D00399 [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
38 Water [8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] D00001 --[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
39 Zoledronic acid [4] ACLASTA; Zoledronate; Zoledronic acid; Zometa[2] D01968 ,
D08689 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
40 Zolpidem [2] Zolpidem; Zolpidem Tartrate[1] D08690 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46