Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Pabinafusp alfa [1] Pabinafusp alfa[1] D11812 [2] IDS,
TFRC 💬		[8] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬[1] 19
2 Paclitaxel [1] Paclitaxel[1] D00491 [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[2] 46, 85
3 Padsevonil [1] Padsevonil[1] D11842 [3] SV2A,
SV2B,
SV2C 💬		[1] ECM-receptor interaction 💬[1] 149
4 Palifermin [2] Kepivance; Palifermin[1] D05338 [1] FGFR2 💬[13] Calcium signaling pathway, Central carbon metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Gastric cancer, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells 💬[5] 13, 36, 38, 39, 65
5 Palmidrol [1] Palmitoylethanolamide[1] D08328 --[1] 2
6 Palmitic Acid [1] Palmitate[1] D05341 --[1] 63
7 Palmitoleic Acid [1] Palmitoleic Acid---[1] 97
8 Palovarotene [1] PALOVAROTENE[1] D09365 [1] RARG 💬-[1] 272
9 Pamidronic acid [1] Pamidronate[1] D07281 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 270, 271, 274
10 Pamrevlumab [1] PAMREVLUMAB[1] D10969 [1] CCN2 💬[2] Apelin signaling pathway, Hippo signaling pathway 💬[2] 85, 113
11 Panax notoginseng root [1] Sanqi[1] D10765 --[1] 222
12 Panax quinquefolius whole [2] American Ginseng; Panax Quinquefolius---[2] 13, 46
13 Pancrelipase [2] Pancreatin; Pancrelipase[1] D05349 --[2] 298, 299
14 Pancrelipase amylase [8] CREON; PANCREAZE; Pancrelipase; PANCRELIPASE AMYLASE; PERTZYE; Ultrase; ULTRESA; ZENPEP---[1] 299
15 Pantethine [1] Pantethine[1] D01234 --[1] 120
16 Pantoprazole [1] Pantoprazole[1] D05353 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65
17 Paquinimod [1] Paquinimod---[2] 49, 51
18 Parathyroid hormone [5] Natpar; Natpara; Parathyroid hormone; PREOTACT; RhPTH[1] D05364 [2] PTH1R,
PTH2R 💬		[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[4] 65, 70, 235, 326
19 Pardoprunox [1] Pardoprunox[1] D09397 [3] DRD2,
DRD3,
HTR1A 💬		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6
20 Parecoxib [1] Parecoxib[1] D03716 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271
21 Paricalcitol [1] Paricalcitol[1] D00930 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298
22 Parnaparin [2] Parnaparin; PARNAPARIN SODIUM[1] D07510 [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[1] 97
23 Paroxetine [1] Paroxetine[1] D02362 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85
24 Parsaclisib [2] INCB050465; Parsaclisib[1] D11437 [1] PIK3CD 💬[106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[3] 35, 53, 61
25 Pasireotide [3] Pasireotida; Pasireotide; SIGNIFOR[1] D10147 [4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬		[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 67, 74, 75
26 Pateclizumab [1] MLTA3698A[1] D10187 [1] LTA 💬[7] Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, NF-kappa B signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
27 Pazopanib [1] Pazopanib---[1] 227
28 PCO-371 [0] ---[1] 235
29 PD-0299685 [1] PD-0299685---[1] 226
30 Pectin [1] Pectin[1] D02316 --[1] 96
31 Peficitinib [1] Peficitinib[1] D10653 [3] JAK1,
JAK2,
JAK3 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
32 Pegademase [1] Adagen[1] D05384 --[1] 65
33 Pegcetacoplan [2] Aspaveli; PEGCETACOPLAN[1] D11613 [1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[4] 2, 61, 62, 222
34 Pegfilgrastim [1] Pegfilgrastim[1] D06889 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 60
35 Peginesatide [2] Hematide; Peginesatide[1] D09946 [1] EPOR 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 283
36 Peginterferon beta-1a [2] PEGINTERFERON BETA-1A; Plegridy[1] D10483 [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13
37 Pegsunercept [2] Pegsunercept; STNF-R1[1] D05393 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
38 Pegunigalsidase alfa [1] PEGUNIGALSIDASE ALFA[1] D11685 --[1] 19
39 Pegvaliase [4] Palynziq; PEGVALIASE; Pegvaliase-Pqpz; RAvPAL-PEG[1] D11077 [1] PAH 💬[5] Biosynthesis of amino acids, Folate biosynthesis, Metabolic pathways, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis 💬[1] 240
40 Pegvisomant [1] Pegvisomant[1] D05394 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 265
41 Pelubiprofen [1] Pelubiprofen[1] D01865 --[1] 46
42 Pemafibrate [1] Pemafibrate[1] D10711 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[1] 93
43 Pembrolizumab [1] Pembrolizumab[1] D10574 [1] PDCD1 💬[3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[2] 25, 285
44 Pemirolast [1] PEMIROLAST[1] D07476 --[1] 113
45 Penciclovir [0] [1] D05407 --[1] 13
46 Penicillamine [2] D-penicillamine; Penicillamine[1] D00496 --[2] 51, 171
47 Pentamidine [2] Pentamidina; Pentamidine[1] D08333 --[2] 61, 65
48 Pentetic acid [1] DTPA[1] D05422 --[2] 28, 299
49 Pentetreotide [1] Pentetreotide[1] D01859 --[1] 75
50 Pentosan polysulfate [1] Pentosan polysulfate---[3] 19, 26, 226
51 Pentoxifylline [1] Pentoxifylline[1] D00501 --[12] 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298
52 Perampanel [2] Fycompa; Perampanel[1] D08964 [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144
53 Perflubutane [1] Perflubutane[1] D05440 --[2] 298, 300
54 Perflutren [1] Optison[1] D01738 --[1] 96
55 Pergolide [1] PERGOLIDE[1] D08339 [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
56 Perhexiline [1] Perhexiline[1] D08340 [8] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CPT1A,
CPT1B,
CPT1C,
CPT2 💬		[47] AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 58, 272
57 Perindopril [2] Coversyl; Perindopril[1] D03753 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 58, 113, 167, 222
58 Pertussis vaccine [1] Pertussis vaccine[1] D06514 --[2] 13, 46
59 Petrolatum [1] Petrolatum[1] D05331 --[1] 158
60 Pexidartinib [1] Turalio[1] D11270 [3] CSF1R,
FLT3,
KIT 💬		[15] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[1] 34
61 PF-00489791 [1] PF-00489791---[1] 86
62 PF-06650833 [1] PF-06650833---[1] 46
63 PF-06651600 [1] PF-06651600---[3] 46, 96, 97
64 PF-06700841 [1] PF-06700841---[3] 49, 96, 97
65 PH-797804 [1] PH-797804---[1] 46
66 Phenelzine [1] Nardil[1] D08349 [2] MAOA,
MAOB 💬		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6
67 Phenindione [0] [1] D08354 [1] VKORC1 💬[3] Biosynthesis of cofactors, Metabolic pathways, Ubiquinone and other terpenoid-quinone biosynthesis 💬[1] 65
68 Phenothiazine [1] Phenothiazine[1] D02601 --[1] 127
69 Phenoxymethylpenicillin [0] [1] D05411 --[1] 97
70 Phentermine [1] Phentermine[1] D05458 [5] MAOA,
MAOB,
SLC6A2,
SLC6A3,
SLC6A4 💬		[16] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Phenylalanine metabolism, Serotonergic synapse, Synaptic vesicle cycle, Tryptophan metabolism, Tyrosine metabolism 💬[1] 97
71 Phenylalanine [1] Phenylalanine[1] D00021 --[2] 75, 240
72 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
73 Phenylephrine [1] Phenylephrine[1] D08365 [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
74 Phenytoin [1] Phenytoin[1] D00512 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13
75 Phosphate ion [1] Phosphate---[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
76 Phosphatidyl serine [0] ---[2] 90, 97
77 Phosphorus [1] Phosphorus---[1] 238
78 Phosphorus P-32 [0] ---[1] 37
79 Phylloquinone [4] Phylloquinone; Phytomenadione; Vitamin K; Vitamin K1---[4] 46, 96, 288, 299
80 PI-0824 [1] PI-0824---[1] 35
81 Piclidenoson [1] Piclidenoson[1] D10971 [1] ADORA3 💬[3] Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
82 Piclozotan [1] Piclozotan---[1] 6
83 Picosulfuric acid [1] Picosulfate---[3] 97, 98, 291
84 Pidolic acid [0] ---[1] 70
85 Pilocarpine [2] Pilocarpine; Pilocarpine Hydrochloride[1] D00525 [2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299
86 Pimavanserin [1] Pimavanserin---[1] 6
87 Pimecrolimus [1] Pimecrolimus[1] D05480 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 160
88 Pimozide [1] Pimozide[1] D00560 [2] ADRA2A,
DRD2 💬		[9] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2
89 Pioglitazone [1] Pioglitazone[1] D08378 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
90 Piperacillin [1] PIPERACILLIN[2] D02251 ,
D08380 		--[1] 299
91 Piperazine [1] Piperazine[1] D00807 --[2] 58, 272
92 Pirfenidone [2] Esbriet; Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
93 Piribedil [1] Piribedil[1] D07305 [2] DRD2,
DRD3 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
94 Pitavastatin [1] Pitavastatin---[1] 49
95 Pitolisant [1] Pitolisant[1] D10749 [1] HRH3 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193
96 Pittsburgh Compound B [2] C-11 PiB; Pittsburgh Compound B---[1] 127
97 Pixantrone [1] Pixantrone[1] D05522 [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[2] 11, 13
98 Placental Mesenchymal Stem Cells [2] Placental Mesenchymal Stem Cells; PLX-PAD---[2] 86, 118
99 Plantago seed [2] Psyllium; Psyllium husk[1] D05525 --[3] 6, 28, 97
100 Plasma protein fraction (human) [1] Octaplas---[1] 64
101 Pleconaril [1] PLECONARIL[1] D05528 --[1] 2
102 Plerixafor [2] Mozobil; PLERIXAFOR[1] D08971 [1] CXCR4 💬[14] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[5] 19, 20, 65, 285, 299
103 PLN-74809 [1] PLN-74809---[2] 85, 94
104 Polaprezinc [1] Polaprezinc[1] D01611 --[2] 96, 97
105 Polidocanol [1] Polidocanol[1] D01993 --[1] 279
106 Polyethylene glycol [4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350[1] D03370 --[17] 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337
107 Pomalidomide [3] Imnovid; Pomalidomida; Pomalidomide[1] D08976 [2] IL6,
TNF 💬		[80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[5] 28, 51, 85, 227, 331
108 Ponesimod [2] PONESIMOD; Ponvory[1] D11215 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 13
109 Poractant alfa [1] Curosurf[1] D08402 --[1] 211
110 Porphobilinogen [1] Porphobilinogen---[1] 254
111 Posaconazole [2] Noxafil; POSACONAZOLE[1] D02555 --[3] 60, 65, 299
112 Posiphen [1] Posiphen---[1] 6
113 Potassium [1] Potassium[1] D08403 --[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235
114 Potassium carbonate [0] [1] D02038 --[3] 6, 96, 291
115 Pozelimab [1] Pozelimab[1] D11477 [1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 11, 62
116 Pramipexole [7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[1] D05575 [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
117 Prasinezumab [1] Prasinezumab[1] D11420 [1] SNCA 💬[3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 6
118 Prasterone [3] Dehydroepiandrosterone; DHEA; Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 49, 53, 83, 86, 96, 113
119 Pravastatin [2] Pravastatin; Pravastatin sodium[1] D08410 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
120 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] D00472 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
121 Prednisolone acetate [1] PREDNISOLONE ACETATE[1] D00980 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 222
122 Prednisone [3] Prednisona; Prednisone; RAYOS[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
123 Prednisone acetate [2] Cortancyl; Prednisone acetate[1] D08416 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[6] 35, 41, 46, 49, 162, 224
124 Pregabalin [2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
125 Preimplantation factor [2] Preimplantation factor; Synthetic PreImplantation Factor---[1] 95
126 Preladenant [1] Preladenant[1] D09717 [1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
127 Pridopidine [1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8
128 Primidone [1] Primidone[1] D00474 --[1] 2
129 PRM-151 [1] PRM-151---[1] 85
130 Probenecid [1] Probenecid[1] D00475 --[1] 25
131 Probucol [1] Probucol[1] D00476 --[1] 66
132 Procarbazine [1] Procarbazine[1] D08423 --[1] 65
133 Progesterone [1] Progesterone[1] D00066 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[2] 76, 299
134 Proglumide [1] Proglumide[1] D01818 [1] CCKBR 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[1] 298
135 Proline [1] Proline[1] D00035 --[2] 94, 97
136 Promethazine [1] Promethazine[1] D00494 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 96
137 Propanoic acid [1] Propanoic acid---[2] 6, 271
138 Propantheline [2] Propantheline; Propantheline Bromide---[1] 26
139 Propiverine [1] Propiverine[1] D08441 [9] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[43] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
140 Propofol [2] Propofol; Propofol Injection[1] D00549 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[9] 6, 21, 22, 34, 46, 70, 75, 98, 296
141 Propranolol [2] Propanolol; Propranolol[1] D08443 [3] ADRB1,
ADRB2,
ADRB3 💬		[12] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 158, 167, 227, 278, 296
142 Propylene glycol [1] Propylene glycol[1] D00078 --[1] 51
143 Prothrombin [1] Prothrombin---[1] 288
144 Protirelin [1] Thyrotropin releasing hormone[1] D00176 [1] TRHR 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 80
145 Prucalopride [2] PRUCALOPRIDE; Resolor[1] D09205 [1] HTR4 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬[3] 13, 51, 96
146 Pseudoephedrine [1] Pseudoephedrine[1] D08449 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17
147 Psilocybin [2] Psilocybin; Psilocybine---[1] 6
148 PTC299 [1] PTC299---[1] 34
149 PTI-428 [1] PTI-428---[1] 299
150 PTI-801 [1] PTI-801---[1] 299
151 Puerarin [1] Puerarin---[1] 46
152 Pyrazole [2] 1H-Pyrazol; Pyrazole---[6] 2, 28, 46, 58, 75, 154
153 Pyridostigmine [3] Mestinon; PYRIDOSTIGMINE; PYRIDOSTIGMINE BROMIDE---[4] 3, 6, 11, 256
154 Pyridoxal phosphate [0] ---[1] 13
155 Pyridoxine [2] PYRIDOXINE; Vitamin B6[1] D08454 --[5] 6, 93, 145, 206, 320
156 Pyrimethamine [2] Daraprim; PYRIMETHAMINE[1] D00488 --[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265
157 Pyrrolidine [1] Pyrrolidine---[2] 28, 97