Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Valaciclovir [1] Valacyclovir[2] D08664 ,
D10518 		--[1] 65
2 Valbenazine [1] Valbenazine[1] D10675 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
3 Valdecoxib [1] Valdecoxib[1] D02709 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
4 Valerian [1] Valerian---[1] 6
5 Valganciclovir [1] Valganciclovir[1] D02495 --[4] 85, 97, 299, 331
6 Valiloxybate [1] Valiloxybate[1] D12240 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 6
7 Valproic acid [3] Valproate; VALPROATE SODIUM; Valproic acid[1] D00399 [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
8 Valsartan [3] Diovan; Entresto; Valsartan[1] D00400 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224
9 Vamorolone [1] VAMOROLONE[1] D11000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 97, 113
10 Vancomycin [1] Vancomycin[1] D00212 --[8] 13, 46, 70, 94, 96, 97, 296, 299
11 Vanillic acid [0] ---[2] 90, 302
12 Vardenafil [3] Levitra; Vardenafil; Vardenafilo[1] D08668 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[3] 13, 86, 299
13 Varenicline [2] Champix; VARENICLINE[1] D08669 [2] CHRNA4,
CHRNB2 💬		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53
14 Varicella zoster vaccine (live/attenuated) [1] Zostavax---[2] 46, 49
15 Varicella zoster vaccine (recombinant) [1] SHINGRIX---[3] 46, 96, 97
16 Vasopressin [1] Vasopressin[1] D00101 [3] AVPR1A,
AVPR1B,
AVPR2 💬		[5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 210
17 Vatelizumab [1] Vatelizumab---[2] 13, 97
18 Vatiquinone [1] VATIQUINONE[1] D10407 --[2] 18, 21
19 VB-201 [1] VB-201---[1] 97
20 Vedolizumab [2] Entyvio; VEDOLIZUMAB[1] D08083 [2] ITGA4,
ITGB7 💬		[15] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[3] 94, 96, 97
21 Velaglucerase alfa [3] GA-GCB; VELAGLUCERASE ALFA; VPRIV[1] D09029 [1] GBA1 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
22 Veledimex [1] Veledimex[1] D10678 --[1] 51
23 Velmanase alfa [3] LAMAZYM; RhLAMAN; VELMANASE ALFA[1] D11024 [1] MAN2B1 💬[2] Lysosome, Other glycan degradation 💬[1] 19
24 Veltuzumab [1] Veltuzumab[1] D09031 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
25 Velusetrag [1] Velusetrag[1] D09693 [1] HTR4 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬[1] 99
26 Venetoclax [1] Venetoclax[1] D10679 [1] BCL2 💬[43] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬[1] 28
27 Venglustat [2] GENZ-682452; Venglustat[1] D11633 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67
28 Venlafaxine [2] Venlafaxine; VENLAFAXINE HYDROCHLORIDE[1] D08670 [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46
29 Verapamil [3] Verapamil; VERAPAMIL HYDROCHLORIDE; Verapamil SR[1] D02356 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 58, 96, 140, 167
30 Verdiperstat [1] Verdiperstat[1] D11684 [1] MPO 💬[5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬[3] 2, 17, 127
31 Vestronidase alfa [3] Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa[1] D11004 [1] GUSB 💬[8] Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬[1] 19
32 Vibrio cholerae Inaba 48 classical biotype, heat inactivated [1] Dukoral---[1] 97
33 Vibrio cholerae Inaba 6973 El Tor biotype, formalin inactivated [1] Dukoral---[1] 97
34 Vibrio cholerae Ogawa 50 classical biotype, formalin inactivated [1] Dukoral---[1] 97
35 Vibrio cholerae Ogawa 50 classical biotype, heat inactivated [1] Dukoral---[1] 97
36 Vidofludimus [1] Vidofludimus---[5] 13, 46, 94, 96, 97
37 Vigabatrin [2] SABRIL; VIGABATRIN[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[2] 145, 158
38 Vilobelimab [2] IFX-1; Vilobelimab[1] D11838 [1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 43, 44, 269
39 Viltolarsen [1] VILTOLARSEN[1] D11528 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
40 Vinblastine [2] Vinblastine; Vinblastine sulfate[1] D08675 [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[2] 34, 65
41 Vincristine [2] Vincristine; Vincristine Sulfate[1] D08679 [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[4] 26, 34, 65, 331
42 Visilizumab [1] Visilizumab[1] D06314 [3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[2] 96, 97
43 Vismodegib [2] Erivedge; VISMODEGIB[1] D09992 [1] SMO 💬[5] Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬[1] 85
44 Vitamin A [1] Vitamin A[1] D06543 [2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90
45 Vitamin D [3] Calciferol; Cod liver oil; Vitamin D---[20] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299
46 Vitamin E [2] Alpha-tocopherol; Vitamin E[1] D02331 --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
47 Vobarilizumab [1] Vobarilizumab[1] D11005 --[1] 49
48 Voclosporin [1] Voclosporin[1] D09033 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 49, 222
49 Volanesorsen [1] Volanesorsen[1] D11648 [1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265
50 Volixibat [1] Volixibat[1] D11007 --[2] 93, 94
51 Von Willebrand factor human [7] Alphanate; Factor von Willebrand; HUMAN VON WILLEBRAND FACTOR; Humate-P; Von willebrand factor; Voncento; WILATE---[2] 64, 288
52 Vonicog alfa [3] Veyvondi; VON WILLEBRAND FACTOR; VONICOG ALFA[1] D08681 --[1] 288
53 Vonoprazan [1] Vonoprazan[1] D11784 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 63, 98
54 Voriconazole [2] Vfend; Voriconazole[1] D00578 --[2] 60, 299
55 Vorinostat [1] Vorinostat[1] D06320 [11] HDAC1,
HDAC10,
HDAC11,
HDAC2,
HDAC3,
HDAC4,
HDAC5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬		[17] Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬[2] 75, 96
56 Vortioxetine [1] Vortioxetine[1] D10184 [7] HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬		[5] Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[1] 6
57 Vosoritide [1] Vosoritide[1] D11190 [1] NPR2 💬[5] Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 276
58 VX-659 [1] VX-659---[1] 299
59 VX-702 [1] VX-702---[1] 46