Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Oat [1] Oats---[1] 97
2 Obatoclax [1] Obatoclax---[1] 60
3 Obeticholic acid [4] 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva[1] D09360 [1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296
4 Obexelimab [1] Obexelimab[1] D11496 [1] CD19 💬[5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[1] 300
5 Obinutuzumab [2] GAZYVARO; Obinutuzumab[1] D09321 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[4] 43, 44, 49, 222
6 Ocrelizumab [3] Ocrelizumab; OCREVUS; RhuMAb 2H7[1] D05218 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 46, 49
7 Octreotide [3] OCTREOTIDE; OCTREOTIDE ACETATE; Sandostatin LAR[1] D00442 [1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[7] 67, 75, 84, 85, 89, 193, 227
8 Odevixibat [1] Odevixibat[1] D11716 [1] SLC10A2 💬[1] Bile secretion 💬[3] 296, 297, 338
9 Odiparcil [1] Odiparcil---[1] 19
10 Ofatumumab [4] Arzerra; HuMax-CD20; Kesimpta; Ofatumumab[1] D09314 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 35, 46
11 Olanzapine [2] Olanzapine; Zyprexa[1] D00454 [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
12 Olaparib [1] Olaparib[1] D09730 [2] PARP1,
PARP2 💬		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285
13 Olea europaea leaf [1] Olive---[5] 13, 35, 49, 53, 162
14 Oleic Acid [1] Oleic Acid[1] D02315 --[2] 13, 299
15 Olenasufligene relduparvovec [1] OLENASUFLIGENE RELDUPARVOVEC---[1] 19
16 Olesoxime [1] Olesoxime[1] D11213 --[3] 2, 3, 13
17 Olipudase alfa [1] OLIPUDASE ALFA[1] D10820 [1] SMPD1 💬[5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19
18 Olive oil [1] Olive oil[1] D03311 --[5] 13, 35, 49, 53, 162
19 Olokizumab [1] Olokizumab[1] D12487 [1] IL6 💬[51] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 46, 96
20 Olsalazine [1] Olsalazine[1] D08295 --[1] 271
21 OM85 [1] Broncho-Vaxom---[1] 85
22 Omadacycline [1] Omadacycline[1] D09647 --[1] 299
23 Omalizumab [2] Omalizumab; Xolair[1] D05251 [1] FCER1A 💬[4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299
24 Omaveloxolone [1] Omaveloxolone[1] D10964 [1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18
25 Omega-3 fatty acids [5] Omega-3; Omega-3 fatty acid; Omega-3 fatty acids; OMEGA-3-ACID TRIGLYCERIDES; Phospholipids---[8] 13, 46, 49, 53, 66, 79, 96, 299
26 Omega-3-carboxylic acids [1] Epanova---[1] 96
27 Omeprazole [4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[1] D00455 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
28 Omidubicel [1] Omidubicel---[1] 60
29 Omigapil [1] Omigapil---[1] 113
30 Onasemnogene abeparvovec [3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma[1] D11559 [1] SMN1 💬-[1] 3
31 Ondansetron [1] Ondansetron[1] D00456 [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107
32 Ontamalimab [1] Ontamalimab---[2] 96, 97
33 Opicapone [2] Ongentys; OPICAPONE[1] D10825 [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6
34 Opicinumab [1] Opicinumab[1] D11767 [1] LINGO1 💬-[1] 13
35 Oprelvekin [5] IL-11; Interleukin 11; Interleukin-11; Oprelvekin; Recombinant interleukin-11[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[2] 96, 288
36 ORE-1001 [0] ---[1] 97
37 Orelabrutinib [1] Orelabrutinib[1] D12160 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63
38 Orilanolimab [1] ORILANOLIMAB[1] D12144 [1] FCGRT 💬-[1] 61
39 ORM-12741 [1] ORM-12741---[1] 51
40 Ornithine [1] Ornithine[1] D08302 --[2] 245, 251
41 Orvepitant [1] ORVEPITANT[1] D09650 [1] TACR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 85
42 Oseltamivir [1] Oseltamivir[1] D08306 --[2] 97, 299
43 Osilodrostat [1] OSILODROSTAT[1] D11061 [1] CYP11B2 💬[3] Aldosterone synthesis and secretion, Metabolic pathways, Steroid hormone biosynthesis 💬[1] 75
44 Otelixizumab [1] Otelixizumab[1] D08959 [3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46
45 Otilimab [1] OTILIMAB[1] D11343 [1] CSF2 💬[16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46
46 Oxaloacetic acid [1] Oxaloacetate---[2] 6, 11
47 Oxandrolone [1] Oxandrolone[1] D00462 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 211, 285
48 Oxatomide [1] Oxatomide[1] D01773 [1] ALOX5 💬[6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113
49 Oxcarbazepine [2] Oxcarbazepine; Trileptal[1] D00533 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13
50 Oxiconazole [1] Oxiconazole[1] D08313 --[1] 160
51 Oxybuprocaine [1] Oxybuprocaine[1] D08319 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6
52 Oxybutynin [1] Oxybutynin[1] D00465 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53
53 Oxycodone [2] Oxycodone; OXYCODONE HYDROCHLORIDE[1] D05312 [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298
54 Oxygen [3] Medical air; Nitrogen; Oxygen[1] D00003 --[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
55 Oxymatrine [1] Oxymatrine---[1] 37
56 Oxymorphone [1] Opana[1] D08323 [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70
57 Oxyquinoline [1] Oxine[1] D05321 --[1] 13
58 Oxytocin [2] Oxytocin; Syntocinon[1] D00089 [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226
59 Oyster [1] Oyster---[1] 84
60 Ozanezumab [1] Ozanezumab[1] D10331 [1] RTN4 💬[1] Alzheimer disease 💬[1] 2
61 Ozanimod [2] Ozanimod; Zeposia[1] D10968 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97
62 Ozone [1] Ozone---[3] 49, 51, 226
63 Ozoralizumab [1] Ozoralizumab[1] D09944 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46