Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Ebselen [1] Ebselen---[1] 299
2 Eculizumab [2] ECULIZUMAB; SOLIRIS[1] D03940 [1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222
3 Edaravone [3] Edaravone; Methylphenylpyrazolone; Norphenazone[1] D01552 --[3] 2, 6, 22
4 Edasalonexent [1] EDASALONEXENT[1] D12181 [1] RELA 💬[76] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[1] 113
5 Edetic acid [1] EDTA[1] D00052 --[1] 60
6 Edonerpic [1] Edonerpic---[1] 149
7 Edoxaban [1] Edoxaban[1] D09710 [1] F10 💬[1] Complement and coagulation cascades 💬[2] 46, 88
8 Edratide [1] Edratide[1] D03957 --[1] 49
9 Efalizumab [2] EFALIZUMAB; Raptiva[1] D03959 [1] ITGAL 💬[12] Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
10 Efanesoctocog alfa [1] Efanesoctocog alfa[1] D12441 --[1] 288
11 Efavaleukin alfa [1] EFAVALEUKIN ALFA[1] D11612 --[2] 49, 97
12 Efavirenz [2] Efavirenz; SUSTIVA[1] D00896 --[1] 265
13 Efgartigimod alfa [1] EFGARTIGIMOD ALFA[1] D11876 [1] FCGRT 💬-[6] 11, 14, 35, 53, 63, 162
14 Efineptakin alfa [1] NT-I7[1] D11957 --[1] 25
15 Eflornithine [1] Eflornithine[1] D07883 [1] ODC1 💬[3] Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways 💬[1] 65
16 Efmarodocokin alfa [2] Efmarodocokin alfa; IL-22Fc[1] D11953 [1] IL22 💬[4] Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Th17 cell differentiation 💬[2] 96, 97
17 Egg [1] Egg---[2] 96, 310
18 Egg white [2] Albumen; Egg white---[1] 96
19 Egg yolk [1] Egg yolk---[1] 310
20 Elafibranor [1] ELAFIBRANOR[1] D11208 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94
21 Elafin [1] Elafin---[1] 86
22 Elamipretide [1] Elamipretide[1] D10925 --[2] 21, 324
23 Eldecalcitol [1] Eldecalcitol[1] D07578 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 46
24 Eleclazine [1] Eleclazine[1] D11155 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 58
25 Elexacaftor [3] ELEXACAFTOR; Kaftrio; Trikafta[1] D11507 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
26 Elezanumab [1] Elezanumab[1] D11355 [1] RGMA 💬[2] Axon guidance, TGF-beta signaling pathway 💬[1] 13
27 Eliglustat [2] Cerdelga; Eliglustat[1] D09893 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
28 Eliprodil [1] Eliprodil---[1] 6
29 Elivaldogene autotemcel [1] Elivaldogene autotemcel[1] D12150 [1] ABCD1 💬[2] ABC transporters, Peroxisome 💬[1] 20
30 Elobixibat [1] Elobixibat[1] D10796 [1] SLC10A2 💬[1] Bile secretion 💬[1] 6
31 Elosulfase alfa [3] Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS[1] D10333 [1] GALNS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
32 Elotuzumab [1] Elotuzumab[1] D09337 [1] SLAMF7 💬-[1] 28
33 Eltoprazine [1] ELTOPRAZINE---[1] 6
34 Eltrombopag [3] ELTROMBOPAG; Promacta; REVOLADE---[5] 60, 63, 65, 284, 285
35 ELX-02 [1] ELX-02---[3] 19, 218, 299
36 Emapalumab [1] EMAPALUMAB[1] D11120 [1] IFNG 💬[32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[3] 49, 65, 107
37 Emeramide [1] Emeramide---[2] 5, 17
38 Emicizumab [2] Emicizumab; Hemlibra[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
39 Emixustat [1] Emixustat[1] D10348 --[1] 301
40 Emodin [1] Emodin---[1] 67
41 Empagliflozin [2] Empagliflozin; Jardiance[1] D10459 [1] SLC5A2 💬-[6] 58, 65, 67, 72, 97, 257
42 Emtricitabine [2] Emtricitabine; TRUVADA[1] D01199 --[4] 25, 93, 265, 325
43 Enalapril [2] Enalapril; Enalapril Maleate[1] D07892 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
44 Endostatin [1] Endostatin---[1] 34
45 Enfuvirtide [1] Enfuvirtide[1] D02499 --[2] 25, 265
46 Enoxaparin [1] Enoxaparin[1] D07510 [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[1] 46
47 Entacapone [5] COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo[1] D00781 [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17
48 Entecavir [1] Entecavir[2] D04008 ,
D07896 		--[6] 46, 56, 96, 97, 107, 271
49 Enzastaurin [1] Enzastaurin[1] D11935 [1] PRKCB 💬[71] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Amoebiasis, Amphetamine addiction, B cell receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Circadian entrainment, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, EGFR tyrosine kinase inhibitor resistance, Endocrine and other factor-regulated calcium reabsorption, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, GABAergic synapse, Gap junction, Gastric acid secretion, Glioma, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Insulin secretion, Leishmaniasis, Leukocyte transendothelial migration, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, Pancreatic secretion, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phosphatidylinositol signaling system, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Sphingolipid signaling pathway, Spinocerebellar ataxia, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, mTOR signaling pathway 💬[1] 168
50 Eperisone [1] EPERISONE[1] D07898 --[1] 2
51 Ephedrine [3] Efedrina; Ephedrine; EPHEDRINE HYDROCHLORIDE[1] D00124 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11
52 EPI-589 [1] EPI-589---[2] 2, 6
53 Epicatechin [1] Epicatechin---[2] 86, 113
54 Epigallocatechin [1] Epigallocatechin---[5] 8, 13, 28, 85, 113
55 Epigallocatechin gallate [3] EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299
56 Epinephrine [3] Epinephrine; Lidocaine; Xylocaine[1] D00095 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 46, 70, 96
57 Eplerenone [1] Eplerenone[1] D01115 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[4] 75, 113, 210, 215
58 Epoprostenol [6] EPOPROSTENOL; Epoprostenol for injection; EPOPROSTENOL SODIUM; Flolan; Prostacyclin; Veletri[1] D00106 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
59 Epratuzumab [1] EPRATUZUMAB[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
60 Ergocalciferol [3] Ergocalciferol; Vitamin D; Vitamin D2[1] D00187 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299
61 Ergoloid mesylate [2] Dihydroergotoxine Mesylate; Ergoloid Mesylate---[2] 6, 206
62 Erlotinib [1] Erlotinib[1] D07907 [1] EGFR 💬[48] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬[1] 94
63 Erythrityl tetranitrate [0] [1] D04051 [2] NPR1,
NPR2 💬		[10] Aldosterone synthesis and secretion, Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
64 Erythromycin [1] Erythromycin[1] D00140 --[5] 6, 36, 164, 228, 291
65 Erythropoietin [4] Epoetin alfa; Epoetin beta; Erythropoietin; NeoRecormon---[10] 2, 6, 13, 18, 22, 46, 47, 70, 95, 96
66 Escherichia coli [1] Escherichia coli---[2] 53, 78
67 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[1] D07913 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46
68 Esketamine [3] ESKETAMINE; KETAMINE; S-ketamine[1] D07283 [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 4, 70
69 Esmolol [1] Esmolol[1] D07916 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 58
70 Esomeprazole [3] Esomeprazole; Nexium; Omeprazole[1] D07917 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
71 Estetrol [1] Estetrol[2] D11513 ,
D11514 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 53
72 Estradiol [1] Estradiol[1] D00105 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
73 Estradiol valerate [1] Estradiol valerate[1] D01413 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 65
74 Estriol [1] Estriol[2] D00185 ,
D01986 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 227
75 Eszopiclone [2] Eszopiclone; Zopiclone[1] D02624 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46
76 Etamsylate [1] ETAMSYLATE[1] D01282 --[1] 227
77 Etanercept [4] Benepali; ENBREL; Erelzi; Etanercept[1] D00742 [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
78 Eteplirsen [2] ETEPLIRSEN; Exondys 51[1] D09900 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
79 Ethambutol [1] Ethambutol[1] D07925 --[2] 84, 299
80 Ethanol [3] Alcohol; Ethanol; PREDNISONE[1] D06542 --[5] 58, 97, 279, 280, 298
81 Ethanolamine [1] Ethanolamine---[1] 279
82 Ethanolamine oleate [1] Ethanolamine oleate[1] D02276 --[1] 279
83 Ethinylestradiol [3] Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 777[1] D00554 [1] ESR1 💬[9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 13, 46, 49, 299
84 Ethiodized oil [1] Lipiodol[2] D04082 ,
D04083 		--[1] 280
85 Etidronic acid [1] Etidronate[1] D02373 --[1] 27
86 Etiprednol dicloacetate [1] Etiprednol dicloacetate[1] D04100 --[1] 96
87 Etodolac [1] Etodolac[1] D00315 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
88 Etomidate [1] Etomidate[1] D00548 [1] GABRA1 💬[6] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[1] 6
89 Etoposide [1] Etoposide[1] D00125 [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
90 Etoricoxib [1] ETORICOXIB[1] D03710 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 46, 271
91 Etrasimod [1] Etrasimod[1] D10930 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98
92 Etravirine [3] ETRAVIRINA; Etravirine; INTELENCE[1] D04112 --[1] 18
93 Etrolizumab [1] ETROLIZUMAB[1] D09901 [1] ITGB7 💬[11] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer 💬[2] 96, 97
94 Eupatilin [1] Eupatilin---[2] 46, 271
95 Everolimus [4] Afinitor; Certican; EVEROLIMUS; Votubia[1] D02714 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[9] 34, 67, 89, 96, 137, 157, 158, 228, 277
96 Evinacumab [1] EVINACUMAB[1] D11753 [1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79
97 Evobrutinib [1] Evobrutinib[1] D12467 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 13, 46, 49
98 Evolocumab [2] Evolocumab; Repatha[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222
99 Exametazime [1] Exametazime[1] D01109 --[1] 6
100 Exenatide [3] BYDUREON; Byetta; Exenatide[1] D04121 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233
101 Ezetimibe [2] Ezetimibe; Ezetrol[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
102 Ezogabine [4] Ezogabine; Potiga; RETIGABINE; Trobalt[1] D09569 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬		[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144
103 Ezutromid [1] Ezutromid---[1] 113