KEGG DRUG

Search results

No.	DrugBank	Drug (Description in trials)	KEGG DRUG	KEGG GENES	KEGG PATHWAY	Disease ID
1	Acetaminophen	[4] Acetaminophen; Paracetamol; Tylenol; Ultracet	[1] D00217 (Name: Acetaminophen)	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬	[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2	Acetylsalicylic acid (Synonym: Acetaminophen 250mg Aspirin 250mg Caffeine 65mg)	[2] Acetylsalicylic Acid; Aspirin	[1] D00109	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬	[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
3	Caffeine (Synonym: Adults Acetaminophen and Caffeine Pain Reliever Fever Reducer)	[1] Caffeine	[2] D00528 , D01453	[11] ADORA1, ADORA2A, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬	[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	[8] 2, 6, 21, 46, 78, 96, 97, 265
4	Dextromethorphan (Synonym: Acetaminophen/dextromethorphan/pseudoephedrine)	[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta	[1] D03742	[6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬	[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬	[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
5	Diphenhydramine (Synonym: Up and Up Acetaminophen PM Extra Strength)	[2] Diphenhydramine; Diphenhydramine hydrochloride	[1] D00300	[1] HRH1 💬	[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬	[8] 11, 13, 49, 51, 70, 86, 222, 256
6	Ibuprofen (Synonym: Advil Dual Action With Acetaminophen)	[2] Ibuprofen; IBUPROFEN 200MG	[1] D00126	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬	[7] 13, 46, 65, 107, 113, 271, 299
7	Oxycodone (Synonym: Oxycodone/acetaminophen)	[2] Oxycodone; OXYCODONE HYDROCHLORIDE	[1] D05312	[3] OPRD1, OPRK1, OPRM1 💬	[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬	[5] 6, 13, 70, 226, 298
8	Phenylephrine (Synonym: Cough Syrup DM Decongestant and Expectorant With Acetaminophen)	[1] Phenylephrine	[1] D08365	[3] ADRA1A, ADRA1B, ADRA1D 💬	[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬	[1] 22
9	Pseudoephedrine (Synonym: Acetaminophen/pseudoephedrine/dextromethorphan/doxylamine)	[1] Pseudoephedrine	[1] D08449	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	[1] 17
10	Tramadol (Synonym: Tramadol Hydrochloride and Acetaminophen)	[2] Tramadol; Ultracet	[1] D08623	[1] OPRM1 💬	[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬	[5] 46, 70, 78, 226, 271