Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	MASP2	[3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19	D11531	Narsoplimab	[4] 64, 66, 109, 222
2	CFB	[3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19	D12251	Iptacopan	[5] 61, 62, 66, 109, 222
3	C5	[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus	D03940	Eculizumab	[7] 11, 13, 14, 61, 62, 109, 222
4	C5	[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus	D11054	Ravulizumab	[7] 2, 11, 13, 50, 62, 66, 109
5	C5	[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus	D11473	Nomacopan	[3] 62, 109, 162
6	C5	[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus	D11696	Crovalimab	[2] 62, 109