Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Pertussis 💬
 [2] C1R, C1S 💬 D10845 💬 Conestat alfa [1] 61 💬
2 Pertussis 💬
 [1] C1S 💬 D11530 💬 Sutimlimab [1] 61 💬
3 Pertussis 💬
 [1] C3 💬 D11613 💬 Pegcetacoplan [4]  2 , 61, 62, 222 💬
4 Pertussis 💬
 [1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
5 Pertussis 💬
 [1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
6 Pertussis 💬
 [1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
7 Pertussis 💬
 [1] C5 💬 D11477 💬 Pozelimab [2] 11, 62 💬
8 Pertussis 💬
 [1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
9 Pertussis 💬
 [1] C5 💬 D11838 💬 Vilobelimab [3] 43, 44, 269 💬
10 Pertussis 💬
 [1] C5 💬 D12357 💬 Zilucoplan [3]  2 , 11, 62 💬
11 Pertussis 💬
 [5] IL10, IL1A, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
12 Pertussis 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
13 Pertussis 💬
 [1] IL1A 💬 D11253 💬 Bermekimab [1] 51 💬
14 Pertussis 💬
 [2] IL1A, IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
15 Pertussis 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
16 Pertussis 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
17 Pertussis 💬
 [1] IL23A 💬 D10912 💬 Brazikumab [2] 96, 97 💬
18 Pertussis 💬
 [1] IL23A 💬 D10438 💬 Guselkumab [5] 37, 41, 51, 96, 97 💬
19 Pertussis 💬
 [1] IL23A 💬 D11123 💬 Mirikizumab [3] 37, 96, 97 💬
20 Pertussis 💬
 [1] IL23A 💬 D11052 💬 Risankizumab [4] 37, 96, 97, 271 💬
21 Pertussis 💬
 [1] IL23A 💬 D10400 💬 Tildrakizumab [2] 162, 271 💬
22 Pertussis 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
23 Pertussis 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
24 Pertussis 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
25 Pertussis 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
26 Pertussis 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
27 Pertussis 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
28 Pertussis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
29 Pertussis 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
30 Pertussis 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
31 Pertussis 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
32 Pertussis 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
33 Pertussis 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
34 Pertussis 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
35 Pertussis 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
36 Pertussis 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
37 Pertussis 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
38 Pertussis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬